Tag Archives: brown university

Economics of Public Health: Study Finds Price for Reducing HIV Risk

By Guest PostFebruary 7, 2013General, Healthbeneficial behaviors, bill, brown university, cash transfer program, cesar infante, condoms, education in mexico, gay men, hiv infection, hiv prevention education, hiv risk behaviors, hiv testing, hiv therapy, increase safe sex, insp, malawi, male sex workers, melinda gates foundation, Mexico City, omar galarraga, policymakers, prediction, reduce infection, sandra sosa rubi, sexually transmitted infections, stefano m bertozzi, sti testing, Tanzania, western nations

With a goal to reduce HIV risk behaviors, researchers investigated whether gay men and male sex workers in Mexico City would participate in a conditional cash transfer program that encourages HIV prevention education and regular testing. A new study in the European Journal of Health Economics reports the price that would get more than 75-percent participation: $288 a year.

PROVIDENCE, R.I. [Brown University] — Studies have found that conditional cash transfer programs, in which governments pay citizens if they consistently practice societally beneficial behaviors, have improved pediatric health care and education in Mexico, increased HIV testing in Malawi, and reduced sexually transmitted infections in Tanzania. Public health researchers therefore investigated whether the idea could be applied to HIV risk behaviors among gay men and male sex workers in Mexico City. A new study reports not only that some members of those populations would change behavior for conditional cash payments, but the exact prices they would accept. (more…)

Aging Cells Lose Their Grip on DNA Rogues

By Guest PostFebruary 3, 2013Scienceabigail peterson, aging bodies, aging cells, balls of protein, barbara mcclintock, brown university, chromatin, chromosomes, computational biologist, desirable genes, DNA, edward peckham, eliza hamm, enzyme, essential genes, euchromatin formations, faire, genetic material, genome, genomic havoc, heterochromatin, heterochromatin prison system, high stakes warfare, hiv drugs, human fibroblast cells, human retrotransposons, jayameenakshi manivannan, jill kreiling, john sedivy, l1, marco de cecco, mobile strands, molecular parasites, nicola neretti, nobel prize, nucleosomes, parasitic strands, reverse transcriptases, rna, sara hillenmeyer, senescent, senescent cells, steven criscione, technique, transposable elements, transposons, transposons in maize, useful genes

Transposable elements are mobile strands of DNA that insert themselves into chromosomes with mostly harmful consequences. Cells try to keep them locked down, but in a new study, Brown University researchers report that aging cells lose their ability to maintain this control. The result may be a further decline in the health of senescent cells and of the aging bodies they compose.

PROVIDENCE, R.I. [Brown University] — Even in our DNA there is no refuge from rogues that prey on the elderly. Parasitic strands of genetic material called transposable elements — transposons — lurk in our chromosomes, poised to wreak genomic havoc. Cells have evolved ways to defend themselves, but in a new study, Brown University researchers describe how cells lose this ability as they age, possibly resulting in a decline in their function and health. (more…)

Ridges on Mars Suggest Ancient Flowing Water

By Guest PostFebruary 2, 2013Scienceactive hydrology, ancient martian subsurface, applied physics lab, biosphere, brown university, craters on mars, curiosity rover, flowing water, fluid flow, fossils of cracks, fracture conduits, gale crater, habitable environment, hydrothermal fluid, hypothesis, jack mustard, johns hopkins university, landing site, lee saper, mars reconnaissance orbiter, martian surface, mineral hardened material, minerals, NASA, nili fossae, nilosyrtis, orientation data, planetary exploration, regional scale volcanism, ridges, subsurface hydrology, surrounding rocks

Ridges in impact craters on Mars appear to be fossils of cracks in the Martian surface, formed by minerals deposited by flowing water. Water flowing beneath the surface suggests life may once have been possible on Mars.

PROVIDENCE, R.I. [Brown University] — Networks of narrow ridges found in impact craters on Mars appear to be the fossilized remnants of underground cracks through which water once flowed, according to a new analysis by researchers from Brown University.

The study, in press in the journal Geophysical Research Letters, bolsters the idea that the subsurface environment on Mars once had an active hydrology and could be a good place to search for evidence of past life. The research was conducted by Lee Saper, a recent Brown graduate, with Jack Mustard, professor of geological sciences. (more…)

Magma in Earth’s Mantle Forms Deeper Than Once Thought

By Guest PostJanuary 10, 2013Environmentananya mallik, anthony withers, brown university, carbon dioxide, carbonated rock, convection, crust, deeper magma, density, earth, earthquake, express lane, geologist, greg hirth, high pressure, jennifer wade, kyusei tsuno, magma, mantle, marc hirschmann, national science foundation, non carbonated rock, ocean floor, peridotite, rajdeep dasgupta, rice university, rock, seafloor, seismic wave, silicate rich mantle, temperature, university of minnesota, volcanic eruption, within the earth

Study simulating pressures in mantle beneath the ocean floor shows that rocks can melt at depths up to 250 kilometers

Magma forms far deeper than geologists previously thought, according to new research results.

A team led by geologist Rajdeep Dasgupta of Rice University put very small samples of peridotite, rock derived from Earth’s mantle, under high pressures in a laboratory.

