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Yale Researchers Find Genetic Link Between Heart Disease and Brain Aneurysms

By Guest PostNovember 25, 2011Health, ScienceAli Ozturk, aneurysms, atherosclerosis, blood vessels, brain, bursting blood vessels, cardiovascular disorders, constriction of blood vessels, DNA, elasticity, endothelin receptor, genes, genetic risk factors, heart disease, hypertension, intracranial aneurysms, Katsuhito Yasuno, Kaya Bilguvar, mehmet bakircioglu, murat gunel, Richard Lifton, Shrikant Mane, variant of gene, vasospasm, vessel spasm, vessel tone

Yale School of Medicine researchers have discovered that a variant of a gene linked to heart disease also increases the risk of deadly aneurysms of blood vessels in the brain. The discovery of this link raises hopes for new treatments for intracranial aneurysms, which affect more than a half million people worldwide annually.

“Existing drugs already target this common pathway and, in the future, could help treat or prevent aneurysms in people who are at risk,” said Murat Gunel, professor of neurosurgery, genetics and neurobiology and senior author of the study, published the week of Nov. 21 in the Proceedings of the National Academy of Sciences. (more…)

How the Brain Strings Words Into Sentences

By Guest PostNovember 23, 2011Healthbrain imaging, language disorders, language impairments, language processing, nerve fibers, neural pathways

Distinct neural pathways are important for different aspects of language processing, researchers have discovered, studying patients with language impairments caused by neurodegenerative diseases. (more…)

Yale Researchers Discover Promising Anti-HIV Agents

By Guest PostNovember 23, 2011Health, Sciencebristol myers squibb, chemical compounds, d4t, DNA, effective hiv treatments, festinavir, function of an enzyme, genetic material, hiv 1 reverse transcriptase, hiv and human t cells, hiv drugs, hiv replication, human t cells, infection of human cells, jlj494, karen s anderson, less toxic aids drugs, mariela bollini, non nucleoside reverse transcriptase inhibitors, prevent hiv, prophylactic anti hiv treatment, reverse transcriptase inhibitor, tai shun lin, toxicity, vinay v thakur, wild type, wild type hiv, william h prusoff, william l jorgensen, yung chi tommy cheng, zerit

Researchers at Yale University have discovered new chemical compounds that prevent HIV from replicating in human T-cells. These compounds could result in new, highly effective HIV treatments that are 10 to 2000 times more potent than HIV drugs now on the market.

“The current compounds or slight variants could become drugs,” said Professor William L. Jorgensen, one of two principal investigators behind the research. The other is Karen S. Anderson, a pharmacology professor at Yale School of Medicine. They reported their results online Nov. 15 in the Journal of Medicinal Chemistry. (more…)

Treatment for Juvenile Offenders Shows Positive Effects 22 Years Later, Including Reduced Recidivism Rates

By Guest PostNovember 20, 2011Healthbehavior change, juvenile offenders, multisystemic therapy

COLUMBIA, Mo. – More than 20 years ago, Charles Borduin, a University of Missouri researcher, developed a treatment for juvenile offenders that has become one of the most widely used evidence-based treatments in the world. Now, he has found that the treatment continues to have positive effects on former participants more than 20 years after treatment. (more…)

At a Loss for Words

By Guest PostNovember 20, 2011Health, Scienceaphasia, aphasia research project, biological and cognitive processes, brain, brain damage, brain impairs, bullet, celeste barajas, communication impairments, gabrielle giffords, human communication problems, inability to speak or write, language and hearing sciences, language impairment, language recovery, loss of phonology, magnetic resonance imaging, mechanisms of recovery, mri, national institutes of health, network of brain regions, neuroimaging, pelagie beeson, pima county, rehabilitation, scanner, speech, speech language pathology, steven rapcsak, stroke, traumatic brain injury, university of arizona

*Research into aphasia – the inability to speak or write well-formulated sentences and words – is strong at the UA. Researchers have received $2 million toward the study of the condition.*

The National Institutes of Health have awarded the University of Arizona’s Aphasia Research Project in the department of speech, language and hearing sciences a $2 million grant to research communication impairments in adults who have suffered brain injury.

Aphasia – the inability to speak or write well-formulated sentences and words – is a common result of a stroke or a traumatic brain injury such as the one suffered by Rep. Gabrielle Giffords, who was shot in the head earlier this year. The bullet damaged regions of the brain that are critical for language and control of the right side of the body. (more…)

New Mouthwash Targeting Harmful Bacteria May Render Tooth Decay A Thing of The Past

By Guest PostNovember 19, 2011Healthamericans, anti dental caries drug, antimicrobial technology, bacteria, broad spectrum antibiotics, c16g2, c3 jian inc, cavities, colgate palmolive, dental caries, experimental mouthwash, fluoride, human body, infectious diseases, microbiologist, mouthwash, no hee park, normal ecological balance, optimum health, parasitic infections, pathogenic organisms, s mutans bacteria, small scale study, smart bomb, streptococcus mutans, thomas mitchell, tooth decay, ucla, united states, wenyuan shi, yeast

A new mouthwash developed by a microbiologist at the UCLA School of Dentistry is highly successful in targeting the harmful Streptococcus mutans bacteria that is the principal cause tooth decay and cavities.

In a recent clinical study, 12 subjects who rinsed just one time with the experimental mouthwash experienced a nearly complete elimination of the S. mutans bacteria over the entire four-day testing period. The findings from the small-scale study are published in the current edition of the international dental journal Caries Research. (more…)

UA Physician: Diet and Lifestyle Key to Preventing Diabetes

By Guest PostNovember 18, 2011Healthamericans, big benefits, breast cancer and aids, carbohydrate intake, craig stump, diabetes, dietary and physical activity, endocrine specialist, high caloric foods, highly processed carbohydrates, ice cream, obesity, pre diabetic, simple behavior changes, stamina, type 2 diabetes, university of arizona college of medicine tucson, weight loss, white bread, white noodles, white potatoes, white rice

*Dr. Craig Stump, interim director of the Diabetes Research Program at the UA College of Medicine–Tucson, suggests simple behavior changes that can add up to big benefits.*

Diabetes kills more people each year than breast cancer and AIDS combined, and 79 million Americans are at high risk for developing type 2 diabetes, according to the U.S. Centers for Disease Control and Prevention and the American Diabetes Association. (more…)

More fiber, but not necessarily less fat, good for teen diets

By Guest PostNovember 14, 2011Healtha diet high in fiber, diabetes in teenagers, fat or cholesterol, fiber-rich, good for teens diets, high-fiber, joseph carlson, lower risk of heart disease, metabolic syndrome decreases, michigan state university, national health and nutrition examination survey, nutrient-dense, plant-based foods, reduce metabolic syndrome, sports and cardiovascular nutrition

EAST LANSING, Mich. — A diet high in fiber – but not necessarily one low in saturated fat or cholesterol – is tied to a lower risk of heart disease and type-2 diabetes in teenagers, according to new findings from Michigan State University.

A study led by Joseph Carlson of MSU’s Division of Sports and Cardiovascular Nutrition suggests to reduce metabolic syndrome – a collection of risk factors including high blood pressure and a large waistline – it is more important to emphasize diets including fiber-rich, nutrient-dense, plant-based foods than focus on restricting foods high in cholesterol or saturated fat. (more…)

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