Scientists from Berkeley Lab and the Max Planck Institute for Terrestrial Microbiology analyze a unique microbial motor
The protein structure of the motor that propels archaea has been characterized for the first time by a team of scientists from the U.S. Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) and Germany’s Max Planck Institute (MPI) for Terrestrial Microbiology.
The motility structure of this third domain of life has long been called a flagellum, a whip-like filament that, like the well-studied bacterial flagellum, rotates like a propeller. But although the archaeal structure has a similar function, it is so profoundly different in structure, genetics, and evolution that the researchers argue it deserves its own name: archaellum. (more…)
About the video: watch an animation showing the changes in the structure of a T7 virus as it infects an E. coli bacterium.
AUSTIN, Texas — The detailed changes in the structure of a virus as it infects an E. coli bacterium have been observed for the first time, report researchers from The University of Texas at Austin and The University of Texas Health Science Center at Houston (UT Health) Medical School this week in Science Express. (more…)
EAST LANSING, Mich. — A team of researchers at Michigan State University has documented the step-by-step process in which organisms evolve new functions.
The results, published in the current issue of Nature, are revealed through an in-depth, genomics-based analysis that decodes how E. coli bacteria figured out how to supplement a traditional diet of glucose with an extra course of citrate. (more…)
Professor and students study how microbial life changes along the river
The mercury is pushing 100, but professor Michael Sadowsky and two assistants leave the indoor coolness for the bank of the Mississippi River as it flows by the University of Minnesota Twin Cities campus.
The three men send a bucket splashing into the current and haul back a water sample. That doesn’t affect the river much, but information locked away in bacteria from the sample may tell them a great deal about how the river’s microbial communities change along its course through Minnesota and how human activity affects them.(more…)
*JBEI Researchers Develop a New Candidate for a Cleaner, Greener and Renewable Diesel Fuel*
A class of chemical compounds best known today for fragrance and flavor may one day provide the clean, green and renewable fuel with which truck and auto drivers fill their tanks. Researchers at the U.S. Department of Energy’s Joint BioEnergy Institute (JBEI) have engineered Escherichia coli (E. coli) bacteria to generate significant quantities of methyl ketone compounds from glucose. In subsequent tests, these methyl ketones yielded high cetane numbers – a diesel fuel rating comparable to the octane number for gasoline – making them strong candidates for the production of advanced biofuels.
“Our findings add to the list of naturally occurring chemical compounds that could serve as biofuels, which means more flexibility and options for the biofuels industry,” says Harry Beller, a JBEI microbiologist who led this study. “We’re especially encouraged by our finding that it is possible to increase the methyl ketone titer production of E. coli more than 4,000-fold with a relatively small number of genetic modifications.” (more…)
COLUMBUS, Ohio – Water-associated infectious disease outbreaks are more likely to occur in areas where a region’s population density is growing, according to a new global analysis of economic and environmental conditions that influence the risk for these outbreaks.
Ohio State University scientists constructed a massive database containing information about 1,428 water-associated disease outbreaks that were reported between 1991 and 2008 around the world. By combining outbreak records with data on a variety of socio-environmental factors known about the affected regions, the researchers developed a model that can be used to predict risks for water-associated disease outbreaks anywhere in the world. (more…)
EAST LANSING, Mich. — Antibiotics in pig feed increased the number of antibiotic resistant genes in gastrointestinal microbes in pigs, according to a study conducted by Michigan State University and the U.S. Department of Agriculture’s Agricultural Research Service.
Published in the current edition of the Proceedings of the National Academy of Sciences, the comprehensive study focused on understanding the effects of conventional, in-feed antibiotics in U.S. farms. (more…)
*Joint BioEnergy Institute Researchers Develop CAD-Type Tools for Engineering RNA Control Systems*
The computer assisted design (CAD) tools that made it possible to fabricate integrated circuits with millions of transistors may soon be coming to the biological sciences. Researchers at the U.S. Department of Energy (DOE)’s Joint BioEnergy Institute (JBEI) have developed CAD-type models and simulations for RNA molecules that make it possible to engineer biological components or “RNA devices” for controlling genetic expression in microbes. This holds enormous potential for microbial-based sustainable production of advanced biofuels, biodegradable plastics, therapeutic drugs and a host of other goods now derived from petrochemicals. (more…)
