Researchers from UCLA’s Jonsson Comprehensive Cancer Center have identified a cell-permeable peptide that inhibits a hepatitis C virus protein and blocks the viral replication that can lead to liver cancer and cirrhosis.
The finding by Dr. Samuel French, a UCLA assistant professor of pathology and senior author of the research, builds on previous work by French’s laboratory that identified two cellular proteins that are important factors in hepatitis C virus infection. (more…)
*Studies of diving beetles suggest sperm evolution may be driven by changes in female reproductive organs, challenging the paradigm of post-mating sexual selection being driven mostly by competition among sperm.*
Studying female reproductive tracts and sperm in diving beetles (Dytiscidae), researchers from the University of Arizona and Syracuse University have obtained a glimpse into a bizarre and amazing world of sperm that can take on a variety of forms – including joining together into conglomerates that navigate the twisted mazes of the female reproductive tract.
Analyses of the evolutionary relationships among diving beetles reveal that sperm form appears to follow function dictated by female reproductive organs. (more…)
A relatively fast, easy and inexpensive technique for inducing nanorods – rod-shaped semiconductor nanocrystals – to self-assemble into one-, two- and even three-dimensional macroscopic structures has been developed by a team of researchers with the U.S. Department of Energy (DOE)’s Lawrence Berkeley National Laboratory (Berkeley Lab). This technique should enable more effective use of nanorods in solar cells, magnetic storage devices and sensors. It should also help boost the electrical and mechanical properties of nanorod-polymer composites.
Leading this project was Ting Xu, a polymer scientist who holds joint appointments with Berkeley Lab’s Materials Sciences Division and the University of California (UC) Berkeley’s Departments of Materials Sciences and Engineering, and Chemistry. Xu and her research group used block copolymers – long sequences or “blocks” of one type of monomer bound to blocks of another type of monomer – as a platform to guide the self-assembly of nanorods into complex structures and hierarchical patterns. Block copolymers have an innate ability to self-assemble into well-defined arrays of nano-sized structures over macroscopic distances. (more…)
ANN ARBOR, Mich.— Using a liquid laser, University of Michigan researchers have developed a better way to detect the slight genetic mutations that might predispose a person to a particular type of cancer or other diseases.
Their results are published in the current edition of the German journal Angewandte Chemie. (more…)
Researchers at Yale University have developed a new way of exposing the atomic attachments that keep complex molecules in precise alignment. The new method could provide insight into the mechanics of a variety of molecular structures, potentially aiding efforts to manipulate them for drug discovery and other purposes.
“The method appears likely to become a central tool for the characterization of processes that depend on supramolecular associations,” said Mark Johnson, a Yale chemistry professor and the principal investigator of the technique, which is described in a paper published this month in the journal Science. Supramolecular associations are interactions taking place between molecules, rather than within them. (more…)
The communities of marine microorganisms that make up half the biomass in the oceans and are responsible for half the photosynthesis the world over, mostly remain enigmatic. A few abundant groups have had their genomes described, but the natures and functions of the rest remain mysterious.(more…)
For his discoveries about the lives and deaths of stars, the exotic physics of black holes and the origin of chemical elements, UA Regents’ Professor David Arnett has been honored with the Henry Norris Russell Lectureship.
What happens when a star dies? How does a black hole form? What makes the chemical elements that form the building blocks of stars, planets and living beings?(more…)
*Rizia Bardhan, a postdoc at the Molecular Foundry, selected to Forbes’ ’30 under 30′ list*
On a typical day, Rizia Bardhan walks through the doors of Lawrence Berkeley National Laboratory’s Molecular Foundry and immerses herself in the tricky business of tweaking optical spectroscopy equipment to study phase transitions in metal hydrides.
It’s fair to say that what she does is difficult to grasp. Why she does it is easy: “I want to help solve big problems. That’s why I’m here,” she says. (more…)
