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First Atomic-Scale Real-Time Movies of Platinum Nanocrystal Growth in Liquids

By Guest PostApril 23, 2012Sciencealex zettl, alivisatos zettl collaboration, anisotropic particle, atomic scale, berkeley lab, crystallographic direction, daniel hellebusch, DNA, electron beam, electron microscope, gold tem mesh, grapheme, graphene liquid cells, growth, growth trajectory, jeong yong lee, jong min yuk, jungwon park, kwanpyo kim, liquid, lynn yarris, membrane, metal, michael crommie, movie, nanocrystal, nanometer scale, nanoparticle growth, ncem, paul alivisatos, peter ercius, platinum nanocrystal, protein, real-time, solution, subnanometer resolution, tem grid, transmission electron microscope, university of california

Berkeley Scientists Create Graphene Liquid Cells for Electron Microscopy Studies of Nanocrystal Formation

They won’t be coming soon to a multiplex near you, but movies showing the growth of platinum nanocrystals at the atomic-scale in real-time have blockbuster potential. A team of scientists with the Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC) Berkeley has developed a technique for encapsulating liquids of nanocrystals between layers of graphene so that chemical reactions in the liquids can be imaged with an electron microscope. With this technique, movies can be made that provide unprecedented direct observations of physical, chemical and biological phenomena that take place in liquids on the nanometer scale. (more…)

International Team Uncovers New Genes That Shape Brain Size, Intelligence

By Guest PostApril 16, 2012Scienceadenine, alzheimer's disease, arthur toga, australia, bad gene, barbara franke, bigger brain, bipolar disorder, brain size, brain study, centers, cytosine, dementia, depression, derrek hibar, disorder, DNA, Europe, gene, genetic variant, geneticist, guanine, hmga2, human gene, intelligence, iq test, jason stein, margaret wright, memory, mental illnesses, neda jahanshad, nick martin, North America, paul thompson, project enigma, rita cantor, rudy senstad, schizophrenia, thymine

*UCLA-launched partnership identifies genes that boost or lessen risk of brain atrophy, mental illness, Alzheimer’s disease*

In the world’s largest brain study to date, a team of more than 200 scientists from 100 institutions worldwide collaborated to map the human genes that boost or sabotage the brain’s resistance to a variety of mental illnesses and Alzheimer’s disease.

Published April 15 in the advance online edition of the journal Nature Genetics, the study also uncovers new genes that may explain individual differences in brain size and intelligence. (more…)

UCLA Study Identifies Genes Linked to Post-Traumatic Stress Disorder

By Guest PostApril 7, 2012Healthafghanistan, alan steinberg, american, armen goenjian, danger, david walling, devon schmidt, disorder, DNA, ernest noble, flashbacks, gene, hyper alert, Iraq, julia bailey, natural disaster, post traumatic, ptsd, ptsd symptom, rape, stress disorder, symptoms, tph1, tph2, uma dandekar, variant, war, war veteran

Why do some people experience post-traumatic stress disorder (PTSD) while others who suffered the same ordeal do not? A new UCLA study may shed light on the answer.

UCLA scientists have linked two genes involved in serotonin production to a higher risk of developing PTSD. Published in the April 3 online edition of the Journal of Affective Disorders, the findings suggest that susceptibility to PTSD is inherited, pointing to new ways of screening for and treating the disorder. (more…)

Organics Probably Formed Easily in Early Solar System

By Guest PostApril 4, 2012Scienceamino acids, amphiphiles, bombard, building blocks, cellular membrane, cometary, computer simulation, DNA, dynamics, fred ciesla, life on earth, meteorite, nasa ames, nucleobases, organic compound, planet, proteins, rna, science express, scott sandford, solar nebula, uchicago, ultraviolet radiation, uv radiation

Complex organic compounds, including many important to life on Earth, were readily produced under conditions that likely prevailed in the primordial solar system. Scientists at the University of Chicago and NASA Ames Research Center came to this conclusion after linking computer simulations to laboratory experiments.

