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CAD for RNA

By Guest PostDecember 27, 2011Scienceaptazyme, biodegradable plastics, biofuels, biological systems, cad, cad platforms, cad type models, cells, computer assisted design, control systems, darmawi juminaga, diabetes, e coli, escherichia coli bacterium, genetic circuits, genetic expression, james carothers, jay keasling, jbei, jonathan goler, lignocellulosic biomass, microbes, microbial fuel production, molecules, parkinson, petrochemicals, ribozyme, rna devices, rna functions, rna molecules, simulations, synberc, synthetic biology, tools, university of california

*Joint BioEnergy Institute Researchers Develop CAD-Type Tools for Engineering RNA Control Systems*

The computer assisted design (CAD) tools that made it possible to fabricate integrated circuits with millions of transistors may soon be coming to the biological sciences. Researchers at the U.S. Department of Energy (DOE)’s Joint BioEnergy Institute (JBEI) have developed CAD-type models and simulations for RNA molecules that make it possible to engineer biological components or “RNA devices” for controlling genetic expression in microbes. This holds enormous potential for microbial-based sustainable production of advanced biofuels, biodegradable plastics, therapeutic drugs and a host of other goods now derived from petrochemicals. (more…)

WISE Presents a Cosmic Wreath

By Guest PostDecember 26, 2011Sciencecosmic wreath, infrared survey, red cloud, wise

Just in time for the holidays, astronomers have come across a new image from NASA’s Wide-field Infrared Survey Explorer, or WISE, that some say resembles a wreath. You might even think of the red dust cloud as a cheery red bow, and the bluish-white stars as silver bells. This star-forming nebula is named Barnard 3. Baby stars are being born throughout the dusty region, while the “silver bell” stars are located both in front of, and behind, the nebula. (more…)

Altered Gene Tracks RNA Editing in Neurons

By Guest PostDecember 26, 2011Sciencealtered gene, gene expression, rna editing, rna repair, tracking adar

RNA editing is a key step in gene expression. Scientists at Brown University report in Nature Methods that they have engineered a gene capable of visually displaying the activity of the key enzyme ADAR in living fruit flies.

PROVIDENCE, R.I. [Brown University] — To track what they can’t see, pilots look to the green glow of the radar screen. Now biologists monitoring gene expression, individual variation, and disease have a glowing green indicator of their own: Brown University biologists have developed a “radar” for tracking ADAR, a crucial enzyme for editing RNA in the nervous system. (more…)

New Dye Will Lead To More Efficient Solar Energy Technology

By Guest PostDecember 25, 20111 commentScienceahmed el shafei, cellular phones, dsscs, dye sensitized solar cells, dyes, electrolyte, energy from light, facades, free electrons, laptop computers, mp3 players, nanoporous semiconductors, ncsu 10, north carolina state university, sensitizer, skylights, solar cells, solar light, Technology, tio2, titanium dioxide, windows

A North Carolina State University invention has significant potential to improve the efficiency of solar cells and other technologies that derive energy from light.

Dr. Ahmed El-Shafei’s research group invented a new “sensitizer,” or dye, that harvests more ambient and solar light than any dyes currently on the market for use in dye-sensitized solar cells (DSSCs). (more…)

New Tool Offers Unprecedented Access for Root Studies

By Guest PostDecember 25, 2011Sciencedevelopment of roots, plant roots, root studies, root system, rootchip

Stanford, CA — Plant roots are fascinating plant organs – they not only anchor the plant, but are also the world’s most efficient mining companies. Roots live in darkness and direct the activities of the other organs, as well as interact with the surrounding environment. Charles Darwin posited in The Power of Movement of Plants that the root system acts as a plant’s brain. (more…)

New Take on Impacts of Low Dose Radiation

By Guest PostDecember 24, 2011Health, Scienceatomic bomb blasts, berkeley lab, biological damage, breast cell line, broken dna, cancer risks, christopher pham, dna damage response, dna repair mechanisms, Environment, epidemiological data, extrapolation, gy of radiation, human breast cells, human tissue, ionizing radiation, Japan, joel swenson, lawrence berkeley national laboratory, levels of ionizing radiation, linear no threshold hypothesis, lnt, low dose radiation, mammogram, mathematical modeling, mcf10a, mina bissell, primary breast epithelial cells, radiation induced foci, rafael gomez sjoberg, repair, rif, standard model, survivors, sylvain costes, teresa neumaier, time lapse imaging, world war II, xray microbeam

*Berkeley Lab Researchers Find Evidence Suggesting Risk May Not Be Proportional to Dose at Low Dose Levels*

Researchers with the U.S. Department of Energy (DOE)’s Lawrence Berkeley National Laboratory (Berkeley Lab), through a combination of time-lapse live imaging and mathematical modeling of a special line of human breast cells, have found evidence to suggest that for low dose levels of ionizing radiation, cancer risks may not be directly proportional to dose. This contradicts the standard model for predicting biological damage from ionizing radiation – the linear-no-threshold hypothesis or LNT – which holds that risk is directly proportional to dose at all levels of irradiation.

“Our data show that at lower doses of ionizing radiation, DNA repair mechanisms work much better than at higher doses,” says Mina Bissell, a world-renowned breast cancer researcher with Berkeley Lab’s Life Sciences Division. “This non-linear DNA damage response casts doubt on the general assumption that any amount of ionizing radiation is harmful and additive.” (more…)

UCLA Physicists Report Nanotechnology Feat With Proteins

By Guest PostDecember 24, 2011Scienceatp, class of enzymes, elastic, enzyme, giovanni zocchi, gk, guanylate kinase, human hair, kinases, liquid, liquids flow, mechanical energy, mechanical response, nanomechanical measurements, nanometer, Nanotechnology, phosphate group, protein molecules, resolution, solid, stress, university of Illinois, visco elastic, visco elastic transition, viscoelastic behavior, viscoelastic regime, viscous, yong wang

UCLA physicists have made nanomechanical measurements of unprecedented resolution on protein molecules.

The new measurements, by UCLA physics professor Giovanni Zocchi and former UCLA physics graduate student Yong Wang, are approximately 100 times higher in resolution than previous mechanical measurements, a nanotechnology feat which reveals an isolated protein molecule, surprisingly, is neither a solid nor a liquid.

“Proteins are the molecular machines of life, the molecules we are made of,” Zocchi said. “We have found that sometimes they behave as a solid and sometimes as a liquid. (more…)

UChicago Chemist Helps Craft Message For World Leaders

By Guest PostDecember 23, 2011General, ScienceBangladesh, burundi, dmitri talapin, energy and environment, food and population, future development, Germany, global necessity, global warming, Health, Japan, kyoto, kyoto protocol, mass media, megacities, nigeria, nobel laureates, North America, nuclear safety, positive and negative aspects, reverse osmosis membrane, science and technology, scientific information, scientific research, singapore, social media, steve koppes, sts forum, sustainability, the netherlands, water shortage, young scientists

Dmitri Talapin, associate professor in chemistry, was one of 10 young scientists from around the world who delivered a message that “Scientific Research is a Global Necessity” to political, scientific and business leaders participating in the 2011 Science and Technology in Society forum last October in Kyoto, Japan.

The Japan Society for the Promotion of Science and the New York Academy of Sciences selected Talapin to represent the young scientists of North America at the STS Forum, which meets at the same venue were the Kyoto Protocol to alleviate global warming was signed in 1997. (more…)

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