Tag Archives: urinary tract infections

Increase in antibiotic-resistant bacteria hinders treatment of kidney infections

Researchers recommended development of new medications and new guidelines for treatment

The increase in illnesses and deaths linked to medication-resistant bacteria has been well-documented by researchers and received extensive public attention in recent years. Now, UCLA-led research shows how these bacteria are making it more difficult to treat a common but severe kidney infection. (more…)

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More Power to the Cranberry: Study Shows the Juice is Better than Extracts at Fighting Bacterial Infections

With scientific evidence now supporting the age-old wisdom that cranberries, whether in sauce or as juice, prevent urinary tract infections, people have wondered if there was an element of the berry that, if extracted and condensed, perhaps in pill form, would be as effective as drinking the juice or eating cranberry sauce. A new study from researchers at Worcester Polytechnic Institute helps to answer that question.

The study tested proanthocyanidins or PACs, a group of flavonoids found in cranberries.  Because they were thought to be the ingredient that gives the juice its infection-fighting properties, PACs have been considered a hopeful target for an effective extract. The new WPI report, however, shows that cranberry juice, itself, is far better at preventing biofilm formation, which is the precursor of infection, than PACs alone. The data is reported in the paper “Impact of Cranberry Juice and Proanthocyanidins on the Ability of Escherichia coli to Form Biofilms,” which will be published on-line, ahead of print, Oct. 31, 2011, by the journal Food Science and Biotechnology. (more…)

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Vaccine for Urinary Tract Infections is One Step Closer

*Study sheds light on what E. coli genes are doing inside the body during infection* 

E. coli bacteria. Image credit: Amy Simms, Ph.D

ANN ARBOR, Mich. Urinary tract infections are a painful, recurring problem for millions of women. They are also getting more dangerous as bacteria develop resistance to the most common treatments.

Scientists from the University of Michigan have moved one step closer to a vaccine that could prevent a majority of urinary tract infections, which are caused by E. coli bacteria. Using a genetic technique rarely used to look at infections in human hosts, the researchers studied how the E. coli bacteria operate and discovered key differences between how the bacteria’s genes behave in women and how they behave in mice used in experiments.

Their findings, published online Nov. 11 in PLoS Pathogens, could lead to developments that would save billions in health care costs and millions of doctors’ visits and hospitalizations from urinary tract infections each year. (more…)

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Cranberry Juice Shows Promise Blocking Staph Infections

WORCESTER, Mass. – Expanding their scope of study on the mechanisms of bacterial infection, researchers at Worcester Polytechnic Institute (WPI) have reported the surprise finding from a small clinical study that cranberry juice cocktail blocked a strain of Staphylococcus aureus (S. aureus) from beginning the process of infection. (more…)

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