Category Archives: Science

Lack of Protein Sp2 Disrupts Neuron Creation in Brain

By Guest PostJanuary 21, 2013Sciencecancer research, cell cycle regulator, cerebral cortex, creation of neurons, experimental mice, function of sp2, genetic tools, guanxi xiao, haifeng yin, how protein works, huixuan liang, jon horowitz, mechanism, neural therapies, neurodevelopmental diseases, north Carolina, offspring, program stem cell, protein, regeneration, regenerative medicine, simon hippenmeyer, skin, sp2, state university, stem cells, troy ghashghaei, tumor

A protein known as Sp2 is key to the proper creation of neurons from stem cells, according to researchers at North Carolina State University. Understanding how this protein works could enable scientists to “program” stem cells for regeneration, which has implications for neural therapies.

Troy Ghashghaei and Jon Horowitz, both faculty in NC State’s Department of Molecular Biomedical Sciences and researchers in the Center for Comparative Medicine and Translational Research, wanted to know more about the function of Sp2, a cell cycle regulator that helps control how cells divide. Previous research from Horowitz had shown that too much Sp2 in skin-producing stem cells resulted in tumors in experimental mice. Excessive amounts of Sp2 prevented the stem cells from creating normal cell “offspring,” or skin cells. Instead, the stem cells just kept producing more stem cells, which led to tumor formation. (more…)

Portable X-Ray Source Invented at MU Could Put Medical Diagnosis and Terrorism Prevention in the Palm of the Hand

By Guest PostJanuary 19, 2013Sciencecell phone, compact source, crystal, curiosity rover, electric charge, electricity, energy, forms of radiation, hand held scanners, interplanetary probes, lithium niobate, phenomenon, piezoelectric effect, portable x ray, power consumption, radiation source, radioactive material, radioisotopes, remote, scanner, scott kovaleski, shooting the rays, star trek, stress, tricorders, university of missouri, x-rays

The inexpensive device could improve health in the developing world and reduce mining risks

COLUMBIA, Mo. — The hand-held scanners, or tricorders, of the Star Trek movies and television series are one step closer to reality now that a University of Missouri engineering team has invented a compact source of X-rays and other forms of radiation. The radiation source, which is the size of a stick of gum, could be used to create inexpensive and portable X-ray scanners for use by doctors, as well as to fight terrorism and aid exploration on this planet and others.

“Currently, X-ray machines are huge and require tremendous amounts of electricity,” said Scott Kovaleski, associate professor of electrical and computer engineering at MU. “In approximately three years, we could have a prototype hand-held X-ray scanner using our invention. The cell-phone-sized device could improve medical services in remote and impoverished regions and reduce health care expenses everywhere.” (more…)

Searching for the Lost Royal City of Nubia in Northern Sudan

By Guest PostJanuary 18, 2013Culture, Scienceel kurru, kings of nubia, kush, lost royal city, northern sudan, nubia, nubian capital, nubian pyramid

ANN ARBOR — Geoff Emberling is doing what few archaeologists do anymore in a world that has been worked over pretty well by picks, trowels and shovels. He’s searching for a lost royal city. (more…)

Born to Lead? Leadership Can be an Inherited Trait, Study Finds

By Guest PostJanuary 18, 2013Politics, Scienceassessment, Barack Obama, born to lead, child, de neve, democratic primary, dna sequence, economic, framingham heart study, garfld986, gene, genetic difference, genetic discrimination, genetic trait, genotype, harvard, hillary clinton, inherited trait, jan emmanuel, leadership, leadership behaviour, leadership position, leadership skills, learning environment, new hampshire, nyu, political outcomes, professor john antonakis, rs4950, selection, tendency, ucl, unite for change, united states, university college london, university of california, variation, workplace

Genetic differences are significantly associated with the likelihood that people take on managerial responsibilities, according to new research from UCL (University College London).

The study, published online in Leadership Quarterly, is the first to identify a specific DNA sequence associated with the tendency for individuals to occupy a leadership position. Using a large twin sample, the international research team, which included academics from Harvard, NYU, and the University of California, estimate that a quarter of the observed variation in leadership behaviour between individuals can be explained by genes passed down from their parents. (more…)

Nanopore Sequencing: DNA Prefers to Dive Head First into Nanopores

By Guest PostJanuary 18, 2013Sciencebertrand duplantier, de gennes, derek stein, dna molecules, gelatin molecules, genetic code, mirna mihovilovic, molecule entropy, molecule zipping, molecules of dna, nanopore sequencing, nanopores, nick hagerty, nucleotide base, pierre gilles, polymer network, sensor, solid state nanopores, theory of jello

In the 1960s, Nobel laureate Pierre-Gilles de Gennes postulated that someday researchers could test his theories of polymer networks by observing single molecules. Researchers at Brown observed single molecules of DNA being drawn through nanopores by electrical current and figured out why they most often travel head first.

