Category Archives: Science

Origin of Skillful Stone Tool Sharpening Method Pushed Back More Than 50,000 Years

A highly skillful and delicate method of sharpening and retouching stone artifacts by prehistoric people appears to have been developed at least 75,000 years ago, more than 50,000 years earlier than previously thought, according to a new study led by the University of Colorado at Boulder.

The new findings show that the technique, known as pressure flaking, took place at Blombos Cave in South Africa during the Middle Stone Age by anatomically modern humans and involved the heating of silcrete — quartz grains cemented by silica — used to make tools. Pressure flaking takes place when implements previously shaped by hard stone hammer strikes followed by softer strikes with wood or bone hammers are carefully trimmed on the edges by directly pressing the point of a tool made of bone on the stone artifact. (more…)

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Six New Isotopes of the Superheavy Elements Discovered

The discovery of six new isotopes, reaching in an unbroken chain of decays from element 114 down to rutherfordium, is a major step toward better understanding how to explore the region of enhanced stability thought to lie in the vicinity of element 114—and possibly beyond.” (more…)

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Knowledge of Genetic Cancer Risks Often Dies with Patients, Finds VCU Massey Cancer Center

Richmond, Va. – If you were dying from cancer, would you consider genetic testing? A recent study conducted by researchers from Virginia Commonwealth University Massey Cancer Center showed that most terminally ill cancer patients who were eligible for genetic testing never received it despite that it could potentially save a relative’s life.

The research, “Exploring Hereditary Cancer Among Dying Cancer Patients—A Cross-Sectional Study of Hereditary Risk and Perceived Awareness of DNA Testing and Banking,” was recently published in the Journal of Genetic Counseling, and is the first to document the prevalence of hereditary cancer risk and the need for genetic services and patient education among terminally ill cancer patients. (more…)

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Obesity: Yale Researcher Explains Why It’s All in Our Heads

Tamas Horvath. Image credit: Yale University

Tamas Horvath is the first to tell you that he doesn’t study obesity. But his research on the effects of metabolism on higher brain functions could provide deeper understanding of the brain’s link to appetite, weight and to metabolic disorders such as diabetes and obesity.

His lab was the first to provide evidence that the brain uses fat as fuel. Horvath has also studied how endocrine signals in the brain regulate neurodegenerative diseases such as Parkinson’s and Alzheimer’s.

Horvath followed his father and grandfather into veterinary medicine in his native Hungary, but his training sparked a passion for basic research. His achievements have earned him a long title that speaks to his varied research interests. He became chair of the Department of Comparative Medicine at Yale School of Medicine in 2005, and he is also a professor in the Departments of Obstetrics, Gynecology & Reproductive Sciences and Neurobiology. Horvath also heads the Program on Integrative Cell Signaling and the Neurobiology of Metabolism. (more…)

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Researchers Find ‘Goldilocks’ of DNA Self-Assembly

This image is a simulation snapshot of the molecular dynamics of DNA strands. Image credit: North Carolina State University

Researchers from North Carolina State University have found a way to optimize the development of DNA self-assembling materials, which hold promise for technologies ranging from drug delivery to molecular sensors. The key to the advance is the discovery of the “Goldilocks” length for DNA strands used in self-assembly – not too long, not too short, but just right.

DNA strands contain genetic coding that will form bonds with another strand that contains a unique sequence of complementary genes. By coating a material with a specific DNA layer, that material will then seek out and bond with its complementary counterpart. This concept, known as DNA-assisted self-assembly, creates significant opportunities in the biomedical and materials science fields, because it may allow the creation of self-assembling materials with a variety of applications.

But, while DNA self-assembly technology is not a new concept, it has historically faced some significant stumbling blocks. One of these obstacles has been that DNA segments that are too short often failed to self-assemble, while segments that are too long often led to the creation of deformed materials. This hurdle can lead to basic manufacturing problems, as well as significant changes in the properties of the material itself. (more…)

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Computer Modeling of Swimming Fish Could Lead To New Robots and Prosthetics

Image credit: University of Maryland

COLLEGE PARK, Md — Scientists at the University of Maryland and Tulane University have developed a computational model of a swimming fish that is the first to address the interaction of both internal and external forces on locomotion. The interdisciplinary research team simulated how the fish’s flexible body bends, depending on both the forces from the fluid moving around it as well as the muscles inside. Understanding these interactions, even in fish, will help design medical prosthetics for humans that work with the body’s natural mechanics, rather than against them. This research is published in the October 18, 2010 online early edition of the Proceedings of the National Academy of Sciences. (more…)

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Scary Chupacabras Monster is as Much Victim as Villain

ANN ARBOR, Mich.— As Halloween approaches, tales of monsters and creepy crawlies abound. Among the most fearsome is the legendary beast known as the chupacabras.

But the real fiend is not the hairless, fanged animal purported to attack and drink the blood of livestock; it’s a tiny, eight-legged creature that turns a healthy, wild animal into a chupacabras, says University of Michigan biologist Barry OConnor. (more…)

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X-Ray Diffraction May Play Key Role in Stopping ‘Kissing Bug,’ Fungus

John Tanner, who also teaches chemistry in the College of Arts and Science, is studying Aspergillus fumigatus. Image credit: University of Missouri

COLUMBIA, Mo. – If finding the cure for a fungus and parasite that affects millions of people were the subject of a detective show, University of Missouri Chemistry Professor John Tanner would be the forensic expert in the lab, using high-tech equipment to make a model that could eventually solve the crime.

Tanner, who also teaches chemistry in the College of Arts and Science, has joined forces with Pablo Sobrado, an assistant professor of biochemistry at Virginia Tech, to study a unique enzyme found on two “crime scenes”: in Aspergillus fumigatus, a fungus that causes pulmonary diseases in immuno-compromised people; and in a blood-sucking insect prevalent in South America and now being found in the southwestern U.S., called the Chagas parasite, also known as the “kissing bug” for the red welts left on the victims’ faces after being bitten in his or her sleep.

“My job is to figure out what the enzyme looks like using X-ray diffraction,” Tanner said. “This enzyme makes a special sugar molecule that these organisms need to survive, so if we can find a way to stop the reaction that makes that sugar, then we might find a way to kill these pathogens.” (more…)

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