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Tenfold boost in ability to pinpoint proteins in cancer cells

By Guest PostMarch 23, 2013Healthantibodies, array of colors, biology, biomarkers, cancerous, cell behavior, cell function, characteristics, color coding cells, color fluorescence, cyclical testing, diagnosis, fluorescent balls, low ph fluid, molecular level, oncology, pathology, patterns, pavel zrazhevskiy, quantum dots, semiconductor material, single cell, Technology, tissue biopsies, treatment of cancer, university of washington, xiaohu gao

Better diagnosis and treatment of cancer could hinge on the ability to better understand a single cell at its molecular level. New research offers a more comprehensive way of analyzing one cell’s unique behavior, using an array of colors to show patterns that could indicate why a cell will or won’t become cancerous.

A University of Washington team has developed a new method for color-coding cells that allows them to illuminate 100 biomarkers, a ten-time increase from the current research standard, to help analyze individual cells from cultures or tissue biopsies. The work is published this week (March 19) in Nature Communications. (more…)

‘Bed-of-Nails’ Breast Implant Deters Cancer Cells

By Guest PostMarch 26, 2012Healthbed of nails, blood vessel, breast cancer, brown university, cancer tumor, cell, cell function, chemical analysis, electron spectroscopy, lijuan zhang, malignant, michael platek, nanoscale, Nanotechnology, plga, protein, regrowth, thomas webster, tumor, united states, university of rhode island, vegf

Researchers at Brown University have created an implant that appears to deter breast cancer cell regrowth. Made from a common federally approved polymer, the implant is the first to be modified at the nanoscale in a way that causes a reduction in the blood-vessel architecture that breast cancer tumors depend upon, while also attracting healthy breast cells. Results are published in Nanotechnology.

PROVIDENCE, R.I. [Brown University] — One in eight women in the United States will develop breast cancer. Of those, many will undergo surgery to remove the tumor and will require some kind of breast reconstruction afterward, often involving implants. Cancer is an elusive target, though, and malignant cells return for as many as one-fifth of women originally diagnosed, according to the American Cancer Society. (more…)

Mutated Gene Found in Dog Disease the Same in Humans, MU Researchers Find

By Guest PostApril 24, 2011Scienceanimal, cell function, columbia, dennis o’brien, dna test, fabiana farias, gary johnson, gene mutation, human neurological disorder, lynn steinhaus, man, martin katz, ncl, neuronal ceroid-lipofuscinosis, parkinson disease, seizures, tibetan terrier dogs, university of missouri

*Tibetian Terrier dogs could play key role in developing therapy for early-onset Parkinson’s*

COLUMBIA, Mo. – University of Missouri researchers believe both man and animal will benefit from their discovery that the same gene mutation found in Tibetan Terrier dogs can also be found in a fatal human neurological disorder related to Parkinson’s disease.

Fabiana Farias, a doctoral candidate in Area Genetics at the University of Missouri, found the mutation as part of her thesis research. Gary Johnson, associate professor of Veterinary Pathobiology; Martin Katz, professor of Veterinary Pathobiology, and Dennis O’Brien, a professor in the Department of Veterinary Medicine and Surgery, along with a host of researchers from MU’s College of Veterinary Medicine; College of Agriculture, Food and Natural Resources (CAFNR) and the Mason Eye Institute, recently published the findings in Neurobiology of Disease. (more…)

Tag Archives: cell function

Tenfold boost in ability to pinpoint proteins in cancer cells

‘Bed-of-Nails’ Breast Implant Deters Cancer Cells

Mutated Gene Found in Dog Disease the Same in Humans, MU Researchers Find