Researchers led by Matt Sullivan at the UA are among the first to dive into the world of viruses drifting through the world’s oceans.
Surrounded by the deep blue of the Pacific Ocean stretching from horizon to horizon, a lonely dot is glinting in the sun. It is the aluminum hull of a sailboat, a 118-foot schooner with white sails billowing from two masts.
On the deck, crewmembers and scientists are milling about. Commands are flying back and forth, and soon a strange contraption consisting of tubes clustered around an array of sensors dangling from a crane is lowered into the water, until it disappears in the clear blue depths. (more…)
An international team of researchers has discovered 13 new regions of the genome associated with the timing of menopause.
These genes shed light on the biological pathways involved in reproductive lifespan and will provide insights into conditions connected to menopause, such as breast cancer and heart disease.
Menopause is a major hormonal change that affects most women when they are in their early 50s. The timing of menopause can have a huge impact on fertility, as well as influencing the risk of a range of common diseases such as breast cancer. It has been known for some time that genetic factors influenced the onset of menopause, however until recently very few genes had been identified.
In the new study, published in the journal Nature Genetics on 22 January 2012, Dr Anna Murray, University of Exeter, Peninsula College of Medicine and Dentistry (PCMD) Dr John Perry, PCMD and WTCHG, University of Oxford, and dozens of international collaborators, examined the genomes of over 50,000 women. They identified 13 novel gene regions associated with menopause onset, and confirmed four previously identified. Most of the 17 regions include genes related to DNA damage/repair or the immune system, whilst others are linked to hormonal regulation. (more…)
*Anatomically modern humans interbred with more archaic hominin forms even before they migrated out of Africa, a UA-led team of researchers has found.*
It is now widely accepted that anatomically modern humans of the species Homo sapiens originated in Africa and eventually spread throughout the world. Ancient DNA recovered from fossil Neanderthal bones suggests they interbred with more archaic hominin forms once they had left their evolutionary cradle for the cooler climates of Eurasia, but whether they exchanged genetic material with other, now extinct archaic hominin varieties in Africa remained unclear.
UCLA life scientists and colleagues have produced one of the first high-resolution genetic maps for African American populations. A genetic map reveals the precise locations across the genome where DNA from a person’s father and mother have been stitched together through a biological process called “recombination.” This process results in new genetic combinations that are then passed on to the person’s children.
The new map will help disease geneticists working to map genetic diseases in African Americans because it provides a more accurate understanding of recombination rates among that population, said the senior author of the research, John Novembre, a UCLA assistant professor of ecology and evolutionary biology and of bioinformatics. The map could help scientists learn the roots of these diseases and discover genes that play a key role in them. (more…)
*Cycle enables marine phytoplankton to use carbon and nitrogen from their environment*
Scientists have discovered that marine diatoms, tiny phytoplankton abundant in the sea, have an animal-like urea cycle, and that this cycle enables the diatoms to efficiently use carbon and nitrogen from their environment. (more…)
*New map of the genetic code of endangered orangutans yields important new conservation tools and insights into evolution*
For the first time, scientists have mapped the genome–the genetic code–of orangutans. This new tool may be used to support efforts to maintain the genetic diversity of captive and wild orangutans. The new map of the orangutan genome may also be used to help improve our understanding of the evolution of primates, including humans.
Partially funded by the National Science Foundation, the orangutan study appears in the Jan. 27 issue of Nature. It was conducted by an international team of scientists led by Devin P. Locke of the Genome Center at Washington University. (more…)
