Category Archives: Health

MU Researcher’s Photoacoustic Device Finds Cancer Cells Before They Become Tumors

*Commercial production will allow scientists, academia opportunity for use in cancer studies*

COLUMBIA, Mo. – Early detection of melanoma, the most aggressive skin cancer, is critical because melanoma will spread rapidly throughout the body. Now, University of Missouri researchers are one step closer to melanoma cancer detection at the cellular level, long before tumors have a chance to form. Commercial production of a device that measures melanoma using photoacoustics, or laser-induced ultrasound, will soon be available to scientists and academia for cancer studies. The commercial device also will be tested in clinical trials to provide the data required to obtain U.S. Food and Drug Administration approval for early diagnosis of metastatic melanoma and other cancers. (more…)

Read More

Ovarian Cancer Study Proves Drug Delays Disease Progression

*U of T, U.K. study focused on Avastin*

Treating ovarian cancer with the drug bevacizumab (“Avastin”) delays the disease and may also improve survival, according to an international clinical trial co-led by Drs. Amit Oza of the University of Toronto and Princess Margaret Hospital (PMH) and Timothy Perren of St James’s Institute of Oncology, Leeds, U.K.

The findings, published on Dec. 28 in the New England Journal of Medicine, report that the drug halted the cancer’s return for two months overall. However, for women with the highest risk disease, the delay was five to six months and in this group, the findings also indicate a strong trend to improved overall survival, which is being analysed until 2013. (more…)

Read More

People Don’t Just Think with Their Guts; Logic Plays a Role Too

For decades, science has suggested that when people make decisions, they tend to ignore logic and go with the gut. But Wim De Neys, a psychological scientist at the University of Toulouse in France, has a new suggestion: Maybe thinking about logic is also intuitive. He writes about this idea in the January issue of Perspectives on Psychological Science, a journal of the Association for Psychological Science. (more…)

Read More

Andrew Artenstein: Essential Enzymes Key to Disease, Maybe Treatments

*Proprotein convertases are enzymes that activate many essential proteins, but they are also implicated in many processes that cause disease. In a research review in the New England Journal of Medicine, Andrew Artenstein and Steven Opal argue that proprotein convertases are potentially rich targets for developing therapies.*

Most people have never heard of proprotein convertases, but the enzymes activate many proteins that are essential for life. Unfortunately, their fundamental role puts them in the middle of many processes that cause disease – not just cancer or athlerosclerosis, but both of those and Alzheimer’s and anthrax and the flu and an amazing variety of other maladies.

In a research review article appearing Dec. 29 in the New England Journal of Medicine, Andrew Artenstein, physician-in-chief in the Department of Medicine at Memorial Hospital, and Steven Opal, chief of infectious diseases at Memorial Hospital, argue that proprotein convertases (PCs) are potentially rich targets for developing therapies. Artenstein, who with Opal is on the faculty of the Warren Alpert School of Medicine, explained PCs to David Orenstein. (more…)

Read More

Breast Cancer Survivors Benefit From Practicing Mindfulness-Based Stress Reduction, MU Researchers Find

*Survivors’ psychological and physiological health improved after training*

COLUMBIA, Mo. – Women recently diagnosed with breast cancer have higher survival rates than those diagnosed in previous decades, according to the American Cancer Society. However, survivors continue to face health challenges after their treatments end. Previous research reports as many as 50 percent of breast cancer survivors are depressed. Now, University of Missouri researchers in the Sinclair School of Nursing say a meditation technique can help breast cancer survivors improve their emotional and physical well-being. (more…)

Read More

“Painless” Plasma Brush is Becoming Reality in Dentistry, MU Engineers Say

*Hi-tech dental instrument uses “cool flame” for sturdier and longer-lasting fillings*

COLUMBIA, Mo. – University of Missouri engineers and their research collaborators at Nanova, Inc. are one step closer to a painless way to replace fillings. After favorable results in the lab, human clinical trials are underway on the “plasma brush.” (more…)

Read More

New Take on Impacts of Low Dose Radiation

*Berkeley Lab Researchers Find Evidence Suggesting Risk May Not Be Proportional to Dose at Low Dose Levels*

Researchers with the U.S. Department of Energy (DOE)’s Lawrence Berkeley National Laboratory (Berkeley Lab), through a combination of time-lapse live imaging and mathematical modeling of a special line of human breast cells, have found evidence to suggest that for low dose levels of ionizing radiation, cancer risks may not be directly proportional to dose. This contradicts the standard model for predicting biological damage from ionizing radiation – the linear-no-threshold hypothesis or LNT – which holds that risk is directly proportional to dose at all levels of irradiation.

“Our data show that at lower doses of ionizing radiation, DNA repair mechanisms work much better than at higher doses,” says Mina Bissell, a world-renowned breast cancer researcher with Berkeley Lab’s Life Sciences Division. “This non-linear DNA damage response casts doubt on the general assumption that any amount of ionizing radiation is harmful and additive.” (more…)

Read More