Tag Archives: human body

Bisphenol A Affects Sex-Specific Reproductive Behaviors in a Monogamous Animal Species, Says MU Researcher

By Guest PostFebruary 13, 2013Environment, Health, Scienceaggression, american public, anxiety, assess, beer, behavioral effects, behaviors of males, bisphenol a, boys versus girls, bpa, california mouse, canned goods, chemical exposure, cheryl rosenfeld, david geary, denise warzak, eldin jasarevic, female hormones, females, gregory vandas, human body, human societies, mark ellersieck, monogamous rodent, nutritional support, offspring, paper receipts, peromyscus californicus, plastic containers, post natal exposure, pre, r michael roberts, reproductive associated behaviors, researchers, risk to children, rodents, rosenfelds lab, scott williams, sex specific, soda cans, species, university of missouri

Animal Findings Suggest That Gender May Also Influence Chemical Exposure Risks for Humans

COLUMBIA, Mo. — Parents, teachers and psychologists know boys and girls behave differently. However, that difference isn’t taken into account by most methods used to assess the risk to children from chemical exposure, according to Cheryl Rosenfeld, associate professor of biomedical sciences in the University of Missouri’s Bond Life Sciences Center. A series of experiments by Rosenfeld studied the effects of prenatal exposure to bisphenol A (BPA) on later reproductive-associated behaviors using a socially and genetically monogamous rodent, the California mouse, which may better mirror most human societies than other rodents. (more…)

Study: Alternate Walking and Running to Save Energy, Maintain Endurance

By Guest PostFebruary 4, 2013Healthalternate walking, best strategy, bus stop, calculation, conserve energy, data, exoskeletons, goal, human body, human energy costs, hypothesis, leroy long, less energy, maintain endurance, manoj srinivasan, marathon finish line, natural environment, notion, ohio state university, optimize energy, pam frost gorder, physical factor, prosthetic devices, running, save energy, transition region, treadmill

COLUMBUS, Ohio — Forget “slow and steady wins the race.” A new study shows that, at least sometimes, the best way to conserve energy and reach your destination on time is to alternate between walking and running—whether your goal is the bus stop or a marathon finish line.

In the January 30, 2013 issue of the Journal of the Royal Society Interface, researchers examined how people budget their time as they travel on foot to reach a destination at a particular appointed time. The study found that when people have neither too much time nor too little time to reach their destination, they naturally switch back and forth between walking and running, which turns out to be the best strategy for saving energy. (more…)

Chemists Unlock Potential Target For Drug Development

By Guest PostJanuary 22, 2012Scienceadditives, analytical methods, bleeding, blood flow, blood platelets, bloodstream, clotting, cystic fibrosis, dana spence, diabetes, diseases, drug testing, druggable receptors, enzymes, human body, hypertension, michigan state university, molecule, nf449, p2x1, p2y receptor, pharmaceutical target, platelets, receptor, red blood cells, sickle cell anemia

EAST LANSING, Mich. — A receptor found on blood platelets whose importance as a potential pharmaceutical target has long been questioned may in fact be fruitful in drug testing, according to new research from Michigan State University chemists.

A team led by Dana Spence of MSU’s Department of Chemistry has revealed a way to isolate and test the receptor known as P2X1. By creating a new, simple method to study it after blood is drawn, the team has unlocked a potential new drug target for many diseases that impact red blood cells, such as diabetes, hypertension and cystic fibrosis. (more…)

Gut Microbe Networks Differ From Norm in Obese People, Systems Biology Approach Reveals

By Guest PostJanuary 13, 2012Scienceabundance of enzymes, alfred p sloan foundation, biomarkers, body weight, building blocks of proteins, cohesive system, disease resistance, elhanan borenstein, energy, gene set, gut, habitats, human anatomy, human body, human genes, human gut, human host, human microbiome, immunity and nutrition, in silico modeling, inflammatory bowel disease, integrated biological system, microbes, microorganism, modeled network, modularity, multiple microbial species, organism, periphery, peter j turnbaugh, sharon greenblum, species, supra organism, university of washington, vitamins

For the first time, researchers have analyzed the multitude of microorganisms residing in the human gut as a complex, integrated biological system, rather than a set of separate species. Their approach has revealed patterns that correspond with excess body weight.

