Tag Archives: bacteria genes

Vaccine for Urinary Tract Infections is One Step Closer

*Study sheds light on what E. coli genes are doing inside the body during infection* 

E. coli bacteria. Image credit: Amy Simms, Ph.D

ANN ARBOR, Mich. Urinary tract infections are a painful, recurring problem for millions of women. They are also getting more dangerous as bacteria develop resistance to the most common treatments.

Scientists from the University of Michigan have moved one step closer to a vaccine that could prevent a majority of urinary tract infections, which are caused by E. coli bacteria. Using a genetic technique rarely used to look at infections in human hosts, the researchers studied how the E. coli bacteria operate and discovered key differences between how the bacteria’s genes behave in women and how they behave in mice used in experiments.

Their findings, published online Nov. 11 in PLoS Pathogens, could lead to developments that would save billions in health care costs and millions of doctors’ visits and hospitalizations from urinary tract infections each year. (more…)

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