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Questions for Brandon Marshall: Predicting outcomes of HIV efforts in NYC

By Guest PostMarch 22, 2014Healthaffordable care act, brandon marshall, brown university, columbia university, david orenstein, drug user, high impact, hiv care, hiv efforts, hiv epidemic, hiv incidence, hiv treatment, hiv-positive, new york city, nyc, outcome, predictive computer model

New York City continues to battle an HIV epidemic, including among drug users. There are many possible interventions. Researchers have developed a sophisticated predictive computer model to help policymakers figure out which interventions, or combinations of interventions, would have the most meaningful impact.

Brandon Marshall, assistant professor of epidemiology at Brown University, has led the simulation effort ever since he was a postdoctoral scholar at Columbia University. In a new paper in the March edition of the journal Health Affairs a team from Brown and Columbia published the results of the simulation, which projects that New York can significantly reduce new infections among drug users by 2040 by implementing certain combinations of interventions. Marshall spoke with David Orenstein about what the predictive computer model shows. (more…)

HIV plus HPV leads to increased anal cancer risk in men

By Guest PostDecember 18, 2013Healthanal cancer risk, cancer prevention strategies, dorothy j wiley, hilary hsu, hiv infection characteristics, hiv plus hpv, hiv positive men, hiv treatment, human papillomavirus, in men, otoniel martinez maza, roger detels, sex with men, tobacco, uninfected men, united states

Human papillomavirus, or HPV, which can cause cervical cancer in women, is also known to cause anal cancer in both women and men. Now, a study led by researchers at the UCLA School of Nursing has found that older HIV-positive men who have sex with men are at higher risk of becoming infected with the HPVs that most often cause anal cancer.

The researchers also report that smoking increases the risk of infection with specific types of HPV among both HIV-infected and uninfected older men by up to 20 percent. This is the first large U.S. study of a group of HIV-infected and uninfected men between the ages of 40 and 69 who have sex with men. Study participants were examined twice a year for up to 25 years. (more…)

Political strife undermines HIV treatment

By Guest PostMarch 27, 2013Health, Politicsaids reviews, ampath, antiretroviral therapy, brown university, conflict related disruption, elections, haart, highly active, hiv epidemics, hiv treatment, jane carter, Kenya, kenyan citizens, marita mann, moi university, policymakers, political conflict, political strife, political violence, post strife treatment, providence, rami kantor, sylvester kimaiyo, the miriam hospital, viral load

Among other tragedies in countries with HIV epidemics, political violence can have the additional long-term consequence of an increase in viral resistance to treatment and HIV treatment failure, say the authors of a new paper in AIDS Reviews. The researchers, who have studied post-strife treatment failure and resistance in Kenya, argue that officials and health care providers need to study and prepare for how violence disrupts antiretroviral treatment and complicates the epidemic.

PROVIDENCE, R.I. [Brown University] — As Kenyan citizens negotiated the tensions following the March 4 nationwide elections, memories of the violence that followed the December 2007 vote weighed heavily for many reasons. Among those in any nation with an HIV epidemic, argue authors of a new paper in AIDS Reviews, should be the long-term damage that political conflict can do to public health by disrupting treatment and thereby promoting resistance to antiretroviral drugs and treatment failure. (more…)

Groundbreaking Research Paves Way for HIV Prevention Drug Approval

By Guest PostJuly 15, 2012Healthafrica, antiretroviral drugs, connie celum, fda, hiv, hiv infection, hiv prevention, hiv treatment, hiv vaccine, hiv-positive, jared baeten, Kenya, kenya puppets, nelly mugo, partners prep, placebo, prevention drug, tenofovir, thika, truvada, uganda

For the first time, the U.S. Food and Drug Administration is considering approving a drug that helps prevent someone from acquiring HIV. It’s called Truvada, and has been approved for use since 2004 to treat infected people.

Now it has been shown to protect healthy people who are exposed to HIV. The UW’s International Clinical Research Center, within the Department of Global Health, played a key role in examining the drug’s effectiveness for HIV prevention.

Researchers Connie Celum and Jared Baeten led a study, published this week in the New England Journal of Medicine, of pre-exposure prophylaxis among heterosexual couples in Kenya and Uganda. One partner had HIV (and was not yet eligible for HIV treatment) and the other partner did not have HIV. Uninfected partners were given either Truvada or Tenofovir (both antiretroviral drugs) or a placebo. (more…)

Tag Archives: hiv treatment

Questions for Brandon Marshall: Predicting outcomes of HIV efforts in NYC

HIV plus HPV leads to increased anal cancer risk in men

Political strife undermines HIV treatment

Groundbreaking Research Paves Way for HIV Prevention Drug Approval