PROVIDENCE, R.I. [Brown University] — If you want to understand a novel, it helps to start from the beginning rather than trying to pick up the plot from somewhere in the middle. The same goes for analyzing a strand of DNA. The best way to make sense of it is to look at it head to tail.

Luckily, according to a new study by physicists at Brown University, DNA molecules have a convenient tendency to cooperate. (more…)

Better Way to Understand Plasmid Cloning from AddGene

By Guest PostJanuary 17, 2013Scienceaddgene, ailments, backbone vector, biologically engineered, chromosomes, circular fragments, cloning process, cloning vital organs, digestion, dna strands, double stranded dna, first successful cloning, gel purification, gene, manipulating genes, medical research, molecular cloning, molecular level, molecule cloning, molly the sheep, non profit repository, original chromosomal dna, pcr, plasmid cloning, plasmid land, plasmids, prolong human life, red, red cloning, repository, restriction enzyme digest, restructure diseases, scottish lambs, sub cloning, vector

Medical research has been studying molecular cloning for centuries. While many remember the Scottish lambs as the first successful cloning, there have been countless medical advances since then. Many of them are not as evident or dramatic as Molly the sheep, they have been blazing the trail for cloning vital organs, DNA strands and chromosomes in hopes of curtailing or even curing the maladies that plague the human race. Plasmids are at the forefront of this research in hopes they can learn how to insert DNA strands and restructure diseases or ailments on a molecular level.

It is difficult to describe what Plasmid is exactly. Plasmid is a biologically engineered DNA strands that are meant to be used in existing organisms as well as creating new ones. There are many aspects of it used in different ways from molecule cloning, manipulating genes or advancing medical research. Plasmids are circular fragments of double-stranded DNA. Plasmids are used in DNA strands and they can be replicated independently of original chromosomal DNA that created them. While they are mainly used for studying purposes at the moment in biological laboratories, they are meant to advance medical research and hopefully be used to prolong human life. (more…)

4,000-year-old Shaman’s Stones Discovered near Boquete, Panama

By Guest PostJanuary 17, 2013Sciencedorasque people, ritual practices, shaman knowledge, shaman stones, shamanistic practice

Archaeologists working at the Smithsonian Tropical Research Institute in Panama have discovered a cluster of 12 unusual stones in the back of a small, prehistoric rock-shelter near the town of Boquete. The cache represents the earliest material evidence of shamanistic practice in lower Central America.

Ruth Dickau, Leverhulme Post-doctoral Fellow at the University of Exeter, unearthed the cache of stones in the Casita de Piedra rock-shelter in 2007. A piece of charcoal found directly underneath the cache was radiocarbon dated to 4,800 years ago. A second fragment of charcoal in a level above the cache was dated to 4,000 years ago. (more…)

NASA Mars Rover Preparing to Drill into First Martian Rock

By Guest PostJanuary 16, 2013Scienceaileen yingst, bassinite, bradbury landing, calcium, california institute, camera, chemcam, chemical composition, concretions, curiosity, drill hardware, drilling, drilling target, drt, dust removal tool, Environment, evidence, flat rock, fractures, france, gale crater, gillespie lake rock, gypsum, hydrated calcium sulfate, hydrogen, imager, internet buzz, jet propulsion laboratory, john grotzinger, john klein, laser pulsing chemistry, level, mahli, mars, mars hand lens, mars rover curiosity, mars science laboratory, martian flower, martian material, mast camera, mastcam, microbial life, mineral, mission, nantes, NASA, nicolas mangold, pale veins, pasadena, red planet, richard cook, rock, samples, sedimentary rocks, shaler unit, shallow depression, sheepbed outcrop, stream flow, sulfur, Technology, terrain, tucson, veins, wet environment, wet history, yellowknife bay

PASADENA, Calif. — NASA’s Mars rover Curiosity is driving toward a flat rock with pale veins that may hold clues to a wet history on the Red Planet. If the rock meets rover engineers’ approval when Curiosity rolls up to it in coming days, it will become the first to be drilled for a sample during the Mars Science Laboratory mission.

The size of a car, Curiosity is inside Mars’ Gale Crater investigating whether the planet ever offered an environment favorable for microbial life. Curiosity landed in the crater five months ago to begin its two-year prime mission. (more…)