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Mutation Breaks HIV’s Resistance to Drugs, Says MU Researcher

By Guest PostSeptember 22, 2012Health172k, 172k mutation, aids, atsuko hachiya, cellular machinery, drug, hiv, hiv strain, hiv-infected, human, immunodeficiency, inhibitors, missouri, mutation, nnrtis, non nucleoside, nrtis, nucleoside, patient, polymorphism, resistant, reverse, stefan sarafianos, transcriptase, university, virus

Doctors can improve treatment programs using this knowledge

COLUMBIA, Mo. – The human immunodeficiency virus (HIV) can contain dozens of different mutations, called polymorphisms. In a recent study an international team of researchers, including University of Missouri scientists, found that one of those mutations, called 172K, made certain forms of the virus more susceptible to treatment. Soon, doctors will be able to use this knowledge to improve the drug regimen they prescribe to HIV-infected individuals.

“The 172K polymorphism makes certain forms of HIV less resistant to drugs,” said Stefan Sarafianos, corresponding author of the study and a researcher at MU’s Bond Life Sciences Center. “172K doesn’t affect the virus’ normal activities. In some varieties of HIV that have developed resistance to drugs, when the 172K mutation is present, resistance to two classes of anti-HIV drugs is suppressed. We estimate up to 3 percent of HIV strains carry the 172K polymorphism.” (more…)

World’s Most Powerful Digital Camera Begins Hunt for Dark Energy

By Guest PostSeptember 22, 2012Scienceancient starlight, atmospheric condition, billion years, brazil, brenna flaugher, camera, cerro tololo, Chicago, Chile, chilean andes, chris smith, dark energy, des, distant galaxy, earth, expansion, fermilab, galaxy cluster, Germany, gravitational lensing, inter american, james siegrist, kavli institute, mystery, ngc 1365, noao, observatory, physics, southern sky, spain, spiral galaxy, switzerland, telescope, united kingdom, universe, university, victor m blanco

Eight billion years ago, rays of light from distant galaxies began their long journey to Earth. That ancient starlight has now found its way to a mountaintop in Chile, where the newly constructed Dark Energy Camera, the most powerful sky-mapping machine ever created, has captured and recorded it for the first time.

That light may hold within it the answer to one of the biggest mysteries in physics: Why the expansion of the universe is speeding up. (more…)

New Study Analyzes Why People Are Resistant to Correcting Misinformation, Offers Solutions

By Guest PostSeptember 21, 2012Scienceautism, childhood, colleen seifert, decision, erroneous belief, fiction, global warming, health care, ideology, information, michigan, misinformation, norbert schwarz, President Obama, queensland, reform, rumor, stephan lewandowsky, ullrich ecker, united states, university, vaccine, western australia

ANN ARBOR, Mich.— Childhood vaccines do not cause autism. President Obama was born in the United States. Global warming is confirmed by science. And yet, many people believe claims to the contrary.

In a study appearing in the current issue of Psychological Science in the Public Interest, researchers from the University of Michigan, University of Western Australia and University of Queensland examined factors that cause people to resist correcting misinformation.

Misinformation can originate from rumors but also fiction, government and politicians, and organizations, the researchers say. (more…)

Shrinking Snow Depth on Arctic Sea Ice Threatens Ringed Seal Habitat

By Guest PostSeptember 20, 2012EnvironmentArctic, atmospheric sciences, brendan kelly, cecilia bitz, climate change, climate model, ice, important factor, paul hezel, predict, pups, sea ice, seals, shrink, snowfall pattern, thermodynamic impact, thickness, university, Washington

As sea ice in the Arctic continues to shrink during this century, more than two thirds of the area with sufficient snow cover for ringed seals to reproduce also will disappear, challenging their survival, scientists report in a new study.

