*Study examines biology underlying link between tenderness, cancer risk*
Post-menopausal women who experience breast tenderness after starting combination hormone therapy have a higher risk of breast cancer than women who don’t, a study by researchers with UCLA’s Jonsson Comprehensive Cancer Center has shown. One reason for this, they now say, may be that these women’s breasts are becoming more dense.
Such new-onset tenderness was found to be more pronounced after the start of combination estrogen-and-progestin therapy than with estrogen therapy alone. The link between new-onset tenderness and changes in breast density also was more pronounced in women on combination therapy, said the study’s first author, Dr. Carolyn Crandall, a UCLA professor of general internal medicine and a scientist with the Jonsson Cancer Center. (more…)