Human Papillomavirus (HPV) drives a greater number of head and neck cancers than previously thought, finds new research from UCL and the University of Southampton. (more…)
Tag Archives: cancers
Like finally seeing all the gears of a watch and how they work together, researchers from UCLA and UC Berkeley have, for the first time ever, solved the puzzle of how the various components of an entire telomerase enzyme complex fit together and function in a three-dimensional structure.
The creation of the first complete visual map of the telomerase enzyme, which is known to play a significant role in aging and most cancers, represents a breakthrough that could open up a host of new approaches to fighting disease, the researchers said. (more…)
Berkeley Lab Researchers Resolve EGFR Activation Mystery
Researchers with Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC) Berkeley have provided important new details into the activation of the epidermal growth factor receptor (EGFR), a cell surface protein that has been strongly linked to a large number of cancers and is a major target of cancer therapies.
“The more we understand about EGFR and the complex molecular machinery involved in the growth and proliferation of cells, the closer we will be to developing new and more effective ways to cure and treat the many different forms of cancer,” says chemist Jay Groves, one of the leaders of this research. “Through a tour-de-force of quantitative biology techniques that included cutting edge time-resolved fluorescence spectroscopy in living cells, Nuclear Magnetic Resonance, and computational modeling, we’ve determined definitively how EGFR becomes activated through to its epidermal growth factor (EGF) ligand.” (more…)
Decoded genome reveals secrets of pigeon traits and origins
Scientists have decoded the genetic blueprint of the rock pigeon, unlocking secrets about pigeons’ Middle East origins, feral pigeons’ kinship with escaped racing birds and how mutations give pigeons traits like feather head crests.
“Birds are a huge part of life on Earth, but we know surprisingly little about their genetics,” says Michael Shapiro, one of the study’s two principal authors and a biologist at the University of Utah. (more…)
*As we begin the New Year, a look at some of the stories of futuristic scenarios brought to life in 2011, plus developments that promise dramatic improvements in the near future.*
REDMOND, Wash. – Jan. 3, 2012 – From revolutionizing the way we interact with computers to developing tools to speed development of cures for crippling diseases, 2011 was a year of forward-thinking breakthroughs at Microsoft. See some of the innovations introduced in 2011 and how Microsoft is working to take new technologies from the lab to the living room. (more…)
Suppressing a newly identified protein involved in regulating cell division could be a novel strategy for fighting certain cancers because it stops the malignant cells from dividing and causes them to die quickly, according to a study by researchers at UCLA’s Jonsson Comprehensive Cancer Center.
During the five-year study, designed to seek new targets for anti-cancer therapies, researchers discovered that depleting the protein, called STARD9, also helped the commonly used chemotherapy drug Taxol work more effectively against certain cancers. (more…)
*UA scientists have teamed up to study the relationship between arsenic in human toenails and arsenic concentration in drinking water. Exposure to arsenic is associated with several chronic diseases ranging from dermatitis to various cancers.*
Scientists from the University of Arizona specializing in environmental health sciences and pharmacology and toxicology have teamed up with the help of a seed grant to study the relationship between arsenic in human toenails and arsenic concentration in drinking water.
Arsenic exposure in Arizona is a concern because of naturally occurring contamination of groundwater, said Miranda Loh, assistant professor of environmental health sciences at the UA Mel and Enid Zuckerman College of Public Health. (more…)
*Microsoft has partnered with the University of Washington’s Baker Laboratory to help scientists supercharge the computing power of their protein folding research with Windows Azure. Helping scientists get faster results could mean speeding up cures for Alzheimer’s, cancers, salmonella, and malaria.*
REDMOND, Wash. – June 14, 2011 – Cloud computing is helping biologists uncloud one of nature’s biggest mysteries: proteins.
Microsoft has partnered with the University of Washington’s Baker Laboratory, one of the world’s top computational biology labs, to give scientists access to some high-caliber computing power. That, in turn, helps them explore and understand proteins, which could eventually lead to thwarting everything from Alzheimer’s to Malaria, and from cancer to salmonella. (more…)