Tag Archives: berkeley lab

Sharpening The Nanofocus: Berkeley Lab Researchers Use Nanoantenna to Enhance Plasmonic Sensing

Such highly coveted technical capabilities as the observation of single catalytic processes in nanoreactors, or the optical detection of low concentrations of biochemical agents and gases are an important step closer to fruition. Researchers with the U.S. Department of Energy (DOE)’s Lawrence Berkeley National Laboratory (Berkeley Lab), in collaboration with researchers at the University of Stuttgart in Germany, report the first experimental demonstration of antenna-enhanced gas sensing at the single particle level. By placing a palladium nanoparticle on the focusing tip of a gold nanoantenna, they were able to clearly detect changes in the palladium’s optical properties upon exposure to hydrogen. (more…)

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It Takes a Community of Soil Microbes to Protect Plants From Disease

*Berkeley Lab scientists decipher immune system for plants beneath our feet*

Those vegetables you had for dinner may have once been protected by an immune system akin to the one that helps you fight disease. Scientists from the U.S. Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) and the Netherland’s Wageningen University found that plants rely on a complex community of soil microbes to defend themselves against pathogens, much the way mammals harbor a raft of microbes to avoid infections.

The scientists deciphered, for the first time, the group of microbes that enables a patch of soil to suppress a plant-killing pathogen. Previous research on the phenomenon of disease-suppressive soil had identified one or two pathogen-fighting microbes at work. (more…)

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Measuring the Distant Universe in 3-D

*Berkeley Lab-led BOSS proves it can do the job with quasars*

The biggest 3-D map of the distant universe ever made, using light from 14,000 quasars — supermassive black holes at the centers of galaxies many billions of light years away — has been constructed by scientists with the third Sloan Digital Sky Survey (SDSS-III).

The map is the first major result from the Baryon Oscillation Spectroscopic Survey (BOSS), SDSS-III’s largest survey, whose principal investigator is David Schlegel of the U.S. Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab). The huge new map was presented at the April meeting of the American Physical Society in Anaheim, CA, by Anže Slosar of Brookhaven National Laboratory. (more…)

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Anti-Helium Discovered in the Heart of STAR

*Berkeley Lab nuclear scientists join with their international colleagues in the latest record-breaking discovery at RHIC*

Eighteen examples of the heaviest antiparticle ever found, the nucleus of antihelium-4, have been made in the STAR experiment at RHIC, the Relativistic Heavy Ion Collider at the U.S. Department of Energy’s Brookhaven National Laboratory.

“The STAR experiment is uniquely capable of finding antihelium‑4,” says the STAR experiment’s spokesperson, Nu Xu, of the Nuclear Science Division (NSD) at Lawrence Berkeley National Laboratory (Berkeley Lab). “STAR already holds the record for massive antiparticles, last year having identified the anti-hypertriton, which contains three constituent antiparticles. With four antinucleons, antihelium-4 is produced at a rate a thousand times lower yet. To identify the 18 examples required sifting through the debris of a billion gold-gold collisions.” (more…)

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Berkeley Lab Scientists Find That Normal Breast Cells Help Kill Cancer Cells

It is well known that the human body has a highly developed immune system to detect and destroy invading pathogens and tumor cells. Now, researchers at the U.S. Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) have shown that the body has a second line of defense against cancer – healthy cells. A new study shows that normal mammary epithelial cells, as they are developing, secrete interleukin 25, a protein known for its role in the immune system’s response to inflammation, for the express purpose of killing nearby breast cancer cells.

“We found that normal breast cells provide an innate defense mechanism against cancer by producing interleukin 25 (IL25) to actively and specifically kill breast cancer cells,” says breast cancer authority Mina Bissell, of Berkeley Lab’s Life Sciences Division, who led this research. “This suggests that IL25 receptor signaling may provide a new therapeutic target for the treatment of breast cancer.” (more…)

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Berkeley Scientists at AAAS Highlight Challenges of Meeting State Energy Goals by 2050

California is showing the way for the rest of the nation in terms of reducing greenhouse gas emissions, having set an ambitious goal to reduce these emissions to 80 percent below 1990 levels by the year 2050. Given that energy demand is projected to double by 2050, experts agree that the state will have to dramatically overhaul its energy systems to achieve its greenhouse gas emission goals.

At the 2011 Annual Meeting of the American Association for the Advancement of Science, some of the specific challenges and issue ahead were discussed in a session titled “Portraits of the California Energy System in 2050: Cutting Emissions by 80 Percent.” Contributing to this discussion were two scientists from Berkeley Lab and one from the Energy Biosciences Institute (EBI), in which Berkeley Lab is a partner. (more…)

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A Second Pathway for Antidepressants: Berkeley Lab Reports New Fluorescent Assay Reveals TREK1 Mechanism

Using a unique and relatively simple cell-based fluorescent assay they developed, scientists with the U.S. Department of Energy (DOE)’s Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC), Berkeley have identified a means by which fluoxetine, the active ingredient in Prozac, suppresses the activity of the TREK1 potassium channel. TREK1 activity has been implicated in mood regulation and could be an important target for fluoxetine and other antidepressant drugs. (more…)

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The Promise of Ion Beam Cancer Therapy

For certain kinds of cancer, the most effective therapy does not use x-rays or gamma rays but beams of ions, the electrically charged cores of atoms, including hydrogen ions (protons) and heavier ions such as carbon and neon.

About the image: Beams of heavy ions can target hard-to-reach tumors with great accuracy and with minimal damage to surrounding tissues. Heidelberg Ion-Beam Therapy Center. Image credit: Berkeley Lab (more…)

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