The ringed seal, currently under consideration for threatened species listing, builds caves to rear its young in snow drifts on sea ice. Snow depths must be on average at least 20 centimeters, or 8 inches, to enable drifts deep enough to support the caves. (more…)

Blind Cavefish Use Teeth to Find Their Way, New UMD Research Shows

By Guest PostSeptember 19, 2012Natureastroblepus pholeter, brain, catfish, cavefish, daphne soares, dark, darkness, denticles, dentin, ecuador, ecuadorian cave, enamel, evolutionary phenomenon, human ear, maryland, mathematical, mechanosensory part, natural sciences, navigate, neuromasts, sensory use, single cave, skin teeth, teeth, university, unknown, water, way

COLLEGE PARK, Md. — In a single cave in Ecuador, a species of cavefish has evolved to do something perhaps unique to them, navigate with their teeth.

The sensory use of these teeth, which are not in their mouths, but protrude from their skin, appears to be a previously unknown evolutionary phenomenon, one that may not exist anywhere outside this one cave, say researchers at the University of Maryland, National Institutes of Health and Pontificia Universidad Católica del Ecuador who brought to light this fascinating new adaptation to life in dark, swiftly flowing waters. (more…)

CU Mathematicians Show How Shallow Waves May Help Explain Tsunami Power

By Guest PostSeptember 19, 2012Scienceboulder, colorado, douglas baldwin, earthquake, interaction height, Japan, los angeles, low tide, mark ablowitz, mathematical equation, Mexico, nonlinear, nonlinearity, nuevo vallarta, ocean wave, pacific ocean, physics, tsunami, university, venice beach, wave height, wave watching

While wave watching is a favorite pastime of beachgoers, few notice what is happening in the shallowest water. A closer look by two University of Colorado Boulder applied mathematicians has led to the discovery of interacting X- and Y-shaped ocean waves that may help explain why some tsunamis are able to wreak so much havoc.

Professor Mark Ablowitz and doctoral student Douglas Baldwin repeatedly observed such wave interactions in ankle-deep water at both Nuevo Vallarta, Mexico, and Venice Beach, Calif., in the Pacific Ocean — interactions that were thought to be very rare but which actually happen every day near low tide. There they saw single, straight waves interacting with each other to form X- and Y-shaped waves as well as more complex wave structures, all predicted by mathematical equations, said Ablowitz. (more…)

Too Much Information? It Depends …

By Guest PostSeptember 18, 2012Economyadvertising, brown university, cognitive reflection test, colorado, crt, explanation fiends, explanation foes, hypothesis, illusion, julia shube, philip fernbach, psychologist, robert st louis, steven sloman, university

In a new study, psychologists at Brown University and the University of Colorado found that while some people require a detailed explanation of how a product works before they’ll be willing to pay more, others became less willing to pay when confronted with that additional detail. A simple, standard test predicted the desire for detail — who wants more, who wants less.

PROVIDENCE, R.I. [Brown University] — A study published online in the Journal of Consumer Research finds that people can differ widely on the level of detail makes them feel they understand something. In experiments, the very same explanations that some subjects required before they would pay top dollar seemed to drive down what others were willing to pay. The natural trick for a marketer would be to figure out which customers are which. The study does that, too.

“The fact is that people differ,” said Steven Sloman, professor of cognitive, linguistic, and psychological sciences at Brown University and an author on the paper. “Your advertising, your marketing, and your understanding of people has to be guided by an appreciation of who you are talking to.” (more…)

Out of This World

By Guest PostSeptember 18, 2012Sciencebuilding block, colloids, computer chip, crystalline structure, delaware, eric m furst, functional material, gravity, international space station, iss, james swan, lattice, magnetic field, microscopic particle, Nanotechnology, NASA, novel nanomaterial, paramagnetic colloid, paula vasquez, phase separation, pnas, reality, scalable, self assemble, university

UD professor reports smart fluids research in scientific journal

Imagine a computer chip that can assemble itself.

According to Eric M. Furst, professor of chemical and biomolecular engineering at the University of Delaware, engineers and scientists are closer to making this and other scalable forms of nanotechnology a reality as a result of new milestones in using nanoparticles as building blocks in functional materials.

Furst and his postdoctoral researchers, James Swan and Paula Vasquez, along with colleagues at NASA, the European Space Agency, Zin Technologies and Lehigh University, reported the finding Sept. 17 in an article in the Proceedings of the National Academies of Science (PNAS) online edition. (more…)

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