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Measuring the Distant Universe in 3-D

By Guest PostMay 7, 2011Science3 d map, absorption, anže slosar, apache point observatory, bao, baryon acoustic oscillation, baryon oscillation, baryon oscillation spectroscopic survey, berkeley lab, bill carithers, BOSS, centers of galaxies, dark energy, david schlegel, james rich, lyman alpha forest, map intergalactic hydrogen gas, new mexico, of light years, precision tool, quasars, red galaxies, redshift, sdss, sloan digital sky survey, sloan telescope, spectrum, supermassive black holes, universe, wiggly structure

*Berkeley Lab-led BOSS proves it can do the job with quasars*

The biggest 3-D map of the distant universe ever made, using light from 14,000 quasars — supermassive black holes at the centers of galaxies many billions of light years away — has been constructed by scientists with the third Sloan Digital Sky Survey (SDSS-III).

The map is the first major result from the Baryon Oscillation Spectroscopic Survey (BOSS), SDSS-III’s largest survey, whose principal investigator is David Schlegel of the U.S. Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab). The huge new map was presented at the April meeting of the American Physical Society in Anaheim, CA, by Anže Slosar of Brookhaven National Laboratory. (more…)

Anti-Helium Discovered in the Heart of STAR

By Guest PostApril 26, 2011Scienceaccelerator technology, alpha magnetic spectrometer, ams, anti heavy hydrogen, anti hypertriton, antialpha, antideuteron, antielectron, antihelium 4, antinucleons, antiparticles, antiproton, baryon, baryon number, berkeley lab, carl anderson, CERN, collisions of energetic gold nuclei, ernest rutherford, experiment, hans georg ritter, heaviest antiparticle, nu xu, nucleus, nucleus of antihelium 4, nucleus of antihydrogen, particle, positron, relativistic heavy ion collider, rhic, star, star experiment

*Berkeley Lab nuclear scientists join with their international colleagues in the latest record-breaking discovery at RHIC*

Eighteen examples of the heaviest antiparticle ever found, the nucleus of antihelium-4, have been made in the STAR experiment at RHIC, the Relativistic Heavy Ion Collider at the U.S. Department of Energy’s Brookhaven National Laboratory.

“The STAR experiment is uniquely capable of finding antihelium‑4,” says the STAR experiment’s spokesperson, Nu Xu, of the Nuclear Science Division (NSD) at Lawrence Berkeley National Laboratory (Berkeley Lab). “STAR already holds the record for massive antiparticles, last year having identified the anti-hypertriton, which contains three constituent antiparticles. With four antinucleons, antihelium-4 is produced at a rate a thousand times lower yet. To identify the 18 examples required sifting through the debris of a billion gold-gold collisions.” (more…)

Berkeley Lab Scientists Find That Normal Breast Cells Help Kill Cancer Cells

By Guest PostApril 20, 20111 commentHealth, Scienceberkeley lab, breast cancer cells, cytostatic, cytotoxic, dna mutations, extracellular matrix culture, healthy cells, human body, il25, immune system, inflammation, interleukin 25, malignant phenotype, mammary epithelial cells, microenvironmental factors, mina bissell, natural defense mechanism against cancer, pathogens, protein, saori furuta, treatment of breast cancer, tumor cells, tumor surveillance system

It is well known that the human body has a highly developed immune system to detect and destroy invading pathogens and tumor cells. Now, researchers at the U.S. Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) have shown that the body has a second line of defense against cancer – healthy cells. A new study shows that normal mammary epithelial cells, as they are developing, secrete interleukin 25, a protein known for its role in the immune system’s response to inflammation, for the express purpose of killing nearby breast cancer cells.

“We found that normal breast cells provide an innate defense mechanism against cancer by producing interleukin 25 (IL25) to actively and specifically kill breast cancer cells,” says breast cancer authority Mina Bissell, of Berkeley Lab’s Life Sciences Division, who led this research. “This suggests that IL25 receptor signaling may provide a new therapeutic target for the treatment of breast cancer.” (more…)

Berkeley Scientists at AAAS Highlight Challenges of Meeting State Energy Goals by 2050

By Guest PostMarch 2, 2011Environmentberkeley lab, biodiversity, biofuel crops, biofuels, biomass, california, carbon capture and sequestration, carbon sequestration technology, carbon storage, ebi, energy analyst, energy biosciences institute, greenhouse gas emissions, james mcmahon, jeffery greenblatt, load balancing triangle, low carbon, portraits of the california energy system in 2050, saline aquifers

California is showing the way for the rest of the nation in terms of reducing greenhouse gas emissions, having set an ambitious goal to reduce these emissions to 80 percent below 1990 levels by the year 2050. Given that energy demand is projected to double by 2050, experts agree that the state will have to dramatically overhaul its energy systems to achieve its greenhouse gas emission goals.

