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Gold Nanoparticle Prostate Cancer Treatment Found Safe in Dogs, MU Study Shows

By Guest PostOctober 16, 2012Healthancer death, bodily function, cancer, cancer patient, cause, chemotherapy, clinical trial, dose, efficient way, gold nanoparticle, human patient, kattesh katti, missouri, mizzou advantage, one health, one medicine area, prostate cancer, prostate tumor, radioactive, reduction, sandra axiak bechtel, side effect, toxic, travel, treatment, tumor, tumor volume, university, us men, vital organ

New treatment may have fewer side effects than traditional cancer therapy

COLUMBIA, Mo. — Currently, large doses of chemotherapy are required when treating certain forms of cancer, resulting in toxic side effects. The chemicals enter the body and work to destroy or shrink the tumor, but also harm vital organs and drastically affect bodily functions. Now, scientists at the University of Missouri have proven that a new form of prostate cancer treatment that uses radioactive gold nanoparticles, and was developed at MU, is safe to use in dogs. Sandra Axiak-Bechtel, an assistant professor in oncology at the MU College of Veterinary Medicine, says that this is a big step for gold nanoparticle research.

“Proving that gold nanoparticles are safe to use in the treatment of prostate cancer in dogs is a big step toward gaining approval for clinical trials in men,” Axiak-Bechtel said. “Dogs develop prostate cancer naturally in a very similar way as humans, so the gold nanoparticle treatment has a great chance to translate well to human patients.” (more…)

Immune Systems of ‘Bubble Babies’ Restored by Gene Therapy, UCLA Researchers Find

By Guest PostSeptember 14, 2012Healthada deficient, adenosine deaminase, bone marrow, bubble boy, chemotherapy, chronic diarrhea, denise carbonaro sarracino, disease, donald kohn, ear infections, enzyme, gene therapy, immune system, immunology, microbiology, molecular genetics, oral candidiasis, recurrent pneumonia, researcher, scid, stem cell, sterile environment, treatment, ucla, virus

UCLA stem cell researchers have found that a gene therapy regimen can safely restore immune systems to children with so-called “bubble boy” disease, a life-threatening condition that if left untreated can be fatal within one to two years.

In the 11-year study, researchers were able to test two therapy regimens for 10 children with ADA-deficient severe combined immunodeficiency (SCID), which has come to be known as “bubble boy” disease because some of its victims have been forced to live in sterile environments. (more…)

Gold Nanoparticles Could Treat Prostate Cancer With Fewer Side Effects than Chemotherapy, MU Researchers Find

By Guest PostJuly 20, 2012Healthcurrent therapy, gold nanoparticles, prostate cancer, prostate tumors, treatment

In new study published in PNAS, scientists found that nanoparticles, produced from chemicals in tea, reduced tumors by 80 percent

COLUMBIA, Mo. – Currently, large doses of chemotherapy are required when treating certain forms of cancer, resulting in toxic side effects. The chemicals enter the body and work to destroy or shrink the tumor, but also harm vital organs and drastically affect bodily functions. Now, University of Missouri scientists have found a more efficient way of targeting prostate tumors by using gold nanoparticles and a compound found in tea leaves. This new treatment would require doses that are thousands of times smaller than chemotherapy and do not travel through the body inflicting damage to healthy areas. The study is being published in the Proceedings of the National Academy of Science. (more…)

Biosensor Illuminates Compounds to Aid Fight Against TB

By Guest PostMay 16, 2012Scienceagbioresearc, antibiotics, biosensor, chris wilson, chronic infection, chronic tb, drug resistant, drug therapy, environmental oxygen, global health, glows green, grand challenges explorations, immunization, infection, nutrition, oxygen sensing system, robert abramovitch, synthetic biosensor, tb, tb bacterium, treatment, tuberculosis, tuberculosis epidemic

EAST LANSING, Mich. — For his work on developing new treatments for tuberculosis, a Michigan State University researcher has been named a Grand Challenges Explorations winner, an initiative funded by the Bill & Melinda Gates Foundation.

Robert Abramovitch of MSU’s Department of Microbiology and Molecular Genetics is using a synthetic biosensor that glows green in response to conditions that mimic human tuberculosis infection. He will screen for compounds that target chronic TB infection and may help shorten therapy or treat multidrug-resistant TB, which does not respond well to existing antibiotics. (more…)

Guidelines for Prostate Screening Widely Ignored, Study Finds

By Guest PostApril 25, 2012Healthberkshire hathaway, blood test, cancer specific mortality, ceo, controversial decision, data, dezheng huo, diagnosis, jim hu, john easton, los angeles, michael drazer, nhis, prostate cancer, prostate specific antigen, psa, psa screening, recommendation, sandip prasad, scott eggener, treatment, university of california, university of chicago, warren buffett

2008 recommendations from federal task force had no impact

New research confirms that the controversial decision by Warren Buffett – the 81-year-old CEO of Berkshire Hathaway – to undergo a blood test screening for prostate cancer despite his age is hardly unusual. Despite recommendations in 2008 from the United States Preventive Services Task Force against testing for prostate cancer in men aged 75 years or older, almost half of men in that age group continue to get screening tests.

In 2005, before the recommendations were released, 43 percent of men age 75 and above elected to take the prostate-specific antigen (PSA) test. In August 2008, the Task Force stated it “recommends against the service,” arguing “there is moderate or high certainty the service has no net benefit or that the harms outweigh the benefits.” (more…)

Nano-Sized Protein Clusters Address Major Challenge of Drug Delivery

By Guest PostFebruary 2, 2012Sciencearthritis, austin, biopharmaceutical, bloodstream, cancer, cockrell school, dilute concentration, diseases, infectious disease, jennifer maynard, keith p johnston, packard foundation, ph, protein, protein nanocluster, thomas truskett, treatment, universal approach, university of texas, welch foundation

AUSTIN, TX — A new form of proteins discovered by researchers at The University of Texas at Austin could drastically improve treatments for cancer and other diseases, as well as overcome some of the largest challenges in therapeutics: delivering drugs to patients safely, easily and more effectively.

The protein formulation strategy, discovered by chemical engineering faculty members and students in the Cockrell School of Engineering, is unprecedented and offers a new and universal approach to drug delivery — one that could revolutionize treatment of cancer, arthritis and infectious disease. (more…)

Laborers of Love

By Guest PostNovember 26, 2011Sciencehominins, horned owl, injured birds, treatment

Three volunteers who make a difference

A murmur runs through the audience as Bob Kriel withdraws his gloved hand from a darkened cage in the front of a small lecture room. (more…)

Brain Imaging Technique: New Hope for Understanding Parkinson’s Disease

By Guest PostMarch 2, 2011Health, Sciencebasal ganglia, biomedical engineering, brain imaging technique, brain oscillations, disease progression, l dopa, medication, mri, neural oscillations, neurology, parkinsons disease, patients, placebo pill, rachael seidler, radiology, ripple in the pond, scott peltier, symptoms, treatment, youngbin kwak

ANN ARBOR, Mich.— A non-invasive brain imaging technique gives new hope to patients with Parkinson’s disease in finding new and better treatment plans and tracking the disease progression, a new University of Michigan study shows.

The technique uses an MRI to measure resting state brain activity oscillations, said Rachael Seidler, associate professor in the School of Kinesiology and the Department of Psychology, and study author. (more…)

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