Scientists have discovered a rare genetic mutation that increases the risk of Alzheimer’s disease.
The international team, led by researchers at the UCL Institute of Neurology, studied data from more than 25,000 people and found a link between a rare variant of the TREM2 gene – which is known to play a role in the immune system – and a higher risk of Alzheimer’s.
The paper, which is published in the New England Journal of Medicine, has major implications for our understanding of the causes of Alzheimer’s and the authors believe it is potentially the most influential gene discovery for the disease in the last two decades. (more…)
Health practitioners should use behavior-change tactics so patients take medications as prescribed
COLUMBIA, Mo. – Nearly half of patients taking medications for chronic conditions do not strictly follow their prescribed medication regimens. Failure to use medications as directed increases patients’ risk for side effects, hospitalizations, reduced quality of life and shortened lifespans. Now, a University of Missouri gerontological nursing expert says patients’ poor adherence to prescribed medication regimens is connected to their beliefs about the necessity of prescriptions and concerns about long-term effects and dependency.
MU Assistant Professor Todd Ruppar found that patients’ beliefs about the causes of high blood pressure and the effectiveness of treatment alternatives significantly affected their likelihood of faithfully following prescribed medication regimens. In his pilot study, Ruppar focused on older patients’ adherence to medication treatments that control high blood pressure, a condition that affects nearly 70 million adults in the U.S. and can lead to heart disease and stroke. (more…)
For women of mixed racial or ethnic backgrounds, a new method for measuring bone health may improve the odds of correctly diagnosing their risk of osteoporosis and bone fractures, according to a UCLA-led study.
Currently, assessing osteoporosis and the risk of fractures from small accidents like falls requires a bone density scan. But because these scans don’t provide other relevant fracture-related information, such as bone size and the amount of force a bone is subjected to during a fall, each patient’s bone density is examined against a national database of people with the same age and race or ethnicity. (more…)
Berkeley Lab research could lead to new ways to ID women who have higher risk of breast cancer from low-dose radiation
Scientists from the U.S. Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) have identified tissue mechanisms that may influence a woman’s susceptibility or resistance to breast cancer after exposure to low-dose ionizing radiation, such as the levels used in full-body CT scans and radiotherapy.
The research could lead to new ways to identify women who have higher or lower risks of breast cancer from low-dose radiation. Such a predictive tool could help guide the treatment of cancer patients who may be better served by non-radiation therapies. (more…)
Playing football (soccer) could be the best way for people with high blood pressure, known as hypertension, to improve their fitness, normalise their blood pressure and reduce their risk of stroke, according to research published today (Monday 15 October 2012) in the journal Medicine and Science in Sports and Exercise.
Research from Universities of Exeter and Copenhagen, and Gentofte University Hospital in Denmark suggests football training prevents cardiovascular disease in middle-aged men with hypertension and is more effective than healthy lifestyle advice currently prescribed by GPs.
After six months of football training, three out of four men in this study had blood pressure within the normal, healthy range. (more…)
Blanket bogs, which provide vital habitats for a unique range of plants, birds, small mammals, reptiles and amphibians, are at risk of declining as a result of climate change.
Research by the Universities of Exeter and Bristol in the UK and Macquarie University in Australia, published in the journal Nature Climate Change, shows for the first time how rising temperatures will threaten these sensitive ecosystems.
The study highlights the urgency of developing a plan to protect these important habitats.
Found in wet, coastal areas of high latitude regions, blanket bogs cover around 700,000 hectares of land in the UK, much of it designated as a Site of Special Scientific Interest (SSSI). Blanket bogs are found in the north and west of the UK, extending from Devon in the south to Shetland in the north, and it has been estimated that 10 to15 per cent of the world’s blanket bog occurs in Britain. As well as being crucial in supporting wildlife, blanket bogs also capture and store large amounts of carbon, helping to mitigate against climate change, and reduce the risk of flooding, by slowing down water flow. With some blanket peat being over 9,000 years old, they also hold historically-significant archaeological material. (more…)
A UA study has found poverty, water scarcity, food insecurity and interdependence between the United States and Mexico along the border.
The U.S.-Mexico border is the border in the world with the greatest disparity in access to food and water needed for human survival, according to a report commissioned and published by the Southwest Center at the University of Arizona.
An endowment from the Kellogg Foundation and a UA Confluencenter for Creative Inquiry grant supported the study and its focus on assessing transborder food systems to understand water scarcity and food insecurity within the borderlands region.
The report underscores how in the globalized economy, Arizona and the rest of the United States rely on the skilled labor, water, fresh produce, fish, shellfish and livestock originating in northern Mexico; while in Mexico, the population is increasingly dependent upon frozen and processed foods originating in the United States. (more…)
ANN ARBOR, Mich.— Rising sea levels, melting glaciers, more intense rainstorms and more frequent heat waves are among the planetary woes that may come to mind when climate change is mentioned. Now, two University of Michigan researchers say an increased risk of avian influenza transmission in wild birds can be added to the list.
Population ecologists Pejman Rohani and Victoria Brown used a mathematical model to explore the consequences of altered interactions between an important species of migratory shorebird and horseshoe crabs at Delaware Bay as a result of climate change. (more…)