The senior author of the paper, Elhanan Borenstein, assistant professor of genome sciences at the University of Washington, said, “Our research introduces a novel framework, applying systems biology and in-silico (computer) modeling to study the human microbiome – the complex ensemble of microorganisms that populate the human body – as a single cohesive system.” (more…)

New Mouthwash Targeting Harmful Bacteria May Render Tooth Decay A Thing of The Past

By Guest PostNovember 19, 2011Healthamericans, anti dental caries drug, antimicrobial technology, bacteria, broad spectrum antibiotics, c16g2, c3 jian inc, cavities, colgate palmolive, dental caries, experimental mouthwash, fluoride, human body, infectious diseases, microbiologist, mouthwash, no hee park, normal ecological balance, optimum health, parasitic infections, pathogenic organisms, s mutans bacteria, small scale study, smart bomb, streptococcus mutans, thomas mitchell, tooth decay, ucla, united states, wenyuan shi, yeast

A new mouthwash developed by a microbiologist at the UCLA School of Dentistry is highly successful in targeting the harmful Streptococcus mutans bacteria that is the principal cause tooth decay and cavities.

In a recent clinical study, 12 subjects who rinsed just one time with the experimental mouthwash experienced a nearly complete elimination of the S. mutans bacteria over the entire four-day testing period. The findings from the small-scale study are published in the current edition of the international dental journal Caries Research. (more…)

Geoscientists Find Key to Why Some Patients Get Infections from Cardiac Implants

By Guest PostOctober 26, 2011Health, Scienceamericans, antibiotics, atomic force microscopy, bacteria adhere to mineral surfaces, bacterial and human proteins, bacterial cells, biofilm, biofilm formation, biofilm of persistent bacteria, blood infection bacteremia, charles darwin, common human blood protein, contaminated device, deadly blood infection, defibrillators, duke university medical center, enriqueta barrera, eric taylor, fibronectin, fibronectin binding protein a, gene mutations, genetic variants, geobiologists, heart implants, human body, implanted cardiac devices, infections, l barth reller, molecular dynamics simulations, nadia casillas ituarte, national science foundation, ohio state university, pacemakers, patients with implants, prosthetic cardiac valves, proteins of infectious bacteria, ruchirej yongsunthon, single nucleotide polymorphisms, snips, snps, solid substrate, staph bacteria, staphylococcus aureus, steven lower, supaporn lamlertthon, united states, vance fowler

*Bacterial cells have gene mutations that allow them to ‘stick’ to the devices*

New research suggests that some patients develop a potentially deadly blood infection from their implanted cardiac devices because bacterial cells in their bodies have gene mutations that allow them to stick to the devices.

Geoscientists were the major contributors to the finding.

Proceedings of the National Academy of Sciences published the study results online this week. (more…)

Berkeley Lab Scientists Find That Normal Breast Cells Help Kill Cancer Cells

By Guest PostApril 20, 20111 commentHealth, Scienceberkeley lab, breast cancer cells, cytostatic, cytotoxic, dna mutations, extracellular matrix culture, healthy cells, human body, il25, immune system, inflammation, interleukin 25, malignant phenotype, mammary epithelial cells, microenvironmental factors, mina bissell, natural defense mechanism against cancer, pathogens, protein, saori furuta, treatment of breast cancer, tumor cells, tumor surveillance system

It is well known that the human body has a highly developed immune system to detect and destroy invading pathogens and tumor cells. Now, researchers at the U.S. Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) have shown that the body has a second line of defense against cancer – healthy cells. A new study shows that normal mammary epithelial cells, as they are developing, secrete interleukin 25, a protein known for its role in the immune system’s response to inflammation, for the express purpose of killing nearby breast cancer cells.

“We found that normal breast cells provide an innate defense mechanism against cancer by producing interleukin 25 (IL25) to actively and specifically kill breast cancer cells,” says breast cancer authority Mina Bissell, of Berkeley Lab’s Life Sciences Division, who led this research. “This suggests that IL25 receptor signaling may provide a new therapeutic target for the treatment of breast cancer.” (more…)

Replacing Body Parts Now More Than ‘Science Fiction’

By Guest PostFebruary 19, 2011Sciencecells, clinical trials, clotting, engineered lungs, genetically different cells, human body, human veins, infection, laura niklason, lunatic fringe, natural lungs, obstruction, regenerative medicine, science fiction, time of my life, tissue engineered lungs, tissue engineered replacement, vascular surgeons, vascular system

If Dr. Laura Niklason has her way, vascular surgeons will someday be able to pull human veins off a shelf, whenever they want, to save lives.

Niklason is a pioneer in the science — and art — of tissue-engineered replacement of human body components. Last year, she led a research team that successfully implanted tissue-engineered lungs, cultured in vitro, in adult rats. For short intervals of time, the engineered lungs exchanged oxygen and carbon dioxide similarly to natural lungs. (more…)