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Mystery of the mutant polyomavirus

By Guest PostJuly 7, 2013Health, Scienceaaron derdowski, astrocytes, bethany ohara, brain glial cells, brown university, carbohydrate, crystal structure, DNA, gretchen gee, infectious, jc polyomavirus, lstc, luisa ströh, melissa maginnis, mutant form, mutant polyomavirus, myelin, mystery, non infection, oligodendrocytes, pathogen, pml, progressive multifocal leukoencephalopathy, thilo stehle, university of tübingen, ursula neu, vanderbilt university, virus, walter atwood, wild type, xray crystallography

A new study shows that common mutant forms of the deadly JC polyomavirus are not responsible for the pathogen’s main attack, which causes a brain-damaging disease in immunocompromised patients called progressive multifocal leukoencephalopathy. But that finding raises the ominous question of what the mutants might be up to instead.

PROVIDENCE, R.I. [Brown University] — The JC polyomavirus is clearly opportunistic. It infects half the population but lethally destroys brain tissue only in immunocompromised patients — and it may be outright sneaky, too. Even as a new research paper allays fears that common mutant forms of the virus are the ones directly responsible for the disease’s main attack, that same finding raises new questions about what the mutants are doing instead. (more…)

Studying meteorites may reveal Mars’ secrets of life

By Guest PostMay 24, 2013Scienceage old question, alterations, Antarctica, billion years ago, data from meteorites, earth, geochemical processes, mars, michael velbel, michigan state university, miller range, mineralogical studies, mystery, nakhlite meteorite, rover data, secrets of life, solar system, studying meteorites

In an effort to determine if conditions were ever right on Mars to sustain life, a team of scientists, including a Michigan State University professor, has examined a meteorite that formed on the red planet more than a billion years ago.

And although this team’s work is not specifically solving the mystery, it is laying the groundwork for future researchers to answer this age-old question. (more…)

Astronomers find evidence of hungry young exoplanets

By Guest PostMay 22, 2013Scienceasteroids, astronomer, complex, disk material, distorted formation, evidence, Galaxy, hungry young exoplanets, mystery, planetary childhood, planets, stefan kraus, the mechanics, university of exeter, v1247 orionis, weird

While astronomers now know that exoplanets are exceedingly common in the galaxy, the mechanics by which they are formed aren’t well understood. Planetary childhood remains a mystery.

Young stars start out with a massive disk of gas and dust that over time, astronomers think, either diffuses away or coalesces into planets and asteroids.

“The speculation is that as planets form they clear out a region of gas and dust around them, forming a telltale ‘gap’ in the disk”, said Stefan Kraus, from Physics and Astronomy at the University of Exeter. (more…)

Yale Researchers Identify Salt as a Trigger of Autoimmune Diseases

By Guest PostMarch 14, 2013Healthautoimmune diseases, autoimmune encephalomyelitis, aviv regev, david hafler, destructive immune system, dietary salt, disease, dominik mueller, Environment, function, gene, Germany, hallmark of autoimmunity, high salt content, hypertension, immune cell, low fat diet, low salt, molecular circuitry, ms, multiple sclerosis, mystery, Nature, pathogenic th17 cells, prime suspect, sub-saharan africa, t helper 17, th17 cell, vijay kuchroo

For the past few decades, health officials have been reporting increases in the incidence of autoimmune diseases such as multiple sclerosis (MS). Now researchers at Yale Medical School, Harvard Medical School and the Broad Institute have identified a prime suspect in the mystery — dietary salt.

In the March 6 issue of the journal Nature, Yale researchers showed that salt can induce and worsen pathogenic immune system responses in mice and that the response is regulated by genes already implicated in a variety of autoimmune diseases. (more…)

Tag Archives: mystery

Mystery of the mutant polyomavirus

Studying meteorites may reveal Mars’ secrets of life

Astronomers find evidence of hungry young exoplanets

Yale Researchers Identify Salt as a Trigger of Autoimmune Diseases