Tag Archives: clinical trial

Mayo Clinic’s clinical trial matching project sees higher enrollment in breast cancer trials through use of artificial intelligence

ROCHESTER, Minn – 08 Mar 2018: Mayo Clinic and IBM Watson Health (NYSE: IBM) today unveiled results from early use of the Watson for Clinical Trial Matching, an IBM cognitive computing system. Use of this system in the Mayo Clinic oncology practice has been associated with more patients enrolled in Mayo’s breast cancer clinical trials. (more…)

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UCLA to develop ‘brain prosthesis’ to help brain-injured patients recover memory

As part of a major federal initiative, UCLA has been awarded $15M to create a wireless, implantable device that could restore memory to millions

UCLA has been tapped by the Defense Advanced Research Projects Agency to spearhead an innovative project aimed at developing a wireless, implantable brain device that could help restore lost memory function in individuals who have suffered debilitating brain injuries and other disorders. (more…)

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In hairless man, arthritis drug spurs hair growth — lots of it

A man with almost no hair on his body has grown a full head of it after a novel treatment by doctors at Yale University.

There is currently no cure or long-term treatment for alopecia universalis, the disease that left the 25-year-old patient bare of hair. This is the first reported case of a successful targeted treatment for the rare, highly visible disease. (more…)

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Preliminary clinical trial shows great promise for new multiple sclerosis treatment

Female hormone estriol reduces relapse rate by nearly 50 percent, UCLA neurologist reports

A study conducted by Dr. Rhonda Voskuhl, a UCLA neurologist, shows that combining estriol, a female hormone, with Copaxone, a medication currently used to treat multiple sclerosis, reduced the relapse rate of MS by nearly 50 percent with only one year of treatment.  (more…)

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Good Vibrations: Mediating Mood Through Brain Ultrasound

Ultrasound vibrations applied to the brain may affect mood, UA researchers have discovered. The finding potentially could lead to new treatments for psychological and psychiatric disorders.

University of Arizona researchers have found in a recent study that ultrasound waves applied to specific areas of the brain appear able to alter patients’ moods. The discovery has led the scientists to conduct further investigations with the hope that this technique could one day be used to treat conditions such as depression and anxiety.

Dr. Stuart Hameroff, professor emeritus of the UA’s departments of anesthesiology and psychology and director of the UA’s Center for Consciousness Studies, is lead author on the first clinical study of brain ultrasound, which was published in the journal Brain Stimulation. (more…)

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UCLA Study Shows Promise, Offers Hope for Brain Hemorrhage Patients

Minimally invasive surgery may benefit patients previously deemed hopeless

A new endoscopic surgical procedure has been shown to be safer and to result in better outcomes than the current standard medical treatment for patients who suffer strokes as a result of brain hemorrhages, UCLA neurosurgeons have announced.

The findings from their potentially groundbreaking, randomized, controlled phase 2 clinical trial, which was conducted at multiple medical centers, were presented last week at the International Stroke Conference in Honolulu. (more…)

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Gold Nanoparticle Prostate Cancer Treatment Found Safe in Dogs, MU Study Shows

New treatment may have fewer side effects than traditional cancer therapy

COLUMBIA, Mo. ­— Currently, large doses of chemotherapy are required when treating certain forms of cancer, resulting in toxic side effects. The chemicals enter the body and work to destroy or shrink the tumor, but also harm vital organs and drastically affect bodily functions. Now, scientists at the University of Missouri have proven that a new form of prostate cancer treatment that uses radioactive gold nanoparticles, and was developed at MU, is safe to use in dogs. Sandra Axiak-Bechtel, an assistant professor in oncology at the MU College of Veterinary Medicine, says that this is a big step for gold nanoparticle research.

“Proving that gold nanoparticles are safe to use in the treatment of prostate cancer in dogs is a big step toward gaining approval for clinical trials in men,” Axiak-Bechtel said. “Dogs develop prostate cancer naturally in a very similar way as humans, so the gold nanoparticle treatment has a great chance to translate well to human patients.” (more…)

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Doctors Wary of Studies Funded by Pharmaceutical Industry, Study Shows

Physicians are about half as willing to prescribe drugs tested in pharmaceutical-industry funded trials than those in NIH-funded studies, a new study finds.

Physicians are less likely to trust the results of clinical trials when they know those trials were funded by pharmaceutical companies, regardless of the quality of the research, a recent study in the New England Journal of Medicine shows.

The study, led by Dr. Aaron Kesselheim of the Harvard Medical School in Boston and co-authored by University of Arizona associate professor of law Christopher Robertson, evaluated physicians’ confidence in the results of drug trials conducted with a high, medium or low level of methodological rigor. It then looked at how their confidence in those same results changed when a trial’s funding source was revealed as either the National Institutes of Health or a company in the pharmaceutical industry, versus when no funding source was disclosed. (more…)

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