The scientists found that the rock can and does liquify, at least in small amounts, at pressures equivalent to those found as deep as 250 kilometers down in the mantle beneath the ocean floor. (more…)

Transfusions add Risk in Some Heart Attacks

By Guest PostDecember 27, 2012Healthaabb, abhishek sharma, analyzed data, anemia, blood transfusions, brown university, concentration, debabrata mukherjee, emergency, heart attack, hematocrit, high quality data, jorn wetterslev, liberal transfusions, maimonides medical center, medical factors, meta analysis, new york, patient, randomized trial, red blood cell, risk of death, saurav chatterjee, spectrum, statistical adjustments, texas tech university, treatment, united states, units of blood

A new study published in the Archives of Internal Medicine finds that while blood transfusions for heart attack patients with anemia are commonly performed in emergency rooms, the practice can increase the risk of death when the transfusions are too extensive. The authors, led by Saurav Chatterjee, a cardiology fellow at Brown University, compared evidence from 10 prior studies of more than 203,000 patients.

PROVIDENCE, R.I. [Brown University] — When heart attack patients present in the emergency department with some degree of anemia, or anemic patients have a heart attack, physicians have a tendency, but not much guidance, about whether to provide a blood transfusion. The idea is that a transfusion could help more oxygen get to the heart. Recent national guidelines suggested that there simply isn’t good evidence to encourage or discourage the common practice, but a new meta-analysis of 10 studies involving more than 203,000 such patients comes down on the side of it increasing the risk of death. (more…)

Environmental Cost of Agriculture: Soil Determines Fate of Phosphorous

By Guest PostDecember 17, 2012Environment21st century, agricultural nutrient, agriculture, alfisol, algae, algal blooms, amazon basin, Argentina, brazil, brown university, buenos aires, clean water act, environmental challenge, environmental consequence, environmental cost, farmer, fertilizer, goldilocks problem, grosso, industrial agriculture, iowa farmers, mato, modern farming, mollisol, overfertilization, oxisol, phosphorous, polluted waterways, renewable, shelby riskin, single crop, soil demand, soil ph, soil type, soybean, soybean fields, soybean harvest, stephen porder, ultisol, united states

Brazil’s soybean yields have become competitive with those of the United States and Argentina, but the soil demands a lot of phosphorous, which is not renewable. In the United States, meanwhile, historical applications of the fertilizer have polluted waterways. What accounts for these problems? It’s the soils, according to a new study comparing agriculture in the three countries.

PROVIDENCE, R.I. [Brown University] — Just 20 years ago, the soils of the Amazon basin were thought unsuitable for large-scale agriculture, but then industrial agriculture — and the ability to fertilize on a massive scale — came to the Amazon. What were once the poorest soils in the world now produce crops at a rate that rivals that of global breadbaskets. Soils no longer seem to be the driver — or the limiter — of agricultural productivity. But a new Brown University-led study of three soybean growing regions, including Brazil, finds that soils have taken on a new role: mediating the environmental consequences of modern farming. (more…)

Brown and High Schools: Teaching Teens About Climate Change, Health

By Guest PostDecember 14, 2012Educationallergies, anatomy course, breakthrough providence, brown university, climate change, curriculum, david upegui, ecology, evolutionary biology, global food supply, global warming, high school teachers, human health, infectious disease, jessica fields, katherine smith, mark schlissel, mold, name tags, natural habitat, pollen, tram bui, vicki santos silva

A Brown University class on the effect that climate change could have on human health has produced a free new curriculum for high school teachers. The nine-module unit, which reflects feedback from teachers, includes lecture background and ideas for warm-ups, in-class activities, and assessment.

PROVIDENCE, R.I. [Brown University] — Katherine Smith’s students had to wait until they came to Brown University to learn how climate change could affect human health. Now that Smith and her fall semester class have developed a rich new curriculum on the subject for high school teachers, future 10th to 12th graders might not have to wait so long.

The curriculum, a nine-module set of backgrounders, lecture notes and suggested lesson plans and classroom activities, is now available for free download. In 180 total pages, it covers topics ranging from an overview of climate change to more specific units such as how global warming could affect infectious disease, allergies, and the global food supply. (more…)

Mammalian Brain Knows Where It’s at

By Guest PostDecember 8, 2012Sciencebehavior, brain, brain injury, brown university, conventional wisdom, depression, disease, egocentric movement, electrical activity, fish sculpture, frequency, hippocampus, humans, journal, location, memory, neuron, neuropsychiatric diseases, neuroscientist, object, omar ahmed, parahippocampal cortex, pattern, phc, por, postrhinal cortex, primate neuroanatomy, rebecca burwell, region, rhythm, schizophrenia, sharon furtak, Space, spiking, theta, treat

A new study in the journal Neuron suggests that the brain uses a different region than neuroscientists had thought to associate objects and locations in the space around an individual. Knowing where this fundamental process occurs could help treat disease and brain injury as well as inform basic understanding of how the brain supports memory and guides behavior.

PROVIDENCE, R.I. [Brown University] — Where are you?

Conventional wisdom in brain research says that you just used your hippocampus to answer that question, but that might not be the whole story. The context of place depends on not just how you got there, but also the things you see around you. A new study in Neuron provides evidence that a different part of the brain is important for understanding where you are based on the spatial layout of the objects in that place. The finding, in rats, has a direct analogy to primate neuroanatomy. (more…)