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Berkeley Lab Startup Wants to Know How Damaged Your DNA Is

By Guest PostMarch 6, 2014Health, Technologyaging, berkeley lab startup, cancer, chemical spill, damage, DNA, dna damage, dna repair, double strand breaks, elk river, environmental event, exogen, genetics, immunity, jonathan tang, NASA, repair, scid, severe combined immunodeficiency, steve yannone, sylvain costes, west virginia

Exogen can check the DNA health not only of an individual but that of an entire region, thus answering questions on the impact of environmental events.

Currently if a scientist or doctor wanted to measure the level of a person’s DNA damage, they would have to look at some cells in a fluorescent microscope and manually count the number of DNA breaks. This kind of counting is labor-intensive, time-consuming, and a highly subjective process. Lawrence Berkeley National Laboratory (Berkeley Lab) scientist Sylvain Costes, who has spent over a decade studying the effects of low-dose radiation on cellular processes, came up with a way to automate the job using a proprietary algorithm and a machine to scan specimens and objectively score the damaged DNA. (more…)

Immune Systems of ‘Bubble Babies’ Restored by Gene Therapy, UCLA Researchers Find

UCLA stem cell researchers have found that a gene therapy regimen can safely restore immune systems to children with so-called “bubble boy” disease, a life-threatening condition that if left untreated can be fatal within one to two years.

In the 11-year study, researchers were able to test two therapy regimens for 10 children with ADA-deficient severe combined immunodeficiency (SCID), which has come to be known as “bubble boy” disease because some of its victims have been forced to live in sterile environments. (more…)

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Berkeley Lab Startup Wants to Know How Damaged Your DNA Is

Immune Systems of ‘Bubble Babies’ Restored by Gene Therapy, UCLA Researchers Find