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One-two punch could be key in treating blindness

By Guest PostMay 1, 2013Scienceachromatopsia, andras komaromy, blindness, central nervous system, cntf, fido, humans, michigan state university, model disease, molecular therapy, most younger dogs, photoreceptors, protein, treatment, university of miami, veterinary ophthalmologist

Researchers have discovered that using two kinds of therapy in tandem may be a knockout combo against inherited disorders that cause blindness. While their study focused on man’s best friend, the treatment could help restore vision in people, too.

Published in the journal Molecular Therapy, the study builds on earlier work by Michigan State University veterinary ophthalmologist András Komáromy and colleagues. In 2010, they restored day vision in dogs suffering from achromatopsia, an inherited form of total color blindness, by replacing the mutant gene associated with the condition. (more…)

Study Shows How Vitamin E Can Help Prevent Cancer

By Guest PostMarch 30, 2013Healthakt, anti cancer effect, anti cancer property, cancer cell survival, cancer prevention, chemical analysis, ching shih chen, enzyme, formulation, gujarat, hao chieh chiu, India, mutation, naval kapuriya, optimize, phlpp1, prevent cancer, protein, pten gene, saurashtra university, tocopherols, treatment, tumor cell death, vitamin e

COLUMBUS, Ohio – Researchers have identified an elusive anti-cancer property of vitamin E that has long been presumed to exist, but difficult to find.

Many animal studies have suggested that vitamin E could prevent cancer, but human clinical trials following up on those findings have not shown the same benefits. (more…)

Peer support shows promise in epilepsy fight

By Guest PostMarch 28, 2013General, Healthchildren, debilitating stigma, developing world, epilepsy, epilepsy in africa, epilepsy patients, epilepsy related stigma, epileptic seizures, gretchen birbeck, melissa elafros, michigan state university, peer support groups, treatment, village of chikankata, zambia

Peer support groups show promise for combating the debilitating stigma that surrounds epilepsy in much of the developing world, according to a new study led by a Michigan State University medical student.

The researchers report in the journal Epilepsy and Behavior that young people with the disease felt significantly less stigmatized after meeting regularly to discuss their illness. (more…)

Few Pregnant Women Treated for Sexually Transmitted Infections

By Guest PostFebruary 14, 2013Healthantibiotics, cdc, chlamydia, cynthia gardiner, david whalen, diagnosis, drug resistant organisms, ectopic pregnancy, gonorrhea, grand rapids, infections, jeffrey jones, medical guidelines, michigan state university, pelvic inflammatory disease, pregnant women, risk of infertility, roman krivochenitser, sexually transmitted infections, signs of pregnancy, treatment

Many pregnant women with sexually transmitted infections aren’t getting the treatment they need when they visit emergency rooms, according to a new Michigan State University study that highlights a wholly preventable risk to unborn children and raises questions about current medical guidelines.

About half of the 735 women with gonorrhea or chlamydia who visited the ERs at three hospitals in Grand Rapids, Mich. from 2008 through 2010 did not get treatment there, despite the availability of effective and relatively inexpensive antibiotics. Of the 179 who were pregnant, only 20 percent received treatment in the ER. (more…)

Costly Breast Cancer Screenings Don’t Add up to Better Outcomes

By Guest PostJanuary 22, 2013Healthanees chagpar, breast cancer, breast cancer incidence, brigid killelea, cary gross, copper team, cost of screening, geographic regions, heather gold, jama network publication, jessica long, joseph ross, mammography, maysa abu khalaf, medicine, rong wang, screenings, treatment, united states, variation, xiaomei ma, yale cancer center, yale school

Even though Medicare spends over $1 billion per year on breast cancer screenings such as a mammography, there is no evidence that higher spending benefits older women, researchers at Yale School of Medicine found in a study published Online First by JAMA Internal Medicine, a JAMA Network publication.

Led by Dr. Cary Gross, associate professor of internal medicine at Yale School of Medicine and director of the Cancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center at Yale, the study sought to provide a comprehensive understanding of breast cancer expenditures that incorporate the cost of screening and associated work-up, as well as treatment. They assessed overall national costs, as well as variation in costs across geographic regions. (more…)

Cognitive Behavioural Therapy Proves Effective at Reducing Depression in People Who Have not Responded to Antidepressants

By Guest PostDecember 12, 2012Healthantidepressant medication, antidepressants, australia, bristol, cbt, chris williams, cobait team, cognitive behavioural therapy, controlled trial, depression, emer oneill, exeter, first line treatment, glasgow, john campbell, mood disorders centre, nicola wiles, patients, psychological treatments, symptoms, talking therapy, treatment, uk, universities, willem kuyken, World Health Organisation

Antidepressants are the most widely used treatment for people with moderate to severe depression.

However, up to two thirds of people with depression don’t respond fully to this type of treatment. New findings have shown cognitive behavioural therapy (CBT), provided in addition to usual care, can reduce symptoms of depression and help improve patients’ quality of life.

This is the first large-scale trial to test the effectiveness of CBT – a type of talking psychotherapy- given in addition to usual care that includes antidepressants. The National Institute for Health Research Health Technology Assessment (NIHR HTA)-funded CoBalT study aimed to determine the best ‘next step’ treatment for people whose depression had not responded to medication alone. (more…)

Promising Nanotechnology

By Guest PostDecember 5, 2012Sciencea k rajasekaran, acute lymphoblastic leukemia, all, alternative, biomedical engineering, cancer cell, chemotherapy, childhood leukemia, delaware scientist, dex, drug treatment, encapsulated dexamethasone, healthy cell, mouse model, Nanotechnology, normal cell, pediatric leukemia, side effect, treatment, university of delaware, vinu krishnan, xian xu, xiaowei yang, xinqiao jia

Nanotechnology for drug delivery shows promise in treatment of pediatric leukemia

Nanotechnology developed by Delaware scientists could potentially deliver chemotherapy to children in a way that attacks cancer cells without harming healthy cells, greatly reducing side effects.

The work, conducted by researchers in the University of Delaware’s Department of Materials Science and Engineering and Nemours Center for Childhood Cancer Research, was published this month in the journal Molecular Pharmaceutics. (more…)

Old Habits Die Hard: Helping Cancer Patients Stop Smoking

By Guest PostNovember 26, 2012Healthann arbor, cancer diagnosis, death, familiar scene, hospital gowned patients, iv poles, lung cancer, medical campuses, nicotine addiction, program, quit smoking, smoking cigarettes, sonia duffy, treatment, university of michigan, va center

ANN ARBOR — It’s a sad but familiar scene near the grounds of many medical campuses: hospital-gowned patients, some toting rolling IV poles, huddled in clumps under bus shelters or warming areas, smoking cigarettes.

Smoking causes 30 percent of all cancer deaths and 87 percent of all lung cancer deaths. Yet, roughly 50 percent to 83 percent of cancer patients keep smoking after a cancer diagnosis, through treatment and beyond, says Sonia Duffy, University of Michigan School of Nursing researcher. For patients who quit on their own, relapse rates (as in the general population) are as high as 85 percent. (more…)

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