Tag Archives: placebo response

Deconstructing the placebo response: Why does it work in treating depression?

UCLA study suggests patients’ responses are closely tied to their expectations

In the past three decades, the power of placebos has gone through the roof in treating major depressive disorder. In clinical trials for treating depression over that period of time, researchers have reported significant increases in patient’s response rates to placebos — the simple sugar pills given to patients who think that it may be actual medication. (more…)

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The Placebo Effect Goes Beyond Humans, UF Researchers Find

GAINESVILLE, Fla. — Rats and humans have at least one thing in common: They both react the same way to a placebo, according to a new University of Florida study.

“That was the big finding — that the animals that expected pain relief actually got pain relief when you gave them an inert substance,” said co-author John Neubert, a pain specialist and an associate professor with the UF College of Dentistry department of orthodontics. “It helps validate our model that what we do in the rats, we believe, is a good representation of what’s being seen in humans.”

The investigation of placebo effects might lead to the identification of new therapeutic targets in the brain and of novel treatment strategies for a variety of health conditions. (more…)

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