Using a recently developed biomarker of aging known as an epigenetic clock, UCLA researchers working closely with a German team of investigators have found for the first time that obesity greatly accelerates aging of the liver. This finding could explain the early onset of many age-related diseases, including liver cancer, in people who are obese. (more…)
Researchers were able to improve walking and prolong survival in a mouse model by tweaking potassium levels
By boosting the ability of a specific type of cell to absorb potassium in the brain, UCLA researchers were able to improve walking and prolong survival in a mouse model of Huntington’s disease.
Their findings, published March 30 in the online edition of the journal Nature Neuroscience, could point to new drug targets for treating the devastating disease, which strikes one in every 20,000 Americans. (more…)
A team of researchers from UCLA’s Henry Samueli School of Engineering and Applied Science has developed a Google Glass application and a server platform that allow users of the wearable, glasses-like computer to perform instant, wireless diagnostic testing for a variety of diseases and health conditions.
With the new UCLA technology, Google Glass wearers can use the device’s hands-free camera to capture pictures of rapid diagnostic tests (RDTs), small strips on which blood or fluid samples are placed and which change color to indicate the presence of HIV, malaria, prostate cancer or other conditions. Without relying on any additional devices, users can upload these images to a UCLA-designed server platform and receive accurate analyses — far more detailed than with the human eye — in as little as eight seconds. (more…)
Black patients fare worst; Asians, Hispanics survive longest with disease
UCLA researchers have found that minority patients and those of lower socioeconomic status are far more likely to have advanced thyroid cancer when they are diagnosed with the disease than white patients and those in higher economic brackets.
In one of the most comprehensive studies of its kind, the UCLA team looked at nearly 26,000 patients with well-differentiated thyroid cancer and analyzed the impact of race and socioeconomic factors on the stage of presentation, as well as patient survival rates. (more…)
Temperatures in central China are 10 to 14 degrees Fahrenheit hotter today than they were 20,000 years ago, during the last ice age, UCLA researchers report — an increase two to four times greater than many scientists previously thought.
The findings, published on May 14, 2013, in the early online edition of the journal Proceedings of the National Academy of Sciences, could help researchers develop more accurate models of past climate change and better predict such changes in the future. (more…)
Opening the door to more sophisticated investigation of sperm locomotion and biophysics, researchers from UCLA’s Henry Samueli School of Engineering and Applied Science have identified previously unobserved swimming patterns in human and horse sperm cells.
This research, published in Scientific Reports, a journal of the Nature Publishing Group, could lead to a deeper understanding of how sperm move on their way to fertilization or other functions and how they react when encountering various toxins or chemicals. (more…)
Shipping lanes through the Arctic Ocean won’t put the Suez and Panama canals out of business anytime soon, but global warming will make these frigid routes much more accessible than ever imagined by melting an unprecedented amount of sea ice during the late summer, new UCLA research shows.
“The development is both exciting from an economic development point of view and worrisome in terms of safety, both for the Arctic environment and for the ships themselves,” said lead researcher Laurence C. Smith, a professor of geography at UCLA. (more…)
UCLA researchers, in a finding that runs counter to conventional wisdom, have discovered for the first time that a gene thought to express a stress-response protein in all cells that come under stress instead expresses the protein only in specific cell types.
The research team, from the Jules Stein Eye Institute at UCLA and the UCLA Division of Pulmonary and Critical Care Medicine, focused on αB-Crystallin, one of a class of molecules known as heat shock proteins, which are involved in the folding and unfolding of other proteins, helping them recover from stress so they can do their job. (more…)
