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Human Cognition Depends Upon Slow-Firing Neurons

By Guest PostFebruary 26, 2013Sciencealzheimer's disease, amy arnsten, any sensory stimulation, brain circuits, clear thinking, cognitive deficits, dementia, disease, Environment, firing of neurons, glutamate signaling regulate, good mental health, hallmark, human cognition, john krystal, mathematical models, medicine, mental sketch pad, min wang, molecular basis, nao j gamo, neuronal firing, new york university, nmda nr2b receptors, prefrontal cortex, receptors, schizophrenia, street drug, types of nmda, xiao jing wang, yale neurobiologist, yale school, yang yang

Good mental health and clear thinking depend upon our ability to store and manipulate thoughts on a sort of “mental sketch pad.” In a new study, Yale School of Medicine researchers describe the molecular basis of this ability — the hallmark of human cognition — and describe how a breakdown of the system contributes to diseases such as schizophrenia and Alzheimer’s disease.

“Insults to these highly evolved cortical circuits impair the ability to create and maintain our mental representations of the world, which is the basis of higher cognition,” said Amy Arnsten, professor of neurobiology and senior author of the paper published in the Feb. 20 issue of the journal Neuron. (more…)

‘Most Verbose’: Meet Microsoft’s Original MVP

By Guest PostFebruary 26, 2013Technologybroadband, calvin hsia, calvin list, compuserve forum, database, developer division, Facebook, feedback, foxpro, hawaii, Microsoft, microsoft ceo, microsoft employee, modem, most verbose, most verbose people, mvp list, original mvp, professional program, redmond, sde, software development engineer, steve ballmer, Twitter, verbosity, visual studio

Twenty years ago, Calvin Hsia created a list of the “Most Verbose People” on a CompuServe forum that became Microsoft’s Most Valuable Professional program.

REDMOND, Wash. – It’s 1993, and you need technical support. Who you gonna call?

Most techies at the time would plug in their modems and dial up CompuServe. In the days before Twitter, Facebook and broadband, CompuServe’s forums were a gathering place for geeks to talk shop and get answers to burning questions. (more…)

comScore Releases the “2013 Mobile Future in Focus” Report

By Guest PostFebruary 25, 2013Technologydigital media consumption, key mobile trends, market dynamics, mobile future, mobile networks, multi platform paradigm

Report Features Insights on Key Mobile Trends from 2012 and What They Mean for the Year Ahead

RESTON, VA, February 25, 2013– comScore, Inc., a global leader in digital measurement and analytics, today released the 2013 Mobile Future in Focus report. This annual report examines the U.S. mobile and connected device landscape in 2012, highlighting trends that have shaped mobile media consumption and shifted market dynamics across mobile networks, platforms, and OEMs. The report also includes key mobile market insights from the United Kingdom, France, Germany, Spain, Italy, Canada, and Japan. (more…)

Malawi’s Bountiful Harvests and Healthier Children

By Guest PostFebruary 25, 2013Sciencechildren of ekwendi, crop diversity, crop model simulations, northern malawi, soil health

In Malawi, the fields are full – and so are the children.

Through research led by Michigan State University, crop yields have increased dramatically. The children of Ekwendi, Malawi, also have gained weight and are taller. These improvements bring smiles to Sieglinde Snapp, MSU ecologist, and other researchers who have worked in Malawi for many years. (more…)

Researchers Propose New Way to Probe Earth’s Deep Interior

By Guest PostFebruary 25, 2013Scienceafu lin, amherst college, atoms, austin, building blocks, central core, characteristics, characteristics of mantle, chemical properties, composition, deep earth, earth, earth rotation axis, electromagnetism, electron spin density, electrons, elusive fifth force, fifth force, geoelectrons, geological layer, geomagnetic field, gravitational attraction, gravity, interior, jung fu, larry hunter, magnetic interaction, mantle, Nature, neutrons, new technique, outer crust, protons, researchers, spin, spin directions, spin spin interaction, strong nuclear forces, subatomic particles, university of texas

AUSTIN, Texas — Researchers from Amherst College and The University of Texas at Austin have described a new technique that might one day reveal in higher detail than ever before the composition and characteristics of the deep Earth.

There’s just one catch: The technique relies on a fifth force of nature (in addition to gravity, the weak and strong nuclear forces and electromagnetism) that has not yet been detected, but which some particle physicists think might exist. Physicists call this type of force a long-range spin-spin interaction. If it does exist, this exotic new force would connect matter at Earth’s surface with matter hundreds or even thousands of kilometers below, deep in Earth’s mantle. In other words, the building blocks of atoms—electrons, protons, and neutrons—separated over vast distances would “feel” each other’s presence. The way these particles interact could provide new information about the composition and characteristics of the mantle, which is poorly understood because of its inaccessibility. (more…)

Understanding Angelman syndrome: Study in Mice Yields Angelman Advance

By Guest PostFebruary 25, 2013Scienceangelman syndrome, gene defect, neurological signaling, neurotrophic factor

In the journal PLoS Biology, a team of scientists reports experiments showing how the gene defect of Angelman syndrome disrupts neurological processes that may be needed for memory and learning. In tests in mice, the team showed that a novel compound could restore the healthy processes. (more…)

Mutant Champions Save Imperiled Species from Almost-Certain Extinction

By Guest PostFebruary 25, 2013Scienceantibiotics, bacterium, benjamin kerr, changing environments, climate change, disease causing bacteria, e coli, environmental changes, environmental deterioration, escherichia coli, eth zurich, evolutionary adaptations, evolutionary rescue, extinction, extinction bullet, genes, genetic engineering, haley lindsey, heavy metals, high concentration environment, human caused changes, imperiled species, insects, jenna gallie, lower concentration, mutant champions, number of factors, overfishing, pesticides, population, populations of microorganisms, rapid rates, relay team, seattle, susan taylor, university of washington

Species facing widespread and rapid environmental changes can sometimes evolve quickly enough to dodge the extinction bullet. Populations of disease-causing bacteria evolve, for example, as doctors flood their “environment,” the human body, with antibiotics. Insects, animals and plants can make evolutionary adaptations in response to pesticides, heavy metals and overfishing.

Previous studies have shown that the more gradual the change, the better the chances for “evolutionary rescue” – the process of mutations occurring fast enough to allow a population to avoid extinction in changing environments. One obvious reason is that more individuals remain alive when change is gradual or moderate, meaning there are more opportunities for a winning mutation to emerge. (more…)

Climate Change is not an All-or-Nothing Proposition, Researcher Says

By Guest PostFebruary 25, 2013Environmentamericans, climate, climate change, climate model, climate research, data accumulates, earth, extreme disasters, high tides, human difficulty, human nature, mark berliner, mitigation strategies, model, negative impacts, ohio state university, periodic floods, statistician

BOSTON — An Ohio State University statistician says that the natural human difficulty with grasping probabilities is preventing Americans from dealing with climate change.

In a panel discussion at the American Association for the Advancement of Science meeting on Feb. 15, Mark Berliner said that an aversion to statistical thinking and probability is a significant reason that we haven’t enacted strategies to deal with climate change right now. (more…)

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