Tag Archives: rna interference

Biologists Turn Back the Clock to Understand Evolution of Sex Differences

Battles of sexes shown to spur adaptive sex differences

Sex differences account for some of the most of the spectacular traits in nature: the wild colours of male guppies, the plumage of peacocks, tusks on walruses and antlers on moose. Sexual conflict – the battle between males and females over mating – is thought to be a particularly potent force in driving the evolution of traits that differ in males and females.

However, the genetic processes responsible for producing such traits are not well understood, nor how they evolved from their simpler less elaborate ancestral forms. We tend to assume that each tiny step in evolution is an advantage. But are they really? (more…)

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Smarter Toxins Help Crops Fight Resistant Pests

*A slight change in molecular structure introduced by genetic engineering gives crop-protecting proteins called Bt toxins a new edge in overcoming resistance of certain pests, a UA-led team of researchers reports in Nature Biotechnology.*

One of the most successful strategies in pest control is to endow crop plants with genes from the bacterium Bacillus thuringiensis, or Bt for short, which code for proteins that kill pests attempting to eat them.

But insect pests are evolving resistance to Bt toxins, which threatens the continued success of this approach. In the current issue of Nature Biotechnology, a research team led by UA Professor Bruce Tabashnik reports the discovery that a small modification of the toxins’ structure overcomes the defenses of some major pests that are resistant to the natural, unmodified Bt toxins. (more…)

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U of T researcher discovers key protein involved in DNA repair

*Discovery gives insight into the way cells protect their own genetic material* 

In a groundbreaking study, U of T researchers including Professors Daniel Durocher, AnneClaude Gingras and Frank Sicheri have uncovered a protein called OTUB1 that blocks DNA damage in the cell—a discovery that may lead to the development of strategies to improve some cancer therapies.

(more…)

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