Tag Archives: seizures

Database Tracks Toxic Side Effects of Pharmaceuticals

Sometimes the cure can be worse than the disease. Pharmaceutical drugs are known for their potential side effects, and an important aspect of personalized medicine is to tailor therapies to individuals to reduce the chances of adverse events. Now researchers from North Carolina State University have updated an extensive toxicology database so that it can be used to track information about therapeutic drugs and their unintentional toxic effects.

“Environmental science actually shares a common goal with drug makers: to improve the prediction of chemical toxicity,” says Dr. Allan Peter Davis, lead author of a paper on the work and the biocuration project manager of the Comparative Toxicogenomics Database (CTD) in NC State’s Department of Biological Sciences. (more…)

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Mutated Gene Found in Dog Disease the Same in Humans, MU Researchers Find

*Tibetian Terrier dogs could play key role in developing therapy for early-onset Parkinson’s*

COLUMBIA, Mo. – University of Missouri researchers believe both man and animal will benefit from their discovery that the same gene mutation found in Tibetan Terrier dogs can also be found in a fatal human neurological disorder related to Parkinson’s disease.

Fabiana Farias, a doctoral candidate in Area Genetics at the University of Missouri, found the mutation as part of her thesis research. Gary Johnson, associate professor of Veterinary Pathobiology; Martin Katz, professor of Veterinary Pathobiology, and Dennis O’Brien, a professor in the Department of Veterinary Medicine and Surgery, along with a host of researchers from MU’s College of Veterinary Medicine; College of Agriculture, Food and Natural Resources (CAFNR) and the Mason Eye Institute, recently published the findings in Neurobiology of Disease. (more…)

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Facing the Migraine

Migraines are a chronic brain condition characterized by attacks of a throbbing headache, of medium or strong intensity, possibly associated with nausea, vomiting, photophobia and intolerance to sounds (phonophobia). In about a third of cases, seizures are accompanied by neurological symptoms, usually visual, known as auras. The disorder occurs in those who are genetically susceptible. The World Health Organization estimates that worldwide there are 324 million people who suffer from in this condition. (more…)

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