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Scientists Chip Away at the Mystery of What Lives in Our Mouths

By Guest PostFebruary 27, 2014Scienceantibiotics, bacterium, biological dark matter, chip, clifford beall, daniel dayeh, DNA, eugene leys, forsythia, genome, mouths, mystery, pathogen, periodontitis, scientists, tannerella bu063, tannerella forsythia

Sequencing of harmless oral bacterium offers insights about its disease-causing relative

COLUMBUS, Ohio – Scientists have pieced together sections of DNA from 12 individual cells to sequence the genome of a bacterium known to live in healthy human mouths.

With this new data about a part of the body considered “biological dark matter,” the researchers were able to reinforce a theory that genes in a closely related bacterium could be culprits in its ability to cause severe gum disease. (more…)

Biotech Crops vs. Pests: Successes, Failures from the First Billion Acres

By Guest PostJune 11, 2013Environmentbacillus thuringiensis, bacterium, Beijing, biotech crops, bruce tabashnik, bt, bt crop acreage, bt toxins, cirad, epa, evolutionary theory, france, global assessment, insecticidal proteins, kongming wu, million hectares, organic farmers, pest resistance, pests, pink bollworm caterpillar, rapid evolution, resistance in pests, sprays, thierry brevault, university of arizona, world, yves carriere

A new global assessment helps scientists explain why genetically modified crops have suppressed some pests for longer than a decade, while others adapted in a few years.

Since 1996, farmers worldwide have planted more than 1 billion acres (400 million hectares) of genetically modified corn and cotton that produce insecticidal proteins from the bacterium Bacillus thuringiensis, or Bt for short.

Bt proteins, used for decades in sprays by organic farmers, kill some devastating pests but are considered environmentally friendly and harmless to people. However, some scientists feared that widespread use of these proteins in genetically modified crops would spur rapid evolution of resistance in pests. (more…)

Mutant Champions Save Imperiled Species from Almost-Certain Extinction

By Guest PostFebruary 25, 2013Scienceantibiotics, bacterium, benjamin kerr, changing environments, climate change, disease causing bacteria, e coli, environmental changes, environmental deterioration, escherichia coli, eth zurich, evolutionary adaptations, evolutionary rescue, extinction, extinction bullet, genes, genetic engineering, haley lindsey, heavy metals, high concentration environment, human caused changes, imperiled species, insects, jenna gallie, lower concentration, mutant champions, number of factors, overfishing, pesticides, population, populations of microorganisms, rapid rates, relay team, seattle, susan taylor, university of washington

Species facing widespread and rapid environmental changes can sometimes evolve quickly enough to dodge the extinction bullet. Populations of disease-causing bacteria evolve, for example, as doctors flood their “environment,” the human body, with antibiotics. Insects, animals and plants can make evolutionary adaptations in response to pesticides, heavy metals and overfishing.

Previous studies have shown that the more gradual the change, the better the chances for “evolutionary rescue” – the process of mutations occurring fast enough to allow a population to avoid extinction in changing environments. One obvious reason is that more individuals remain alive when change is gradual or moderate, meaning there are more opportunities for a winning mutation to emerge. (more…)

Virus Caught in the Act of Infecting a Cell

By Guest PostJanuary 12, 2013Health, Scienceaustin, bacterium, bo hu, cryo electron tomography, ct scan, e coli, experimental evidence, feelers, fibers, genetic, genetic material, head, human hair, ian molineux, image, infect, infect a cell, infected cell membrane, infection, infection process, jun liu, protein, protein path, robot like process, structure, t7, texas, thickness, university, ut health, viral dna, virus, visualize, william margolin

About the video: watch an animation showing the changes in the structure of a T7 virus as it infects an E. coli bacterium.

AUSTIN, Texas — The detailed changes in the structure of a virus as it infects an E. coli bacterium have been observed for the first time, report researchers from The University of Texas at Austin and The University of Texas Health Science Center at Houston (UT Health) Medical School this week in Science Express. (more…)

Deadly E. coli Strain Decoded

By Guest PostJuly 30, 2012Health, Science2011 outbreak, achilles heel, bacterium, biofilm, chris waters, e coli o157, e coli outbreak, e coli strain, german outbreak, Germany, michigan state university, o157 infection, shannon manning, shiga toxin, toxic gene

EAST LANSING, Mich. — The secret to the deadly 2011 E. coli outbreak in Germany has been decoded, thanks to research conducted at Michigan State University.

The deadliest E. coli outbreak ever, which caused 54 deaths and sickened more than 3,800 people, was traced to a particularly virulent strain that researchers had never seen in an outbreak before. In the current issue of the academic journal PLoS ONE, a team of researchers led by Shannon Manning, MSU molecular biologist and epidemiologist, suggests a way to potentially tame the killer bacteria. (more…)

Research Shows Why One Bacterial Infection is So Deadly in Cystic Fibrosis

By Guest PostApril 28, 2012Scienceacute infection, amal amer, antibiotics, anwari akhter, arwa abu khweek, autophagy, bacterial infection, bacterium, basant abdulrahman, benjamin kopp, burkholderia cenocepacia, cf, chronic destruction, cystic fibrosis, genetic mutation, kyle caution, lung infection, lung tissue, macrophage, mia tazi, mice and humans, molecule, ohio state university, p62, rapamycin

COLUMBUS, Ohio – Scientists have found why a certain type of bacteria, harmless in healthy people, is so deadly to patients with cystic fibrosis.

The bacterium, Burkholderia cenocepacia, causes a severe and persistent lung infection in patients with CF and is resistant to nearly all known antibiotics. Cystic fibrosis is a chronic disorder characterized by a buildup of mucus in the lungs and other parts of the body, and various types of lung infection are responsible for about 85 percent of deaths in these patients. (more…)

Russian Dolls of the Bug World

By Guest PostMarch 1, 2012Scienceacyrthosiphon pisum, aphid alarm pheromone, aphidius ervi, aphids, apse, bacteriophage, bacterium, battle for survival, environmental sciences, Europe, hamiltonella defense, hemolymph, insect, kerry oliver, martha molly hunter, North America, parasite and host, parasitic wasps, pea aphid, russian dolls, symbiont, trans b farnesene, university of arizona, virus, wasp larva

Parasitic wasps using tiny insects known as aphids as living nurseries for their brood can sniff out whether the host insect is protected by symbiotic bacteria, researchers have discovered.

A research team including Martha (Molly) Hunter from the department of entomology in the University of Arizona’s College of Agriculture of Life Sciences has disentangled relationships in an assembly of players that resemble Russian dolls: a bacterium that lives inside a tiny insect, a virus that infects those bacteria, and a parasitic wasp that lays its eggs in the insect.

In a war between parasite and host, the parasitic wasp, Aphidius ervi, and the pea aphid, Acyrthosiphon pisum, are locked in a battle for survival. (more…)

Studying The Evolution of Life’s Building Blocks

By Guest PostFebruary 20, 2012Sciencealbert szent gyorgyi, ancient life, bacterium, basic module, beginning of life, beginning of time, british columbia, building block, chemical building block, chemical reactions, evolution, evolution of life, geneticists, michigan state university, molecular complementarity, molecular paleontology, origin of life, paleontologists, physiologist, robert root bernstein, species, vancouver, vitamin c

VANCOUVER, British Columbia — Studying the origin of life at its building blocks offers a unique perspective on evolution, says a researcher at Michigan State University.

Robert Root-Bernstein, MSU physiology professor, will answer the question of why a physiologist studies the origin of life at the annual meeting of the American Association for the Advancement of Science Feb. 16-20 in Vancouver, British Columbia. (more…)

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