A type of onion could help the fight against antibiotic resistance in cases of tuberculosis, a UCL and Birkbeck-led study suggests.
Researchers believe the antibacterial properties extracted from the Persian shallot could increase the effects of existing antibiotic treatment. (more…)
A new class of molecules called acyldepsipeptides — ADEPs — may provide a new way to attack bacteria that have developed resistance to antibiotics. Researchers at Brown and MIT have discovered a way to increase the potency of ADEPs by up to 1,200 times. Their findings appear in the Journal of the American Chemical Society.
PROVIDENCE, R.I. [Brown University] — As concerns about bacterial resistance to antibiotics grow, researchers are racing to find new kinds of drugs to replace ones that are no longer effective. One promising new class of molecules called acyldepsipeptides — ADEPs — kills bacteria in a way that no marketed antibacterial drug does — by altering the pathway through which cells rid themselves of harmful proteins. (more…)
Study Points to Need for Interventions That Address Neighborhood Poverty
COLUMBUS, Ohio – Living in a poor neighborhood as an adolescent is linked to an increased risk of getting the sexually transmitted infection (STI) chlamydia in young adulthood, according to new research.
Ohio State University researchers analyzed data from a large national study that tracked youths over time. The analysis suggested that children who lived in poor neighborhoods during their teenage years had an almost 25 percent greater risk of having chlamydia in their early 20s – even if they themselves weren’t poor – than did teenagers living in wealthier settings. (more…)
Save the tick that bites you: it may not be the one you think
This year’s mild winter and early spring were a bonanza for tick populations in the eastern United States. Reports of tick-borne disease rose fast.
While Lyme disease is the most common tick-borne disease in the Northeast and Upper Midwest, new research results emphasize that it is not the greatest cause for concern in most Southeastern states.
The findings are published today in a paper in the journal Zoonoses and Public Health. (more…)
EAST LANSING, Mich. — Researchers at Michigan State University have shown a prebiotic may help the body’s own natural killer cells fight bacterial infection and reduce inflammation, greatly decreasing the risk of colon cancer.
Prebiotics are fiber supplements that serve as food for the trillions of tiny bacteria living in the gut. When taken, they can stimulate the growth of the “good” bacteria. The evolution of prebiotic supplements (as well as probiotics, which are actual bacteria ingested into the system) provide new therapeutic targets for researchers and physicians. (more…)
COLUMBUS, Ohio – Scientists have found why a certain type of bacteria, harmless in healthy people, is so deadly to patients with cystic fibrosis.
The bacterium, Burkholderia cenocepacia, causes a severe and persistent lung infection in patients with CF and is resistant to nearly all known antibiotics. Cystic fibrosis is a chronic disorder characterized by a buildup of mucus in the lungs and other parts of the body, and various types of lung infection are responsible for about 85 percent of deaths in these patients. (more…)
EAST LANSING, Mich. — Recent research by Michigan State University scientists has shed more light on how plants are able to cope with extreme environments.
However, the name of one of the key contributors to the work, which is detailed in the online version of the Proceedings of the National Academy of Sciences, is not listed among the paper’s authors. That’s because it’s a cluster of computers. (more…)
*University of Missouri investigators’ discovery sheds light on how plants fight off bacterial infections*
Columbia, MO — Like us, plants rely on an immune system to fight off disease. Proteins that scout out malicious bacterial invaders in the cell and communicate their presence to the nucleus are important weapons in the plant’s disease resistance strategy. Researchers at the University of Missouri recently “tapped” into two proteins’ communications with the nucleus and discovered a previously unknown level of cross talk. The discovery adds important new information about how plant proteins mediate resistance to bacteria that cause disease and may ultimately lead to novel strategies for boosting a plant’s immune system.
Special proteins in the plant, called resistance proteins, can recognize highly specific features of proteins from pathogen, called effector proteins. When a pathogen is detected, a resistance protein triggers an “alarm” that communicates the danger to the cell’s nucleus. The communication between the resistance protein and nucleus occurs through a mechanism called a signaling pathway. (more…)