At the 2011 Annual Meeting of the American Association for the Advancement of Science, some of the specific challenges and issue ahead were discussed in a session titled “Portraits of the California Energy System in 2050: Cutting Emissions by 80 Percent.” Contributing to this discussion were two scientists from Berkeley Lab and one from the Energy Biosciences Institute (EBI), in which Berkeley Lab is a partner. (more…)

A Second Pathway for Antidepressants: Berkeley Lab Reports New Fluorescent Assay Reveals TREK1 Mechanism

By Guest PostFebruary 25, 2011Scienceantidepressant drugs, berkeley lab, c terminal, cell based fluorescent assay, cytoplasm, ehud isacoff, flow of electrical current, fluorescent protein, fluoxetine, gfp, green fluorescent protein, guillaume sandoz, high speed transistors, human brain, ion channels, membrane, molecular gates, neurons, pharmacological agents, plasma membrane, protein, prozac, sarah bell, transmembrane proteins, trek1, trek1 potassium channel

Using a unique and relatively simple cell-based fluorescent assay they developed, scientists with the U.S. Department of Energy (DOE)’s Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC), Berkeley have identified a means by which fluoxetine, the active ingredient in Prozac, suppresses the activity of the TREK1 potassium channel. TREK1 activity has been implicated in mood regulation and could be an important target for fluoxetine and other antidepressant drugs. (more…)

Scientists identify key enzyme in microbial immune system

By Guest PostSeptember 10, 20102 commentsSciencearchaea, bacteria, berkeley lab, Bill and Melinda Gates foundation, clustered regularly interspaced short palindromic repea, crispr, crrna molecule, csy4 enzyme, DNA, doudna group, genetic element, jennifer doudna, microbes, movie, nucleic acid, nucleic acid-based immune system, plasmids, rachel haurwitz, terminator

Imagine a war in which you are vastly outnumbered by an enemy that is utterly relentless – attacking you is all it does. The intro to another Terminator movie? No, just another day for microbes such as bacteria and archaea, which face a never-ending onslaught from viruses and invading strands of nucleic acid known as plasmids.

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Study Shows Deepwater Oil Plume in Gulf Degraded by Microbes

By Guest PostAugust 26, 2010Environmentberkeley lab, biodegradation, bp, carbon, deep-sea psychrophilic, deepwater horizon drilling, degradation, gamma-proteobacteria, gulf of mexico, hoi-ying Holman, hydrocarbon-degrading enzymes, microbial ecologist, oil dispersant corexit 9500, oil plume, oxygen depletion, petroleum, petroleum-degrading microbes, terry hazen

In the aftermath of the explosion of BP’s Deepwater Horizon drilling rig in the Gulf of Mexico, a dispersed oil plume was formed at a depth between 3,600 and 4,000 feet and extending some 10 miles out from the wellhead. An intensive study by scientists with the Lawrence Berkeley National Laboratory (Berkeley Lab) found that microbial activity, spearheaded by a new and unclassified species, degrades oil much faster than anticipated. This degradation appears to take place without a significant level of oxygen depletion.

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Berkeley Study Shows Ozone and Nicotine a Bad Combination for Asthma

By Guest PostAugust 17, 2010Health, Scienceasthma, asthma hazard, berkeley lab, chen-lin liu, Health, hugo destaillats, indoor environments, jared smith, kevin wilson, lara gundel, mohamad sleiman, musahid ahmed, ozone, roy kaltschmidt, secondhand tobacco, smoke, thirdhand smoke, tobacco-related disease, ultraviolet light, vuv light

Another reason for including asthma on the list of potential health risks posed by secondhand tobacco smoke, especially for non-smokers, has been uncovered. Furthermore, the practice of using ozone to remove the smell of tobacco smoke from indoor environments, including hotel rooms and the interiors of vehicles, is probably a bad idea.

(more…)

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