Yale scientists have solved a puzzle of the immune system: how antibodies enter the nervous system to control viral infections. Their finding may have implications for the prevention and treatment of a range of conditions, including herpes and Guillain-Barre syndrome, which has been linked to the Zika virus. (more…)
Berkeley Lab scientists have helped to develop a tiny chip that has big potential for quickly determining whether someone has been exposed to dangerous levels of ionizing radiation.
The first-of-its-kind chip has an array of nanosensors that measure the concentrations of proteins that change after radiation exposure.
Although still under development, the technology could lead to a hand-held device that “lights up” if a person needs medical attention in the aftermath of an incident involving radiation. Initial tests on mice found that the technology only requires a drop of blood, measures radiation dose in minutes, and yields results up to seven days after exposure. (more…)
Better diagnosis and treatment of cancer could hinge on the ability to better understand a single cell at its molecular level. New research offers a more comprehensive way of analyzing one cell’s unique behavior, using an array of colors to show patterns that could indicate why a cell will or won’t become cancerous.
A University of Washington team has developed a new method for color-coding cells that allows them to illuminate 100 biomarkers, a ten-time increase from the current research standard, to help analyze individual cells from cultures or tissue biopsies. The work is published this week (March 19) in Nature Communications. (more…)
The only way to protect against HIV and unintended pregnancy today is the condom. It’s an effective technology, but not appropriate or popular in all situations.
A University of Washington team has developed a versatile platform to simultaneously offer contraception and prevent HIV. Electrically spun cloth with nanometer-sized fibers can dissolve to release drugs, providing a platform for cheap, discrete and reversible protection. (more…)
A team of researchers from North Carolina State University and the Palo Alto Research Center (PARC) has found more evidence for the preservation of ancient dinosaur proteins, including reactivity to antibodies that target specific proteins normally found in bone cells of vertebrates. These results further rule out sample contamination, and help solidify the case for preservation of cells – and possibly DNA – in ancient remains.
Dr. Mary Schweitzer, professor of marine, earth and atmospheric sciences with a joint appointment at the North Carolina Museum of Natural Sciences, first discovered what appeared to be preserved soft tissue in a 67-million-year-old Tyrannosaurus Rex in 2005. Subsequent research revealed similar preservation in an even older (about 80-million-year-old)Brachylophosaurus canadensis. In 2007 and again in 2009, Schweitzer and colleagues used chemical and molecular analyses to confirm that the fibrous material collected from the specimens was collagen. (more…)
A current focus in global health research is to make medical tests that are not just cheap, but virtually free. One such strategy is to start with paper – one of humanity’s oldest technologies – and build a device like a home-based pregnancy test that might work for malaria, diabetes or other diseases.
A University of Washington bioengineer recently developed a way to make regular paper stick to medically interesting molecules. The work produced a chemical trick to make paper-based diagnostics using plain paper, the kind found at office supply stores around the world. (more…)
Pancreatic cancer is highly lethal and difficult to detect early. In a new study, researchers report that people who had high levels of antibodies for an infectious oral bacterium turned out to have double the risk for developing the cancer. High antibody levels for harmless oral bacteria, meanwhile, predicted a reduced pancreatic cancer risk.
PROVIDENCE, R.I. [Brown University] — A new study finds significant associations between antibodies for multiple oral bacteria and the risk of pancreatic cancer, adding support for the emerging idea that the ostensibly distant medical conditions are related.
The study of blood samples from more than 800 European adults, published in the journal Gut, found that high antibody levels for one of the more infectious periodontal bacterium strains of Porphyromonas gingivalis were associated with a two-fold risk for pancreatic cancer. Meanwhile, study subjects with high levels of antibodies for some kinds of harmless “commensal” oral bacteria were associated with a 45-percent lower risk of pancreatic cancer. (more…)
Since Adam and Eve, snakes have long been portrayed as evil creatures to be feared. Aboriginal groups in Australia hold the snake in high esteem, and it is a symbol of fertility. Native Americans in North America felt that snakes symbolized life cycles and truth.
