Category Archives: Health

In Lab, Pannexin1 Restores Tight Binding of Cells Lost in Cancer

By studying tumor cell behavior in a novel “scaffold-free” 3-D system, researchers have determined that the protein Pannexin1 may play an important biomechanical role in binding tissues together, an effect that is lost in cancerous cells

PROVIDENCE, R.I. [Brown University] — First there is the tumor and then there’s the horrible question of whether the cancerous cells will spread. Scientists increasingly believe that the structural properties of the tumor itself, such as how tightly the tumor cells are packed together, play a decisive role in the progression of the disease. In a new study, researchers show that the protein Pannexin1, known to have tumor-suppressive properties, plays an important role in keeping the cells within a tissue closely packed together, an effect that may be lost with cancer. (more…)

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They Know The Drool

*The search for biomarkers of disease in spit*

It’s a researcher’s dream: a simple, noninvasive test to detect life-threatening cancer, heart disease, or other maladies while they’re still treatable.

A team of University of Minnesota researchers is in hot pursuit of that goal, using one of the simplest means imaginable: testing spit. They’ve discovered that conditions such as breast and oral cancer leak certain proteins into saliva, and if detected, such proteins can be “biomarkers” for the disease. (more…)

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Researchers Suggest A Proximate Cause of Cancer

AUSTIN, TX — Researchers from The University of Texas at Austin’s Department of Chemical Engineering are the first to show that mechanical property changes in cells may be responsible for cancer progression — a discovery that could pave the way for new approaches to predict, treat and prevent cancer. (more…)

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Young Breast Cancer Survivors Face Serious Quality-of-Life Challenges

Researchers seek ways to address long-term effects of treatment

Quality of life in younger patients treated for breast cancer is seriously compromised, and these women face more physical and mental health issues than women their age who haven’t had cancer and women over 50 who have, according to a study by researchers at UCLA’s Jonsson Comprehensive Cancer Center. (more…)

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Vision Improves Modestly in Patients after Human Embryonic Stem Cells Transplants

Researchers at UCLA’s Jules Stein Eye Institute and colleagues who successfully transplanted specialized retinal cells derived from human embryonic stem cells into the eyes of two legally blind patients report that the transplants appear safe and that both patients have experienced modest improvement in their vision.

The preliminary findings, published online Jan. 23 in the journal The Lancet, represent a milestone in the therapeutic use of stem cells and may pave the way for a new therapy to treat eye diseases, the researchers said. Because this is the first time physicians have applied the power of regenerative medicine to eye disease, the clinical trials are being watched closely by scientists, stem-cell therapy advocates and the public. (more…)

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