Category Archives: Health

Lecture or Listen: When Patients Waver on Meds

*According to a new analysis of hundreds of recorded office visits, doctors and nurse practitioners typically issued orders and asked closed or leading questions when talking to their HIV-positive patients about adherence to antiretroviral therapy. Attempts at problem-solving with patients who had lapsed occurred in less than a quarter of visits.*

PROVIDENCE, R.I. [Brown University] — Take your medicine, Doctor’s orders. It’s a simple idea that may seem especially obvious when the pills are the antiretroviral (ARV) drugs that add decades to the lives of HIV-positive patients. But despite the reality that keeping up with drug regimens is not easy for many patients, a new analysis of hundreds of recorded doctor’s office visits finds that physicians and nurse practitioners often still rely on lecturing, ordering, and scolding rather than listening and problem solving with their patients. (more…)

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UF Research: Blueberry Wine Has More Antioxidants than Many Grape-Based Wines

GAINESVILLE, Fla. — Blueberry wine can provide more potentially healthy compounds than white wines and many red wines, according to a new University of Florida study.

Researchers with UF’s Institute of Food and Agricultural Sciences measured antioxidant content in a Florida-produced blueberry wine and compared it to published reports of antioxidant content in white and red wines made from grapes. Antioxidants are compounds that may offer cells protection from damaging molecules called free radicals. (more…)

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In Lab, Pannexin1 Restores Tight Binding of Cells Lost in Cancer

*By studying tumor cell behavior in a novel “scaffold-free” 3-D system, researchers have determined that the protein Pannexin1 may play an important biomechanical role in binding tissues together, an effect that is lost in cancerous cells.*

PROVIDENCE, R.I. [Brown University] — First there is the tumor and then there’s the horrible question of whether the cancerous cells will spread. Scientists increasingly believe that the structural properties of the tumor itself, such as how tightly the tumor cells are packed together, play a decisive role in the progression of the disease. In a new study, researchers show that the protein Pannexin1, known to have tumor-suppressive properties, plays an important role in keeping the cells within a tissue closely packed together, an effect that may be lost with cancer.

“In healthy tissues, the recently discovered protein Pannexin1 may be playing an important role in upholding the mechanical integrity of the tissue,” said first author and Brown University M.D./Ph.D. student Brian Bao. “When we develop cancer, we lose Pannexin1 and we lose this integrity.” (more…)

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They Know The Drool

*The search for biomarkers of disease in spit*

It’s a researcher’s dream: a simple, noninvasive test to detect life-threatening cancer, heart disease, or other maladies while they’re still treatable.

A team of University of Minnesota researchers is in hot pursuit of that goal, using one of the simplest means imaginable: testing spit. They’ve discovered that conditions such as breast and oral cancer leak certain proteins into saliva, and if detected, such proteins can be “biomarkers” for the disease. (more…)

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Researchers Suggest A Proximate Cause of Cancer

AUSTIN, TX — Researchers from The University of Texas at Austin’s Department of Chemical Engineering are the first to show that mechanical property changes in cells may be responsible for cancer progression — a discovery that could pave the way for new approaches to predict, treat and prevent cancer.

Postdoctoral student Parag Katira and his adviser, Roger T. Bonnecaze, department chair in the Cockrell School of Engineering and T. Brockett Hudson Professor, worked with Muhammad Zaman of Boston University to devise a 3-D cancer model that shows the softening of cells and changes in cell binding cause cancerous behavior in cells. These mechanical property changes cause cells to divide uncontrollably — making them less likely to die and resulting in malignant tumor growth. The findings present a unique physics-based perspective on understanding cancer progression and were published recently in the American Physical Society’s journal Physical Review Letters. (more…)

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