Tag Archives: alzheimer

Yoga Reduces Stress; Now It’s Known Why

UCLA study helps caregivers of people with dementia

Six months ago, researchers at UCLA published a study that showed using a specific type of yoga to engage in a brief, simple daily meditation reduced the stress levels of people who care for those stricken by Alzheimer’s and dementia. Now they know why.

As previously reported, practicing a certain form of chanting yogic meditation for just 12 minutes daily for eight weeks led to a reduction in the biological mechanisms responsible for an increase in the immune system’s inflammation response. Inflammation, if constantly activated, can contribute to a multitude of chronic health problems. (more…)

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Probability of Success

UD alum and ‘Jeopardy!’ champ Craig tells students it’s important to take chances

When Li Liao, associate professor in the University of Delaware Department of Computer and Information Sciences, saw Roger Craig’s almost-perfect GRE score while Craig was applying to graduate school at UD, the faculty member said to himself, “Wow, this guy is smart.”

Liao says he took a chance on Craig, who had no formal training in computer science. Craig would go on to exceed his adviser’s expectations, studying bioinformatics and earning master’s and doctoral degrees in computer and information sciences at UD.

Craig also would set several records on the Jeopardy! quiz show in 2010 and 2011, among them, the all-time record for single-day winnings ($77,000). Craig said that when he hit the daily doubles, he almost always bet everything. (more…)

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Scientists Pinpoint How Vitamin D May Help Clear Amyloid Plaques Found in Alzheimer’s

A team of academic researchers has identified the intracellular mechanisms regulated by vitamin D3 that may help the body clear the brain of amyloid beta, the main component of plaques associated with Alzheimer’s disease.

Published in the March 6 issue of the Journal of Alzheimer’s Disease, the early findings show that vitamin D3 may activate key genes and cellular signaling networks to help stimulate the immune system to clear the amyloid-beta protein. (more…)

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To Be A Scientist

*How Bob Vince changed the world*

Where does it begin, the act of becoming a scientist? Perhaps with a bowling ball, its finger holes packed with explosives, which when detonated, launch the ball into the air, cracking the otherwise pristine concrete walkway of your childhood home in four places, much to the consternation of your father. Or maybe with an explosion of homemade rocket fuel in your basement chemistry lab that scares your mother half to death. And all this before the troublesome teen years.

Bob Vince can’t be sure where his becoming a scientist began. But where it led changed the world. (more…)

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UCLA Scientists Boost Memory By Stimulating Key Site in Brain

*Mechanism holds potential for improving recall in dementia patients*

Have you ever gone to the movies and forgotten where you parked the car? New UCLA research may one day help you improve your memory.

UCLA neuroscientists have demonstrated that they can strengthen memory in human patients by stimulating a critical junction in the brain. Published in the Feb. 9 edition of the New England Journal of Medicine, the finding could lead to a new method for boosting memory in patients with early Alzheimer’s disease. (more…)

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MSU Researchers Identify Path to Treat Parkinson’s Disease at Its Inception

EAST LANSING, Mich. — Imagine if doctors could spot Parkinson’s disease at its inception and treat the protein that triggers it before the disease can sicken the patient.

A team of researchers led by Basir Ahmad, a postdoctoral researcher at Michigan State University, has demonstrated that slow-wriggling alpha-synuclein proteins are the cause of aggregation, or clumping together, which is the first step of Parkinson’s. The results are published in the current issue of the Proceedings of the National Academy of Sciences. (more…)

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Editor’s Picks: Turning Futuristic Visions into Reality

*As we begin the New Year, a look at some of the stories of futuristic scenarios brought to life in 2011, plus developments that promise dramatic improvements in the near future.*

REDMOND, Wash. – Jan. 3, 2012 – From revolutionizing the way we interact with computers to developing tools to speed development of cures for crippling diseases, 2011 was a year of forward-thinking breakthroughs at Microsoft. See some of the innovations introduced in 2011 and how Microsoft is working to take new technologies from the lab to the living room. (more…)

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Andrew Artenstein: Essential Enzymes Key to Disease, Maybe Treatments

*Proprotein convertases are enzymes that activate many essential proteins, but they are also implicated in many processes that cause disease. In a research review in the New England Journal of Medicine, Andrew Artenstein and Steven Opal argue that proprotein convertases are potentially rich targets for developing therapies.*

Most people have never heard of proprotein convertases, but the enzymes activate many proteins that are essential for life. Unfortunately, their fundamental role puts them in the middle of many processes that cause disease – not just cancer or athlerosclerosis, but both of those and Alzheimer’s and anthrax and the flu and an amazing variety of other maladies.

In a research review article appearing Dec. 29 in the New England Journal of Medicine, Andrew Artenstein, physician-in-chief in the Department of Medicine at Memorial Hospital, and Steven Opal, chief of infectious diseases at Memorial Hospital, argue that proprotein convertases (PCs) are potentially rich targets for developing therapies. Artenstein, who with Opal is on the faculty of the Warren Alpert School of Medicine, explained PCs to David Orenstein. (more…)

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