Tag Archives: ucla

UCLA Relies on Breakthrough ‘Big Data’ Technology from IBM To Help Patients with Traumatic Brain Injuries

Bedside Early-Warning System from IBM and Excel Medical Electronics Can Analyze Large Amounts of Data in Real Time to Predict Dangerous Changes in a Patient’s Condition

Armonk, N.Y. and Los Angeles, CA – 26 Mar 2013: IBM, and Excel Medical Electronics (EME) are collaborating with the UCLA Department of Neurosurgery in a study to test the effectiveness of a real-time alarm intended to predict rising brain pressure in patients with traumatic brain injuries. The experimental system uses big data analytics software developed by IBM Research and EME that analyzes in real-time streams of vital signs continuously collected from the bedside monitor to spot subtle changes in the patient’s pulse, blood and intracranial pressure, heart activity, and respiration, signaling that dangerous high-risk increases in brain pressure are on the way. (more…)

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High-speed rail study finds that remote cities benefit from connection to global hubs

Bullet trains fuel real-estate booms, improve quality of life and create other unintended consequences by sharply reducing commute times from smaller cities to large megacities, economists from UCLA and China’s Tsinghua University observed in a new study in China. A similar dynamic, they said, could play out as California builds its own high-speed rail system.
    
Because high-speed rail effectively brings cities closer together by reducing travel times, it allows people to enjoy many of the benefits of big cities while living in “second-tier” cities far from the pollution and congestion. By making second-tier cities attractive to those who would otherwise flock to global hubs, bullet trains could act as a safety valve for crowded megacities in the developing world and ease the effects of overpopulation, the study authors report. (more…)

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Predicting hotspots for future flu outbreaks

This year’s unusually long and rocky flu season would be nothing compared to the pandemic that could occur if bird flu became highly contagious among humans, which is why UCLA researchers and their colleagues are creating new ways to predict where an outbreak could emerge.

“Using surveillance of influenza cases in humans and birds, we’ve come up with a technique to predict sites where these viruses could mix and generate a future pandemic,” said lead author Trevon Fuller, a UCLA postdoctoral research fellow at the Institute of the Environment and Sustainability’s Center for Tropical Research. (more…)

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UCLA Researchers Further Refine ‘Nanovelcro’ Device to Grab Single Cancer Cells from Blood

Improvement enables ‘liquid biopsies’ for metastatic melanoma

Researchers at UCLA report that they have refined a method they previously developed for capturing and analyzing cancer cells that break away from patients’ tumors and circulate in the blood. With the improvements to their device, which uses a Velcro-like nanoscale technology, they can now detect and isolate single cancer cells from patient blood samples for analysis.

Circulating tumor cells, or CTCs, play a crucial role in cancer metastasis, spreading from tumors to other parts of the body, where they form new tumors. When these cells are isolated from the blood early on, they can provide doctors with critical information about the type of cancer a patient has, the characteristics of the individual cancer and the potential progression of the disease. Doctors can also tell from these cells how to tailor a personalized treatment to a specific patient. (more…)

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Earthquakes, Glue and Grappling Hooks: Scientists Dissect the Movement of Bacteria

A team led by researchers from the UCLA Henry Samueli School of Engineering and Applied Science has discovered that microscopic bacteria have a lot in common with earthquakes — when it comes to their jolting movements.

In a new study published in the peer-reviewed Proceedings of the National Academy of Sciences, the scientists also report that a molecular “glue” produced by the bacteria to help them adhere to surfaces also acts as a sort of transportation lubricant, helping them move and organize into rudimentary social structures. These discoveries, they say, could lead to new ways to combat harmful microbes in the long term. (more…)

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New Book Traces Black Panthers’ Evolution from Local Activists to Global Anti-Imperialists

History has long denied the political genius of the Black Panther Party. At worst, its members have been cast as unconscionable criminals. At best, such seminal figures as party founders Huey Newton and Bobby Seale and early supporter Stokely Carmichael have been portrayed as outlaw folk heroes who, propelled by the progressive winds of the late 1960s, dared to take on the establishment.

But a UCLA graduate student in sociology who worked alongside former Panthers a decade ago as a community organizer in Oakland, Calif., didn’t buy the conventional wisdom. (more…)

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Survey: More Freshmen than Ever Say They Go to College to Get Better Jobs, Make More Money

The current economic situation in the United States has a major influence on first-year students’ decisions about which college to attend and is reflected in their reasons for pursuing higher education, according to the CIRP Freshman Survey, UCLA’s annual survey of the nation’s entering students at four-year colleges and universities.

The survey, part of the Cooperative Institutional Research Program (CIRP), is administered nationally by the Higher Education Research Institute (HERI) at UCLA’s Graduate School of Education and Information Studies.

Two out of three first-year students (66.6 percent) surveyed said they believe current economic conditions significantly affected their choice of college, up from 62.1 percent just two years earlier, when the question was first asked. (more…)

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Right Target, but Missing the Bulls-Eye for Alzheimer’s

UCLA researchers discover new point of attack for drug therapy

Alzheimer’s disease is the most common cause of late-life dementia. The disorder is thought to be caused by a protein known as amyloid-beta, or Abeta, which clumps together in the brain, forming plaques that are thought to destroy neurons. This destruction starts early, too, and can presage clinical signs of the disease by up to 20 years.

For decades now, researchers have been trying, with limited success, to develop drugs that prevent this clumping. Such drugs require a “target” — a structure they can bind to, thereby preventing the toxic actions of Abeta. (more…)

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