EAST LANSING, Mich. — What makes people great? Popular theorists such as the New Yorker’s Malcolm Gladwell and the New York Times’ David Brooks argue that intelligence plays a role – but only up to a point. Beyond that, they say, it’s practice, practice, practice. (more…)
Cell-penetrating peptides, such as the HIV TAT peptide, are able to enter cells using a number of mechanisms, from direct entry to endocytosis, a process by which cells internalize molecules by engulfing them.
Further, these cell-penetrating peptides, or CPPs, can facilitate the cellular transfer of various molecular cargoes, from small chemical molecules to nano-sized particles and large fragments of DNA. Because of this ability, CPPs hold great potential as in vitro and in vivo delivery vehicles for use in research and for the targeted delivery of therapeutics to individual cells. (more…)
Small bypass vessels which act as a ‘back-up system’ for the heart’s main arteries play a significant role in reducing the mortality of patients with coronary artery disease, according to new research. (more…)
*Berkeley Lab Researchers Resolve Sub-nanometer Structure of Cascade, an Ally for Human Immune System*
A complex of proteins in the bacterium E.coli that plays a critical role in defending the microbe from viruses and other invaders has been discovered to have the shape of a seahorse by researchers with the U.S Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab). This discovery holds far more implications for your own health than you might think.
In its never-ending battle to protect you from infections by bacteria, viruses, toxins and other invasive elements, your immune system has an important ally – many allies in fact. By the time you reach adulthood, some 90-percent of the cells in your body are microbial. These microbes – collectively known as the microbiome – play a critical role in preserving the health of their human host. (more…)
Researchers at UCLA’s Jonsson Comprehensive Cancer Center have developed a way to image the spread of a dangerous form of prostate cancer earlier than today’s conventional imaging techniques. The new method may allow oncologists to find and treat metastases more quickly and give patients a better chance at survival.
The gene-based imaging system targets castration-resistant prostate cancer, an aggressive form of the disease that has become resistant to the hormone treatment known as androgen-deprivation therapy. Once this treatment no longer works, the cancer will progress within 12 to 18 months, and the prognosis becomes grim, said senior study author Dr. Lily Wu, a professor of molecular and medical pharmacology and a Jonsson Cancer Center researcher. (more…)
*Discovery could lead to treatments for muscular dystrophy and ALS*
COLUMBIA, Mo. – Researchers at the University of Missouri have identified a communication breakdown between nerves and muscles in mice that may provide new insight into the debilitating and fatal human disease known as spinal muscular atrophy (SMA).
“Critical communication occurs at the point where nerves and muscles ‘talk’ to each other. When this communication between nerves and muscles is disrupted, muscles do not work properly,” said Michael Garcia, associate professor of biological sciences in the College of Arts and Science and the Christopher S. Bond Life Sciences Center. “In this study, we found that delivery of ‘the words’ a nerve uses to communicate with muscles was disrupted before they arrived at the nerve ending.” (more…)
EAST LANSING, Mich. — People may be learning while sleeping – an unconscious form of memory that is still not well understood, according to a study by Michigan State University researchers.
The findings are highlighted in the Journal of Experimental Psychology: General. (more…)
EAST LANSING, Mich. — Continuing a global effort to prevent malaria infections, Michigan State University researchers have created a new malaria vaccine – one that combines the use of a disabled cold virus with an immune system-stimulating gene – that appears to increase the immune response against the parasite that causes the deadly disease.
At the same time, the group led by Andrea Amalfitano of the College of Osteopathic Medicine also discovered another immune-system stimulating agent – created at MSU and which has been successful in improving immune responses in vaccines for diseases such as HIV – paradoxically made for a less effective malaria vaccine. (more…)
