Digesting lignin, a highly stable polymer that accounts for up to a third of biomass, is a limiting step to producing a variety of biofuels. Researchers at Brown have figured out the microscopic chemical switch that allows Streptomyces bacteria to get to work, breaking lignin down into its constituent parts.(more…)
Knowing the temperatures that viruses, bacteria, worms and all other parasites need to grow and survive could help determine the future range of infectious diseases under climate change, according to new research.
Princeton University researchers developed a model that can identify the prospects for nearly any disease-causing parasite as the Earth grows warmer, even if little is known about the organism. Their method calculates how the projected temperature change for an area would alter the creature’s metabolism and life cycle, the researchers report in the journal Ecology Letters. (more…)
The increasing production and use of antibiotics, about half of which is used in animal production, is mirrored by the growing number of antibiotic resistance genes, or ARGs, effectively reducing antibiotics’ ability to fend off diseases – in animals and humans.
A study in the current issue of the Proceedings of the National Academy of Sciences shows that China – the world’s largest producer and consumer of antibiotics – and many other countries don’t monitor the powerful medicine’s usage or impact on the environment. (more…)
New research shows fungi living beneath the seafloor are widespread
Fungi living beneath the seafloor are widespread in ocean environments around the world, according to a new paper by scientists at the University of Delaware and Woods Hole Oceanographic Institution.
Berkeley Lab scientists join an international collaboration to understand how archaea and bacteria work together deep in a cold sulfur spring
In the fall of 2010, Hoi-Ying Holman of the U.S. Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) was approached by an international team researching a mysterious microbial community discovered deep in cold sulfur springs in southern Germany.
“They told me what they were doing and said, ‘We know what you contributed to the oil-spill research,’” recalls Holman, who heads the Chemical Ecology group in Berkeley Lab’s Earth Sciences Division. “They wondered if I could help them determine the biochemistry of their microbe samples.” (more…)
AMHERST, Mass. – Molecular chaperones have emerged as exciting new potential drug targets, because scientists want to learn how to stop cancer cells, for example, from using chaperones to enable their uncontrolled growth. Now a team of biochemists at the University of Massachusetts Amherst led by Lila Gierasch have deciphered key steps in the mechanism of the Hsp70 molecular machine by “trapping” this chaperone in action, providing a dynamic snapshot of its mechanism.
She and colleagues describe this work in the current issue of Cell. Gierasch’s research on Hsp70 chaperones is supported by a long-running grant to her lab from NIH’s National Institute for General Medical Sciences. (more…)
Some arid lands in the American West degraded by military exercises that date back to General George Patton’s Word War II maneuvers in the Mojave Desert should get a boost from an innovative research project led by the University of Colorado Boulder.
Headed up by CU-Boulder Assistant Professor Nichole Barger, the research team is focused on developing methods to restore biological soil crusts — microbial communities primarily concentrated on soil surfaces critical to decreasing erosion and increasing water retention and soil fertility. Such biological soil crusts, known as “biocrusts,” can cover up to 70 percent of the ground in some arid ecosystems and are dominated by cyanobacteria, lichens, mosses, fungi and bacteria, she said. (more…)