Tag Archives: dementia

Off-label use of antipsychotics higher in nursing homes with lower registered nurse staffing, MU study finds

COLUMBIA, Mo. – At least 5.7 million people in the U.S. have a form of dementia such as Alzheimer’s, including more than half of all nursing home residents. Previous research has shown that nursing homes often overmedicate dementia patients with antipsychotic medications despite the fact that the FDA has not approved these medications for the treatment of dementia. Now, new research from the University of Missouri has found that increased staffing of registered nurses in Missouri nursing homes is associated with lower use of antipsychotics. (more…)

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Link between vitamin D and dementia risk confirmed

Vitamin D deficiency is associated with a substantially increased risk of dementia and Alzheimer’s disease in older people, according to the most robust study of its kind ever conducted.

An international team, led by Dr David Llewellyn at the University of Exeter Medical School, found that study participants who were severely Vitamin D deficient were more than twice as likely to develop dementia and Alzheimer’s disease.

The team studied elderly Americans who took part in the Cardiovascular Health Study. They discovered that adults in the study who were moderately deficient in vitamin D had a 53 per cent increased risk of developing dementia of any kind, and the risk increased to 125 per cent in those who were severely deficient. (more…)

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UA Grows Gourmet Mushrooms That Recycle Waste

UA plant scientists are growing gourmet mushrooms on coffee grounds, landscape waste, even pizza boxes – and reducing that waste to compost.

The University of Arizona class is called “Mushrooms, Molds and Man.” Intrigued, undergraduate Lauren Jackson decided to learn about “Kingdom Fungi” and its impact on the world.

He was hooked in a heartbeat. Barely into the course, “I just raised my hand and asked about research opportunities.” That week he started working in the lab with UA mycologist Barry Pryor. (more…)

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Do peppers reduce risk of Parkinson’s?

Eating peppers — which are in the same botanical family as tobacco — may reduce the risk of Parkinson’s disease. The findings are reported in the May 9 edition of the Annals of Neurology, a journal of the American Neurological Association and Child Neurology Society.

Nearly one million people in the United States are living with Parkinson’s disease, a neurodegenerative disorder that results from the loss of dopamine-producing brain cells. In early stages, Parkinson’s is characterized by difficulties in controlling movement. Initial symptoms include hand tremors, limb rigidity, and problems walking. As the disease progresses, cognitive problems may develop and advance into dementia. (more…)

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Human Cognition Depends Upon Slow-Firing Neurons

Good mental health and clear thinking depend upon our ability to store and manipulate thoughts on a sort of “mental sketch pad.” In a new study, Yale School of Medicine researchers describe the molecular basis of this ability — the hallmark of human cognition — and describe how a breakdown of the system contributes to diseases such as schizophrenia and Alzheimer’s disease.

“Insults to these highly evolved cortical circuits impair the ability to create and maintain our mental representations of the world, which is the basis of higher cognition,” said Amy Arnsten, professor of neurobiology and senior author of the paper published in the Feb. 20 issue of the journal Neuron. (more…)

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UCLA Study First to Image Concussion-Related Abnormal Brain Proteins in Retired NFL Players

Technique may lead to earlier diagnosis, tracking of brain disorders in athletes

Sports-related concussions and mild traumatic brain injuries have grabbed headlines in recent months, as the long-term damage they can cause becomes increasingly evident among both current and former athletes. The Centers for Disease Control and Prevention estimates that millions of these injuries occur each year.

Despite the devastating consequences of traumatic brain injury and the large number of athletes playing contact sports who are at risk, no method has been developed for early detection or tracking of the brain pathology associated with these injuries. (more…)

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Yoga Reduces Stress; Now It’s Known Why

UCLA study helps caregivers of people with dementia

Six months ago, researchers at UCLA published a study that showed using a specific type of yoga to engage in a brief, simple daily meditation reduced the stress levels of people who care for those stricken by Alzheimer’s and dementia. Now they know why.

As previously reported, practicing a certain form of chanting yogic meditation for just 12 minutes daily for eight weeks led to a reduction in the biological mechanisms responsible for an increase in the immune system’s inflammation response. Inflammation, if constantly activated, can contribute to a multitude of chronic health problems. (more…)

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International Team Uncovers New Genes That Shape Brain Size, Intelligence

*UCLA-launched partnership identifies genes that boost or lessen risk of brain atrophy, mental illness, Alzheimer’s disease*

In the world’s largest brain study to date, a team of more than 200 scientists from 100 institutions worldwide collaborated to map the human genes that boost or sabotage the brain’s resistance to a variety of mental illnesses and Alzheimer’s disease.

Published April 15 in the advance online edition of the journal Nature Genetics, the study also uncovers new genes that may explain individual differences in brain size and intelligence. (more…)

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