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More Sophisticated Wiring, Not Just a Bigger Brain, Helped Humans Evolve Beyond Chimps

By Guest PostAugust 26, 2012Scienceamino acids, autism, bipolar syndrome, brain disease, brain region, brain tissue, cellular protein, chimp, chimp brain, chimpanzee, circadian rhythm, clock, daniel geschwind, DNA, expression, foxp1, foxp2, frontal cortex, frontal lobe, function, gene manufacture, genevieve konopka, genome, hippocampus, human, human brain, human evolution, human gene, hypothesis, jeremy davis turak, kellen winden, plasticity, schizophrenia, striatum, tara friedrich, ucla

Human and chimp brains look anatomically similar because both evolved from the same ancestor millions of years ago. But where does the chimp brain end and the human brain begin?

A new UCLA study pinpoints uniquely human patterns of gene activity in the brain that could shed light on how we evolved differently than our closest relative. The identification of these genes could improve understanding of human brain diseases like autism and schizophrenia, as well as learning disorders and addictions.

The research appears Aug. 22 in the advance online edition of the journal Neuron. (more…)

UCLA Researchers Identify Peptide That Inhibits Replication of Hepatitis C Virus

By Guest PostFebruary 8, 2012Scienceantiviral, block replication, cell permeable peptide, cellular factor, cellular protein, heat shock proteins, hepatitis, hepatitis c therapy, hepatitis c virus, hsps, interferon, mass spectrometry, natural compound, non structural protein 5a, ns5a, peptide, protein, quercetin, ribavirin, samuel french, synthesis, tissue culture, viral replication, viral translation level, virus infection

Researchers from UCLA’s Jonsson Comprehensive Cancer Center have identified a cell-permeable peptide that inhibits a hepatitis C virus protein and blocks the viral replication that can lead to liver cancer and cirrhosis.

The finding by Dr. Samuel French, a UCLA assistant professor of pathology and senior author of the research, builds on previous work by French’s laboratory that identified two cellular proteins that are important factors in hepatitis C virus infection. (more…)

Tag Archives: cellular protein

More Sophisticated Wiring, Not Just a Bigger Brain, Helped Humans Evolve Beyond Chimps

UCLA Researchers Identify Peptide That Inhibits Replication of Hepatitis C Virus