Tag Archives: spectroscopy

Next Scientific Fashion Could be Designer Nanocrystals

Three University of Chicago chemistry professors hope that their separate research trajectories will converge to create a new way of assembling what they call “designer atoms” into materials with a broad array of potentially useful properties and functions.

These “designer atoms” would be nanocrystals—crystalline arrays of atoms intended to be manipulated in ways that go beyond standard uses of atoms in the periodic table. Such arrays would be suited to address challenges in solar energy, quantum computing and functional materials. (more…)

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Supernovae of the Same Brightness, Cut From Vastly Different Cosmic Cloth

Berkeley Lab researchers make historic observation of rare Type 1a Supernova

Exploding stars called Type 1a supernova are ideal for measuring cosmic distance because they are bright enough to spot across the Universe and have relatively the same luminosity everywhere. Although astronomers have many theories about the kinds of star systems involved in these explosions (or progenitor systems), no one has ever directly observed one—until now.

In the August 24 issue of Science, the multi-institutional Palomar Transient Factory (PTF) team presents the first-ever direct observations of a Type 1a supernova progenitor system. Astronomers have collected evidence indicating that the progenitor system of a Type 1a supernova, called PTF 11kx, contains a red giant star. They also show that the system previously underwent at least one much smaller nova eruption before it ended its life in a destructive supernova. The system is located 600 million light years away in the constellation Lynx. (more…)

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The Next Big Step Toward Atom-Specific Dynamical Chemistry

*Berkeley Lab scientists push chemistry to the edge, testing plans for a new generation of light sources*

For Ali Belkacem of Berkeley Lab’s Chemical Sciences Division, “What is chemistry?” is not a rhetorical question.

“Chemistry is inherently dynamical,” he answers. “That means, to make inroads in understanding – and ultimately control – we have to understand how atoms combine to form molecules; how electrons and nuclei couple; how molecules interact, react, and transform; how electrical charges flow; and how different forms of energy move within a molecule or across molecular boundaries.” The list ends with a final and most important question: “How do all these things behave in a correlated way, ‘dynamically’ in time and space, both at the electron and atomic levels?” (more…)

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New 3-D Model of RNA ‘Core Domain’ of Enzyme Telomerase May Offer Clues to Cancer, Aging

A model representation of telomerase's RNA "core domain," determined by Juli Feigon, Qi Zhang and colleagues in Feigon's UCLA laboratory. Image credit: Juli Feigon, UCLA Chemistry and Biochemistry/PNAS

Telomerase is an enzyme that maintains the DNA at the ends of our chromosomes, known as telomeres. In the absence of telomerase activity, every time our cells divide, our telomeres get shorter. This is part of the natural aging process, as most cells in the human body do not have much active telomerase. Eventually, these DNA-containing telomeres, which act as protective caps at the ends of chromosomes, become so short that the cells die.

 

But in some cells, such as cancer cells, telomerase, which is composed of RNA and proteins, is highly active and adds telomere DNA, preventing telomere shortening and extending the life of the cell. 

UCLA biochemists have now produced a three-dimensional structural model of the RNA “core domain” of the telomerase enzyme. Because telomerase plays a surprisingly important role in cancer and aging, understanding its structure could lead to new approaches for treating disease, the researchers say.  (more…)

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