“The more I focus on my thoughts, the more I feel like they don’t belong to me” — that is how Anna, an individual with psychosis, describes her experience.
This disruption in a person’s sense of self has long fascinated Rachel Aviv, staff writer for The New Yorker, she said in a recent campus talk sponsored by the Poynter Fellowship in Journalism. (more…)
ANN ARBOR — Sooner or later, everyone faces decisions about whether or not to have surgery, take a new medication or have a cancer-screening test.
A new University of Michigan study published in Health Expectations explores the costs and benefits patients say are important in making these kinds of medical decisions, and how those costs and benefits explain what they actually decide to do. (more…)
The science behind the tingling sensation caused by eating a popular Asian spice has been explained by researchers at UCL.
The study, which is published in the journal Proceedings of the Royal Society B, helps shed light on the complex interactions between the senses of taste and touch, and could lead to a greater understanding of the causes of the tingling sensations experienced by many chronic pain patients.
Widely used in Asian cooking, the Szechuan pepper was found to mimic the sense of touch in the brain. It chemically activates light-touch fibres on the lips and tongue and sends the equivalent of 50 light taps to the brain per second. (more…)
Improvement enables ‘liquid biopsies’ for metastatic melanoma
Researchers at UCLA report that they have refined a method they previously developed for capturing and analyzing cancer cells that break away from patients’ tumors and circulate in the blood. With the improvements to their device, which uses a Velcro-like nanoscale technology, they can now detect and isolate single cancer cells from patient blood samples for analysis.
Circulating tumor cells, or CTCs, play a crucial role in cancer metastasis, spreading from tumors to other parts of the body, where they form new tumors. When these cells are isolated from the blood early on, they can provide doctors with critical information about the type of cancer a patient has, the characteristics of the individual cancer and the potential progression of the disease. Doctors can also tell from these cells how to tailor a personalized treatment to a specific patient. (more…)
As cancer treatment in pill form transforms how care is delivered, a new Michigan State University study underscores the challenges patients face in administering their own chemotherapy outside the supervised environment of a cancer clinic.
Chemotherapy pills can target specific cancers better than some traditional intravenous drugs, said Sandra Spoelstra, the MSU assistant professor of nursing who led the study. But they also can be difficult for patients to take. (more…)
Like cleaning the lenses of a foggy pair of glasses, scientists are now able to use a technique developed by UCLA researchers and their European colleagues to produce three-dimensional images of breast tissue that are two to three times sharper than those made using current CT scanners at hospitals. The technique also uses a lower dose of X-ray radiation than a mammogram.
These higher-quality images could allow breast tumors to be detected earlier and with much greater accuracy. One in eight women in the United States will be diagnosed with breast cancer during her lifetime.
The research is published the week of Oct. 22 in the early edition of the journal Proceedings of the National Academy of Sciences. (more…)
Health practitioners should use behavior-change tactics so patients take medications as prescribed
COLUMBIA, Mo. – Nearly half of patients taking medications for chronic conditions do not strictly follow their prescribed medication regimens. Failure to use medications as directed increases patients’ risk for side effects, hospitalizations, reduced quality of life and shortened lifespans. Now, a University of Missouri gerontological nursing expert says patients’ poor adherence to prescribed medication regimens is connected to their beliefs about the necessity of prescriptions and concerns about long-term effects and dependency.
MU Assistant Professor Todd Ruppar found that patients’ beliefs about the causes of high blood pressure and the effectiveness of treatment alternatives significantly affected their likelihood of faithfully following prescribed medication regimens. In his pilot study, Ruppar focused on older patients’ adherence to medication treatments that control high blood pressure, a condition that affects nearly 70 million adults in the U.S. and can lead to heart disease and stroke. (more…)
Doctors can improve treatment programs using this knowledge
COLUMBIA, Mo. – The human immunodeficiency virus (HIV) can contain dozens of different mutations, called polymorphisms. In a recent study an international team of researchers, including University of Missouri scientists, found that one of those mutations, called 172K, made certain forms of the virus more susceptible to treatment. Soon, doctors will be able to use this knowledge to improve the drug regimen they prescribe to HIV-infected individuals.
“The 172K polymorphism makes certain forms of HIV less resistant to drugs,” said Stefan Sarafianos, corresponding author of the study and a researcher at MU’s Bond Life Sciences Center. “172K doesn’t affect the virus’ normal activities. In some varieties of HIV that have developed resistance to drugs, when the 172K mutation is present, resistance to two classes of anti-HIV drugs is suppressed. We estimate up to 3 percent of HIV strains carry the 172K polymorphism.” (more…)
