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Multi-Toxin Biotech Crops Not Silver Bullets, UA Scientists Warn

By Guest PostMarch 31, 2013Environment, Natureafrica, bacillus thuringiensis, bacterium, biotech crops, bruce tabashnik, bt, bt cotton, bt toxin, caterpillars, cirad, corn earworm, cotton bollworm, cry1, cry1ac, cry2 toxins, cry2ab, entomologists, Environment, epa, genetically engineered crops, helicoverpa zea, insecticide sprays, multi toxin, one toxin, pest control, pest killing proteins, pyramid strategy, silver bullets, simulation models, two toxin, university of arizona, US, yves carriere

The popular new strategy of planting genetically engineered crops that make two or more toxins to fend off insect pests rests on assumptions that don’t always apply, UA researchers have discovered. Their study helps explain why one major pest is evolving resistance much faster than predicted and offers ideas for more sustainable pest control.

A strategy widely used to prevent pests from quickly adapting to crop-protecting toxins may fail in some cases unless better preventive actions are taken, suggests new research by University of Arizona entomologists published in the Proceedings of the National Academy of Sciences.

Corn and cotton have been genetically modified to produce pest-killing proteins from the bacterium Bacillus thuringiensis, or Bt for short. Compared with typical insecticide sprays, the Bt toxins produced by genetically engineered crops are much safer for people and the environment, explained Yves Carrière, a professor of entomology in the UA College of Agriculture and Life Sciences who led the study. (more…)

Smarter Toxins Help Crops Fight Resistant Pests

By Guest PostOctober 11, 2011Scienceb rogers leonard, bacillus thuringiensis, bacterium, beneficial insects, bruce tabashnik, bt, bt cotton, bt toxins, cadherin, cadherin mutations, caterpillars, change in molecular structure, crop protecting proteins, david heckel, fangneng huang, genetic engineering, Germany, jena, lady bugs, manduca sexta, max planck institute for chemical ecology, mukti ghimire, pectinophora gossypiella, pests, pink bollworm, rna interference, tobacco hornworm

*A slight change in molecular structure introduced by genetic engineering gives crop-protecting proteins called Bt toxins a new edge in overcoming resistance of certain pests, a UA-led team of researchers reports in Nature Biotechnology.*

One of the most successful strategies in pest control is to endow crop plants with genes from the bacterium Bacillus thuringiensis, or Bt for short, which code for proteins that kill pests attempting to eat them.

But insect pests are evolving resistance to Bt toxins, which threatens the continued success of this approach. In the current issue of Nature Biotechnology, a research team led by UA Professor Bruce Tabashnik reports the discovery that a small modification of the toxins’ structure overcomes the defenses of some major pests that are resistant to the natural, unmodified Bt toxins. (more…)

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Multi-Toxin Biotech Crops Not Silver Bullets, UA Scientists Warn

Smarter Toxins Help Crops Fight Resistant Pests