A protein associated with neuron damage in Alzheimer’s patients provides a superior scaffold for growing central nervous system cells in the lab. The findings could have clinical implications for producing neural implants and offers new insights on the complex link between the apoE4 apolipoprotein and Alzheimer’s disease. Results appear in the journal Biomaterials. (more…)
Berkeley Lab scientists join an international collaboration to understand how archaea and bacteria work together deep in a cold sulfur spring
In the fall of 2010, Hoi-Ying Holman of the U.S. Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) was approached by an international team researching a mysterious microbial community discovered deep in cold sulfur springs in southern Germany.
“They told me what they were doing and said, ‘We know what you contributed to the oil-spill research,’” recalls Holman, who heads the Chemical Ecology group in Berkeley Lab’s Earth Sciences Division. “They wondered if I could help them determine the biochemistry of their microbe samples.” (more…)
Using a brain-imaging technique that examines the entire infant brain, researchers have found that the anatomy of certain brain areas – the hippocampus and cerebellum – can predict children’s language abilities at 1 year of age. (more…)
By using tiny liquid lenses that self-assemble around microscopic objects, a team from UCLA’s Henry Samueli School of Engineering and Applied Science has created an optical microscopy method that allows users to directly see objects more than 1,000 times smaller than the width of a human hair.
Coupled with computer-based computational reconstruction techniques, this portable and cost-effective platform, which has a wide field of view, can detect individual viruses and nanoparticles, making it potentially useful in the diagnosis of diseases in point-of-care settings or areas where medical resources are limited. (more…)
Engineers report research milestones in fuel cells, flexible composites
Faculty and students in the University of Delaware’s College of Engineering continue to blaze a trail of innovation, reporting recent research milestones in flexible composites and fuel cells. (more…)
In awarding Yale’s George Daniel Mostow its 2013 Wolf Foundation Prize in mathematics — one of the field’s premier global awards — the foundation offered this crisp assessment: “Few mathematicians,” it said, “can compete with the breadth, depth, and originality of his works.” (more…)
Researchers at North Carolina State University have come up with a technique to embed needle-like carbon nanofibers in an elastic membrane, creating a flexible “bed of nails” on the nanoscale that opens the door to development of new drug-delivery systems.
The research community is interested in finding new ways to deliver precise doses of drugs to specific targets, such as regions of the brain. One idea is to create balloons embedded with nanoscale spikes that are coated with the relevant drug. Theoretically, the deflated balloon could be inserted into the target area and then inflated, allowing the spikes on the balloon’s surface to pierce the surrounding cell walls and deliver the drug. The balloon could then be deflated and withdrawn. (more…)
PASADENA, Calif. — Researchers using NASA’s Mars Reconnaissance Orbiter see seasonal changes on far-northern Martian sand dunes caused by warming of a winter blanket of frozen carbon dioxide.
Earth has no naturally frozen carbon dioxide, though pieces of manufactured carbon-dioxide ice, called “dry ice,” sublime directly from solid to gas on Earth, just as the vast blankets of dry ice do on Mars. A driving factor in the springtime changes where seasonal coverings of dry ice form on Mars is that thawing occurs at the underside of the ice sheet, where it is in contact with dark ground being warmed by early-spring sunshine through translucent ice. The trapped gas builds up pressure and breaks out in various ways. (more…)
