New research sheds light on role of HPV in head and neck cancers
Human Papillomavirus (HPV) drives a greater number of head and neck cancers than previously thought, finds new research from UCL and the University of Southampton. (more…)
Tag Archives: immune systems
Compound stymies polyomaviruses in lab
There is no approved medicine to treat polyomaviruses, which afflict people with weakened immune systems, but scientists have found that a chemical compound called Retro-2 is able to reduce significantly the infectivity and spread of the viruses in lab cell cultures. Now they are working to improve it.
PROVIDENCE, R.I. [Brown University] — A team of scientists reports that a small-molecule compound showed significant success in controlling the infectivity and spread of three polyomaviruses in human cell cultures. To date there has been no medicine approved to treat such viruses, which prey on transplant recipients, people with HIV, and others whose immune systems have been weakened. (more…)
‘Chemical Compounds in Trees Can Fight Deadly Staph Infections in Humans’
COLUMBIA, Mo. – Most people would never suspect that a “trash tree,” one with little economic value and often removed by farmers due to its ability to destroy farmland, could be the key to fighting a deadly bacterium. Now, a University of Missouri researcher has found an antibiotic in the Eastern Red Cedar tree that is effective against methicillin-resistant Staphylococcus aureus (MRSA), a “superbug” that is resistant to most medications.
“I wanted to find a use for a tree species that is considered a nuisance,” said Chung-Ho Lin, research assistant professor in the MU Center for Agroforestry at the College of Agriculture, Food and Natural Resources. “This discovery could help people fight the bacteria as well as give farmers another cash crop.” (more…)
Heat Therapy Could Be New Treatment for Parasitic Skin Disease
COLUMBUS, Ohio – Scientists are hoping that heat therapy could eventually replace a complex drug regimen as the first-line treatment of a parasitic skin infection common in tropical and subtropical regions of the world.
The researchers successfully treated the skin infection with heat therapy in two patients whose immune systems were deficient, which lowered their bodies’ ability to respond to medication. Both patients have remained free of the parasitic disease, called cutaneous leishmaniasis, for more than a year since receiving the heat treatment.
That long-term effectiveness, especially in people with compromised immune systems, makes this one-time application of heat to skin lesions an appealing alternative to the conventional treatment for the infection — a series of about 20 consecutive daily drug injections that is rife with compliance problems, researchers say. (more…)
Research Suggests HIV Causes Rapid Aging in Key Infection-fighting Cells
In the early years of the AIDS epidemic, being infected with the virus that causes the disease was considered a virtual death sentence. But with the development of antiretroviral therapy, many with HIV are now living much longer. In fact, it is estimated that by 2015, about half of all HIV-positive individuals will be older than 50.
Yet those over 50 also progress to AIDS faster than adults in their 20s or 30s. And those in the younger age bracket — even those responding well to antiretroviral therapy — still exhibit illnesses and clinical conditions commonly associated with older people, such as certain cancers and liver diseases. For the most part, the reasons for this have remained a mystery. (more…)