Tag Archives: alzheimer

Manufacturing Goes Viral

*Researchers coax viruses to assemble into synthetics with microstructures and properties akin to those of corneas, teeth and skin*

Using a simple, single-step process, engineers and scientists at the University of California at Berkeley recently developed a technique to direct benign, filamentous viruses called M13 phages to serve as structural building blocks for materials with a wide range of properties.

By controlling the physical environment alone, the researchers caused the viruses to self-assemble into hierarchically organized thin-film structures, with complexity that ranged from simple ridges, to wavy, chiral strands, to truly sophisticated patterns of overlapping strings of material–results that may also shed light on the self-assembly of biological tissues in nature. (more…)

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Scientists Unfolding Protein Mystery, Fighting Disease with Windows Azure

*Microsoft has partnered with the University of Washington’s Baker Laboratory to help scientists supercharge the computing power of their protein folding research with Windows Azure. Helping scientists get faster results could mean speeding up cures for Alzheimer’s, cancers, salmonella, and malaria.*

REDMOND, Wash. – June 14, 2011 – Cloud computing is helping biologists uncloud one of nature’s biggest mysteries: proteins.

Microsoft has partnered with the University of Washington’s Baker Laboratory, one of the world’s top computational biology labs, to give scientists access to some high-caliber computing power. That, in turn, helps them explore and understand proteins, which could eventually lead to thwarting everything from Alzheimer’s to Malaria, and from cancer to salmonella. (more…)

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Go Figure: Math Model May Help Researchers with Stem Cell, Cancer Therapies

GAINESVILLE, Fla. — The difficult task of sorting and counting prized stem cells and their cancer-causing cousins has long frustrated scientists looking for new ways to help people who have progressive diseases.

But in a development likely to delight math teachers, University of Florida researchers have devised a series of mathematical steps that accomplishes what the most powerful microscopes, high-throughput screening systems and protein assays have failed to do — assess how rapidly stem cells and their malignant, stemlike alter egos increase their numbers. (more…)

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Research Indicates Green Tea Protects Against Alzheimer’s and Cancer

A study by Newcastle University in Britain, indicates that green tea may protect the brain from diseases such as Alzheimer’s and other types of dementia. The research, published in the journal Phytomedicine, also suggests that the ancient Chinese remedy that has been popularized throughout the world may also have an important role in protecting the body against cancer.

In the study, scientists investigated whether the beneficial properties of green tea, which had already been proven in newly prepared and undigested tea, were still active once the tea was digested. (more…)

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Yale Scientists Find Molecular Glue Needed To Wire the Brain

Yale University researchers have found that a single molecule not only connects brain cells but also changes how we learn. The findings, reported in the December 9 issue of the journal Neuron, may help researchers discover ways to improve memory and could lead to new therapies to correct neurological disorders.

The junctions between brain cells over which nerve pulses pass — called synapses — are crucial for regulating learning and memory and how we think. Aberrations in the structure and function of synapses have been linked to mental retardation and autism, while synapses are lost in the aging brains of Alzheimer’s patients. (more…)

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Does Sex Matter? It May When Evaluating Mental Status

Adrianna Mendrek. Image credit : University of Montreal

Schizophrenia is a mental disorder that differs between the sexes in terms of age at onset, symptomatology, response to medication, and structural brain abnormalities. Now, a new study from the Université de Montréal shows that there is gender difference between men and women’s mental ability – with women performing better than men. These findings, published recently in, Schizophrenia Research, have implications for the more than 300 000 affected Canadians. 

“We are the first to report sex differences in brain function of schizophrenics,” says Université de Montréal professor, Adrianna Mendrek a researcher at the Centre de Recherche Fernand-Seguin, Hospital Louis-H Lafontaine. “We chose to study a task involving mental rotation of a three dimensional image because in healthy men and women, this consistently elicits differences in terms of reaction time and performance accuracy.”  (more…)

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Obesity: Yale Researcher Explains Why It’s All in Our Heads

Tamas Horvath. Image credit: Yale University

Tamas Horvath is the first to tell you that he doesn’t study obesity. But his research on the effects of metabolism on higher brain functions could provide deeper understanding of the brain’s link to appetite, weight and to metabolic disorders such as diabetes and obesity.

His lab was the first to provide evidence that the brain uses fat as fuel. Horvath has also studied how endocrine signals in the brain regulate neurodegenerative diseases such as Parkinson’s and Alzheimer’s.

Horvath followed his father and grandfather into veterinary medicine in his native Hungary, but his training sparked a passion for basic research. His achievements have earned him a long title that speaks to his varied research interests. He became chair of the Department of Comparative Medicine at Yale School of Medicine in 2005, and he is also a professor in the Departments of Obstetrics, Gynecology & Reproductive Sciences and Neurobiology. Horvath also heads the Program on Integrative Cell Signaling and the Neurobiology of Metabolism. (more…)

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Nicotine May Play Key Role in Promising Alzheimer’s Therapy

COLLEGE PARK, Md. — A team of neuroscientists has discovered important new information in the search for an effective treatment for Alzheimer’s disease, the debilitating neurological disorder that afflicts more than 5.3 million Americans and is the sixth-leading cause of death in the United States. Hey-Kyoung Lee , associate professor in the University of Maryland Department of Biology, and her research team have shown that they may be able to eliminate debilitating side effects caused by a promising Alzheimer’s drug by stimulating the brain’s nicotine receptors. (more…)

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