Tag Archives: placebo

Preliminary clinical trial shows great promise for new multiple sclerosis treatment

Female hormone estriol reduces relapse rate by nearly 50 percent, UCLA neurologist reports

A study conducted by Dr. Rhonda Voskuhl, a UCLA neurologist, shows that combining estriol, a female hormone, with Copaxone, a medication currently used to treat multiple sclerosis, reduced the relapse rate of MS by nearly 50 percent with only one year of treatment.  (more…)

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Good Vibrations: Mediating Mood Through Brain Ultrasound

Ultrasound vibrations applied to the brain may affect mood, UA researchers have discovered. The finding potentially could lead to new treatments for psychological and psychiatric disorders.

University of Arizona researchers have found in a recent study that ultrasound waves applied to specific areas of the brain appear able to alter patients’ moods. The discovery has led the scientists to conduct further investigations with the hope that this technique could one day be used to treat conditions such as depression and anxiety.

Dr. Stuart Hameroff, professor emeritus of the UA’s departments of anesthesiology and psychology and director of the UA’s Center for Consciousness Studies, is lead author on the first clinical study of brain ultrasound, which was published in the journal Brain Stimulation. (more…)

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The Placebo Effect Goes Beyond Humans, UF Researchers Find

GAINESVILLE, Fla. — Rats and humans have at least one thing in common: They both react the same way to a placebo, according to a new University of Florida study.

“That was the big finding — that the animals that expected pain relief actually got pain relief when you gave them an inert substance,” said co-author John Neubert, a pain specialist and an associate professor with the UF College of Dentistry department of orthodontics. “It helps validate our model that what we do in the rats, we believe, is a good representation of what’s being seen in humans.”

The investigation of placebo effects might lead to the identification of new therapeutic targets in the brain and of novel treatment strategies for a variety of health conditions. (more…)

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Ancient Foot Massage Technique May Ease Cancer Symptoms

EAST LANSING, Mich. — A study led by a Michigan State University researcher offers the strongest evidence yet that reflexology – a type of specialized foot massage practiced since the age of pharaohs – can help cancer patients manage their symptoms and perform daily tasks.

Funded by the National Cancer Institute and published in the latest issue of Oncology Nursing Forum, it is the first large-scale, randomized study of reflexology as a complement to standard cancer treatment, according to lead author Gwen Wyatt, a professor in the College of Nursing. (more…)

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Groundbreaking Research Paves Way for HIV Prevention Drug Approval

For the first time, the U.S. Food and Drug Administration is considering approving a drug that helps prevent someone from acquiring HIV. It’s called Truvada, and has been approved for use since 2004 to treat infected people.

Now it has been shown to protect healthy people who are exposed to HIV. The UW’s International Clinical Research Center, within the Department of Global Health, played a key role in examining the drug’s effectiveness for HIV prevention.

Researchers Connie Celum and Jared Baeten led a study, published this week in the New England Journal of Medicine, of pre-exposure prophylaxis among heterosexual couples in Kenya and Uganda. One partner had HIV (and was not yet eligible for HIV treatment) and the other partner did not have HIV. Uninfected partners were given either Truvada or Tenofovir (both antiretroviral drugs) or a placebo. (more…)

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Soy and Menopause

*Large-scale study finds soy may alleviate hot flashes in menopause*

In the most comprehensive study to date to examine the effects of soy on menopause, researchers have found that two daily servings of soy can reduce the frequency and severity of hot flashes by up to 26 percent, compared to a placebo.

The findings, published in Menopause: The Journal of the North American Menopause Association, reviewed 19 previous studies that examined more than 1,200 women. (more…)

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What Makes Ticks Tick?

Durland Fish has researched ticks and their associated diseases for decades. A professor in the Division of Epidemiology of Microbial Diseases at the Yale School of Public Health, he has, among other things, contributed to the discovery that the bacterium that causes Lyme disease has European ancestry and that the disease, once nearly eradicated in North America, roared back with reforestation. More recently he helped develop a Lyme disease “app” for the iPhone and other Apple devices that provides users with detailed information about tick populations in any given area in the United States and even comes with a video on how to safely remove a tick. He has also worked on mosquito-borne West Nile virus and dengue fever. Students selected Fish as the school’s mentor of the year in 2010. (more…)

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Breast Tenderness Following Combo Hormone Therapy Linked To Increased Breast Density

*Study examines biology underlying link between tenderness, cancer risk*

Post-menopausal women who experience breast tenderness after starting combination hormone therapy have a higher risk of breast cancer than women who don’t, a study by researchers with UCLA’s Jonsson Comprehensive Cancer Center has shown. One reason for this, they now say, may be that these women’s breasts are becoming more dense.

Such new-onset tenderness was found to be more pronounced after the start of combination estrogen-and-progestin therapy than with estrogen therapy alone. The link between new-onset tenderness and changes in breast density also was more pronounced in women on combination therapy, said the study’s first author, Dr. Carolyn Crandall, a UCLA professor of general internal medicine and a scientist with the Jonsson Cancer Center. (more…)

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