Fred Ciesla, assistant professor in geophysical sciences at UChicago, simulated the dynamics of the solar nebula, the cloud of gas and dust from which the sun and the planets formed. Although every dust particle within the nebula behaved differently, they all experienced the conditions needed for organics to form over a simulated million-year period. (more…)

Slow Snails, Fast Genes: Predatory Snails Refine Venoms Through Continuous Gene Duplication

By Guest PostApril 3, 2012Natureamerican samoa, cone snail, conotoxins, dan chang, DNA, gene, gene family, genus conus, hawaii, marine, molecular mechanism, neurotoxin, olfactory genes, panama, scorpion, snake, thomas duda, tropical, venoms

ANN ARBOR, Mich.— When tropical marine cone snails sink their harpoon-like teeth into their prey, they inject paralyzing venoms made from a potent mix of more than 100 different neurotoxins.

Biologists have known for more than a decade that the genes which provide the recipes for cone snail toxins are among the fastest-evolving genes in the animal kingdom, enabling these predatory gastropods to constantly refine their venoms to more precisely target the neuromuscular systems of their prey. (more…)

How Megakaryocytes Get so Big — and The Bad Things That Happen When They Don’t

By Guest PostMarch 2, 2012Scienceblood cells, cell division, diane krause, DNA, ect2, ee chun cheng, elenoe smith, endomitosis, gef h1, gene, giant blood cells, guanine exchange factors, krause lab, leukemia, lin wang, malfunction, malignant leukemias, megakaryoblastic leukemias, megakaryocyte maturation, megakaryocytes, mkl1, mutant, platelets, process, protein, sharon lin, siying zou, stephanie halene, supernova, yuan gao

Yale researchers have discovered how megakaryocytes — giant blood cells that produce wound-healing platelets — manage to grow 10 to 15 times larger than other blood cells.

The findings, to be published March 13 in the journal Developmental Cell, also hint at how a malfunction in this process may cause a form of leukemia. (more…)

To Be A Scientist

By Guest PostFebruary 24, 2012Scienceaids, aids drug, alzheimer, anti aging, anti cancer compounds, anti tumor agents, bob vince, carbovirs, cdd, center for drug design, chemical formulas, childhood home, detection, DNA, eugene mccarthy, explosive, genetic material, hall of fame, hiv, nobel laureate, norman borlaug, patent, precursor, quality of life, scholars walk, scientist, senator, t cells, tc campus, treatment, wall of discovery, walter mondale, ziagen

*How Bob Vince changed the world*

Where does it begin, the act of becoming a scientist? Perhaps with a bowling ball, its finger holes packed with explosives, which when detonated, launch the ball into the air, cracking the otherwise pristine concrete walkway of your childhood home in four places, much to the consternation of your father. Or maybe with an explosion of homemade rocket fuel in your basement chemistry lab that scares your mother half to death. And all this before the troublesome teen years.

Bob Vince can’t be sure where his becoming a scientist began. But where it led changed the world. (more…)

New Molecule Has Potential to Help Treat Genetic Diseases and HIV

By Guest PostFebruary 13, 2012Scienceamy rhoden smith, austin, base molecule, brent iverson, cells, chromosome, DNA, dna sequence, double helix, garen holman, georgetown, hiv, kenneth johnson, legos, maha zewail foote, molecule, naphthalenetetracarboxylic diimide, ndi, protease inhibitors, sequence of genes, southwestern university, spiral staircase, university of texas, viral dna

AUSTIN, Texas — Chemists at The University of Texas at Austin have created a molecule that’s so good at tangling itself inside the double helix of a DNA sequence that it can stay there for up to 16 days before the DNA liberates itself, much longer than any other molecule reported.

It’s an important step along the path to someday creating drugs that can go after rogue DNA directly. Such drugs would be revolutionary in the treatment of genetic diseases, cancer or retroviruses such as HIV, which incorporate viral DNA directly into the body’s DNA. (more…)

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