Cryo electron microscope enables scientists to explore the frontiers of targeted antibiotics
Researchers at UCLA’s California NanoSystems Institute have become the first to produce images of the atomic structures of three specific biological nanomachines, each derived from a different potentially deadly bacterium — an achievement they hope will lead to antibiotics targeted toward specific pathogens. (more…)
The hepatitis C virus has a previously unrecognized tactic to outwit antiviral responses and sustain a long-term infection. It also turns out that some people are genetically equipped with a strong countermeasure to the virus’ attempt to weaken the attack on it.
The details of these findings suggest potential targets for treating HCV, according to a research team led by Dr. Ram Savan, assistant professor of immunology at the University of Washington. The study was published in Nature Immunology. (more…)
UCLA stem cell researchers have found that a gene therapy regimen can safely restore immune systems to children with so-called “bubble boy” disease, a life-threatening condition that if left untreated can be fatal within one to two years.
In the 11-year study, researchers were able to test two therapy regimens for 10 children with ADA-deficient severe combined immunodeficiency (SCID), which has come to be known as “bubble boy” disease because some of its victims have been forced to live in sterile environments. (more…)
ANN ARBOR, Mich.—Tuberculosis fights off the toxic agents, acidity and oxidants, that our immune system sends to destroy it, which is why the maddeningly drug-resistant bacterium can survive in harsh conditions in our bodies for essentially as long as its human host lives, new research shows. (more…)
